SHMT1 (AK091498) Human Untagged Clone

CAT#: SC311605

(untagged)-Human cDNA FLJ34179 fis, clone FCBBF3016622, weakly similar to SERINE HYDROXYMETHYLTRANSFERASE, CYTOSOLIC (EC 2.1.2.1)

USD 907


Availability*
3 Weeks

Size
    • 10 ug

Product images

Specifications

Product Data
Product Name SHMT1 (AK091498) Human Untagged Clone
Symbol SHMT1
Vector pCMV6-XL
Sequence Data
Fully Sequenced ORF
>NCBI ORF sequence for AK091498, the custom clone sequence may differ by one or more nucleotides

Tag Tag Free
ACCN AK091498
ORF Size 3088 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reference Data
RefSeq Size 3088
RefSeq ORF 3088
Locus ID 6470
Cytogenetics 17p11.2
Protein Pathways Glycine, serine and threonine metabolism, Cyanoamino acid metabolism, One carbon pool by folate, Methane metabolism, Metabolic pathways
Gene Summary This gene encodes the cytosolic form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one-carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. A pseudogene of this gene is located on the short arm of chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013].
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.