SIRT4 (NM_012240) Human Untagged Clone

CAT#: SC310543

SIRT4 (untagged)-Human sirtuin 4 (SIRT4)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SIRT4
• Synonyms: SIR2L4
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_012240 edited
  GTCCGTAGAGCTGTGAGAGAATGAAGATGAGCTTTGCGTTGACTTTCAGGTCAGCAAAAG
  GCCGTTGGATCGCAAACCCCAGCCAGCCGTGCTCGAAAGCCTCCATTGGGTTATTTGTGC
  CAGCAAGTCCTCCTCTGGACCCTGAGAAGGTCAAAGAGTTACAGCGCTTCATCACCCTTT
  CCAAGAGACTCCTTGTGATGACTGGGGCAGGAATCTCCACCGAATCGGGGATACCAGACT
  ACAGGTCAGAAAAAGTGGGGCTTTATGCCCGCACTGACCGCAGGCCCATCCAGCATGGTG
  ATTTTGTCCGGAGTGCCCCAATCCGCCAGCGGTACTGGGCGAGAAACTTCGTAGGCTGGC
  CTCAATTCTCCTCCCACCAGCCTAACCCTGCACACTGGGCTTTGAGCACCTGGGAGAAAC
  TCGGAAAGCTGTACTGGTTGGTGACCCAAAATGTGGATGCTTTGCACACCAAGGCGGGGA
  GTCGGCGCCTGACAGAGCTCCACGGATGCATGGACAGGGTCCTGTGCTTGGATTGTGGGG
  AACAGACTCCCCGGGGGGTGCTGCAAGAGCGTTTCCAAGTCCTGAACCCCACCTGGAGTG
  CTGAGGCCCATGGCCTGGCTCCTGATGGTGACGTCTTTCTCTCAGAGGAGCAAGTCCGGA
  GCTTTCAGGTCCCAACCTGCGTTCAATGTGGAGGCCATCTGAAACCAGATGTCGTTTTCT
  TCGGGGACACAGTGAACCCTGACAAGGTTGATTTTGTGCACAAGCGTGTAAAAGAAGCCG
  ACTCCCTCTTGGTGGTGGGATCATCCTTGCAGGTATACTCTGGTTACAGGTTTATCCTCA
  CTGCCTGGGAGAAGAAGCTCCCGATTGCAATACTGAACATTGGGCCCACACGGTCGGATG
  ACTTGGCGTGTCTGAAACTGAATTCTCGTTGTGGAGAGTTGCTGCCTTTGATAGACCCAT
  GCTGACCACAGCCTGATATTCCAGAACCTGGAACAGGGACTTTCACTTGAATCTTGCTGC
  TAAATGTAAATGCCTTCTCAAATGACAGATTCCAGTTCCCATTCAACAGAGTAGGGTGC
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_012240 unedited
  NNNTTTTGGGGGGGTTCAAATTTGTATACGACTCACTATAGGGCGGCCGCCAGTGTGATG
  GAATCTGCAGAATTCGCCCTTGTCCGTAGAGCTGTGAGAGAATGAAGATGAGCTTTGCGT
  TGACTTTCAGGTCAGCAAAAGGCCGTTGGATCGCAAACCCCAGCCAGCCGTGCTCGAAAG
  CCTCCATTGGGTTATTTGTGCCAGCAAGTCCTCCTCTGGACCCTGAGAAGGTCAAAGAGT
  TACAGCGCTTCATCACCCTTTCCAAGAGACTCCTTGTGATGACTGGGGCAGGAATCTCCA
  CCGAATCGGGGATACCAGACTACAGGTCAGAAAAAGTGGGGCTTTATGCCCGCACTGACC
  GCAGGCCCATCCAGCATGGTGATTTTGTCCGGAGTGCCCCAATCCGCCAGCGGTACTGGG
  CGAGAAACTTCGTAGGCTGGCCTCAATTCTCCTCCCACCAGCCTAACCCTGCACACTGGG
  CTTTGAGCACCTGGGAGAAACTCGGAAAGCTGTACTGGTTGGTGACCCAAAATGTGGATG
  CTTTGCACACCAAGGCGGGGAGTCGGCGCCTGACAGAGCTCCACGGATGCATGGACAGGG
  TCCTGTGCTTGGATTGTGGGGAACAGACTCCCCGGGGGGTGCTGCAAGAGCGTTTCCAAG
  TCCTGAACCCCACCTGGAGTGCTGAGGCCCATGGCCTGGCTCCTGATGGTGACGTCTTTC
  TCTCAGAGGAGCAAGTCCGGAGCTTTCAGGTCCCAACCTGCGTTCAATGTGGAGGCCATC
  TGAAACCAGATGTCGTTTTCTTCGGGGACACAGTGAACCCTGACAGGTTGATTTTGTGCA
  CCAGCGTGTAAAAGAAGCCGNACTCCTCTTGGTGGN
  
• Restriction Sites: Please inquire
• ACCN: NM_012240
• Insert Size: 1100 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_012240.1, NP_036372.1
• RefSeq Size: 1174 bp
• RefSeq ORF: 945 bp
• Locus ID: 23409
• UniProt ID: Q9Y6E7
• Cytogenetics: 12q24.23-q24.31
• Domains: SIR2
• Protein Families: Druggable Genome, Transcription Factors
• Gene Summary: This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. [provided by RefSeq, Jul 2008]