NRP2 (NM_201266) Human Untagged Clone

CAT#: SC308003

NRP2 (untagged)-Human neuropilin 2 (NRP2), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NRP2
• Synonyms: NP2; NPN2; PRO2714; VEGF165R2
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >SC308003 representing NM_201266.
  Blue=Insert sequence Red=Cloning site Green=Tag(s)
  
  GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG
  GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC
  ATGGATATGTTTCCTCTCACCTGGGTTTTCTTAGCCCTCTACTTTTCAAGACACCAAGTGAGAGGCCAA
  CCAGACCCACCGTGCGGAGGTCGTTTGAATTCCAAAGATGCTGGCTATATCACCTCTCCCGGTTACCCC
  CAGGACTACCCCTCCCACCAGAACTGCGAGTGGATTGTTTACGCCCCCGAACCCAACCAGAAGATTGTC
  CTCAACTTCAACCCTCACTTTGAAATCGAGAAGCACGACTGCAAGTATGACTTTATCGAGATTCGGGAT
  GGGGACAGTGAATCCGCAGACCTCCTGGGCAAACACTGTGGGAACATCGCCCCGCCCACCATCATCTCC
  TCGGGCTCCATGCTCTACATCAAGTTCACCTCCGACTACGCCCGGCAGGGGGCAGGCTTCTCTCTGCGC
  TACGAGATCTTCAAGACAGGCTCTGAAGATTGCTCAAAAAACTTCACAAGCCCCAACGGGACCATCGAA
  TCTCCTGGGTTTCCTGAGAAGTATCCACACAACTTGGACTGCACCTTTACCATCCTGGCCAAACCCAAG
  ATGGAGATCATCCTGCAGTTCCTGATCTTTGACCTGGAGCATGACCCTTTGCAGGTGGGAGAGGGGGAC
  TGCAAGTACGATTGGCTGGACATCTGGGATGGCATTCCACATGTTGGCCCCCTGATTGGCAAGTACTGT
  GGGACCAAAACACCCTCTGAACTTCGTTCATCGACGGGGATCCTCTCCCTGACCTTTCACACGGACATG
  GCGGTGGCCAAGGATGGCTTCTCTGCGCGTTACTACCTGGTCCACCAAGAGCCACTAGAGAACTTTCAG
  TGCAATGTTCCTCTGGGCATGGAGTCTGGCCGGATTGCTAATGAACAGATCAGTGCCTCATCTACCTAC
  TCTGATGGGAGGTGGACCCCTCAACAAAGCCGGCTCCATGGTGATGACAATGGCTGGACCCCCAACTTG
  GATTCCAACAAGGAGTATCTCCAGGTGGACCTGCGCTTTTTAACCATGCTCACGGCCATCGCAACACAG
  GGAGCGATTTCCAGGGAAACACAGAATGGCTACTATGTCAAATCCTACAAGCTGGAAGTCAGCACTAAT
  GGAGAGGACTGGATGGTGTACCGGCATGGCAAAAACCACAAGGTATTTCAAGCCAACAACGATGCAACT
  GAGGTGGTTCTGAACAAGCTCCACGCTCCACTGCTGACAAGGTTTGTTAGAATCCGCCCTCAGACCTGG
  CACTCAGGTATCGCCCTCCGGCTGGAGCTCTTCGGCTGCCGGGTCACAGATGCTCCCTGCTCCAACATG
  CTGGGGATGCTCTCAGGCCTCATTGCAGACTCCCAGATCTCCGCCTCTTCCACCCAGGAATACCTCTGG
  AGCCCCAGTGCAGCCCGCCTGGTCAGCAGCCGCTCGGGCTGGTTCCCTCGAATCCCTCAGGCCCAGCCC
  GGTGAGGAGTGGCTTCAGGTAGATCTGGGAACACCCAAGACAGTGAAAGGTGTCATCATCCAGGGAGCC
  CGCGGAGGAGACAGTATCACTGCTGTGGAAGCCAGAGCATTTGTGCGCAAGTTCAAAGTCTCCTACAGC
  CTAAACGGCAAGGACTGGGAATACATTCAGGACCCCAGGACCCAGCAGCCAAAGCTGTTCGAAGGGAAC
  ATGCACTATGACACCCCTGACATCCGAAGGTTTGACCCCATTCCGGCACAGTATGTGCGGGTATACCCG
  GAGAGGTGGTCGCCGGCGGGGATTGGGATGCGGCTGGAGGTGCTGGGCTGTGACTGGACAGACTCCAAG
  CCCACGGTAGAGACGCTGGGACCCACTGTGAAGAGCGAAGAGACAACCACCCCCTACCCCACCGAAGAG
  GAGGCCACAGAGTGTGGGGAGAACTGCAGCTTTGAGGATGACAAAGATTTGCAGCTCCCTTCGGGATTC
  AATTGCAACTTCGATTTCCTCGAGGAGCCCTGTGGTTGGATGTATGACCATGCCAAGTGGCTCCGGACC
  ACCTGGGCCAGCAGCTCCAGCCCAAACGACCGGACGTTTCCAGATGACAGGAATTTCTTGCGGCTGCAG
  AGTGACAGCCAGAGAGAGGGCCAGTATGCCCGGCTCATCAGCCCCCCTGTCCACCTGCCCCGAAGCCCG
  GTGTGCATGGAGTTCCAGTACCAGGCCACGGGCGGCCGCGGGGTGGCGCTGCAGGTGGTGCGGGAAGCC
  AGCCAGGAGAGCAAGTTGCTGTGGGTCATCCGTGAGGACCAGGGCGGCGAGTGGAAGCACGGGCGGATC
  ATCCTGCCCAGCTACGACATGGAGTACCAGATTGTGTTCGAGGGAGTGATAGGGAAAGGACGTTCCGGA
  GAGATTGCCATTGATGACATTCGGATAAGCACTGATGTCCCACTGGAGAACTGCATGGAACCCATCTCG
  GCTTTTGCAGGTGAGAATTTTAAAGTGGACATCCCAGAAATACATGAGAGAGAAGGATATGAAGATGAA
  ATTGATGATGAATACGAGGTGGACTGGAGCAATTCTTCTTCTGCAACCTCAGGGTCTGGCGCCCCCTCG
  ACCGACAAAGAAAAGAGCTGGCTGTACACCCTGGATCCCATCCTCATCACCATCATCGCCATGAGCTCA
  CTGGGCGTCCTCCTGGGGGCCACCTGTGCAGGCCTCCTGCTCTACTGCACCTGTTCCTACTCGGGCCTG
  AGCTCCCGAAGCTGCACCACACTGGAGAACTACAACTTCGAGCTCTACGATGGCCTTAAGCACAAGGTC
  AAGATGAACCACCAAAAGTGCTGCTCCGAGGCATGA
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT
  TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_201266
• Insert Size: 2796 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_201266.1
• RefSeq Size: 6671 bp
• RefSeq ORF: 2796 bp
• Locus ID: 8828
• UniProt ID: O60462
• Cytogenetics: 2q33.3
• Protein Families: Druggable Genome, Transmembrane
• MW: 104.8 kDa
• Gene Summary: This gene encodes a member of the neuropilin family of receptor proteins. The encoded transmembrane protein binds to SEMA3C protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C} and SEMA3F protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F}, and interacts with vascular endothelial growth factor (VEGF). This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1), also known as NRP2a(22), represents the longest transcript, and encodes the longest isoform (1).