BMP9 (GDF2) (NM_016204) Human Untagged Clone

CAT#: SC304392

GDF2 (untagged)-Human growth differentiation factor 2 (GDF2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: BMP9
• Synonyms: BMP-9; BMP9; HHT5
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_016204 edited
  CTCCTTCCCAGCTCCTCCCCGTGCCCGCTAACACAGCACGGCCGCCTGCAGTCTCCTCTC
  TGGGTGATTGCGCGGGCCTAAGATGTGTCCTGGGGCACTGTGGGTGGCCCTGCCCCTGCT
  GTCCCTGCTGGCTGGCTCCCTACAGGGGAAGCCACTGCAGAGCTGGGGACGAGGGTCTGC
  TGGGGGAAACGCCCACAGCCCACTGGGGGTGCCTGGAGGTGGGCTGCCTGAGCACACCTT
  CAACCTGAAGATGTTTCTGGAGAACGTGAAGGTGGATTTCCTGCGCAGCCTTAACCTGAG
  TGGGGTCCCTTCGCAGGACAAAACCAGGGTGGAGCCGCCGCAGTACATGATTGACCTGTA
  CAACAGGTACACGTCCGATAAGTCGACTACGCCAGCGTCCAACATTGTGCGGAGCTTCAG
  CATGGAAGATGCCATCTCCATAACTGCCACAGAGGACTTCCCCTTCCAGAAGCACATCTT
  GCTCTTCAACATCTCCATTCCTAGGCATGAGCAGATCACCAGAGCTGAGCTCCGACTCTA
  TGTCTCCTGTCAAAATCACGTGGACCCCTCTCATGACCTGAAAGGAAGCGTGGTCATTTA
  TGATGTTCTGGATGGAACAGATGCCTGGGATAGTGCTACAGAGACCAAGACCTTCCTGGT
  GTCCCAGGACATTCAGGATGAGGGCTGGGAGACCTTGGAAGTGTCCAGCGCCGTGAAGCG
  CTGGGTCCGGTCCGACTCCACCAAGAGCAAAAATAAGCTGGAAGTGACTGTGGAGAGCCA
  CAGGAAGGGCTGCGACACGCTGGACATCAGTGTCCCCCCAGGTTCCAGAAACCTGCCCTT
  CTTTGTTGTCTTCTCCAATGACCACAGCAGTGGGACCAAGGAGACCAGGCTGGAGCTGAG
  GGAGATGATCAGCCATGAACAAGAGAGCGTGCTCAAGAAGCTGTCCAAGGACGGCTCCAC
  AGAGGCAGGTGAGAGCAGTCACGAGGAGGACACGGATGGCCACGTGGCTGCGGGGTCGAC
  TTTAGCCAGGCGGAAAAGGAGCGCCGGGGCTGGCAGCCACTGTCAAAAGACCTCCCTGCG
  GGTAAACTTCGAGGACATCGGCTGGGACAGCTGGATCATTGCACCCAAGGAGTATGAAGC
  CTACGAGTGTAAGGGCGGCTGCTTCTTCCCCTTGGCTGACGATGTGACGCCGACGAAACA
  CGCTATCGTGCAGACCCTGGTGCATCTCAAGTTCCCCACAAAGGTGGGCAAGGCCTGCTG
  TGTGCCCACCAAACTGAGCCCCATCTCCGTCCTCTACAAGGATGACATGGGGGTGCCCAC
  CCTCAAGTACCATTACGAGGGCATGAGCGTGGCAGAGTGTGGGTGCAGGTAGTATCTGCC
  TGCGGGGCTGGGGAGGCAGGCCAAAGGGGCTCCACATGAGAGGTCCTGCATGCCCCTGGG
  CACAACAAGGACTGATTCAATCTGCATGCCAGCCTGGAGGAGGAAAGGGAG
  
• Restriction Sites: Please inquire
• ACCN: NM_016204
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This clone was fully sequenced and found to be a perfect match to NM_016204.1.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_016204.1, NP_057288.1
• RefSeq Size: 1942 bp
• RefSeq ORF: 1290 bp
• Locus ID: 2658
• UniProt ID: Q9UK05
• Cytogenetics: 10q11.22
• Protein Families: Druggable Genome, Secreted Protein
• Gene Summary: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates cartilage and bone development, angiogenesis and differentiation of cholinergic central nervous system neurons. Mutations in this gene are associated with hereditary hemorrhagic telangiectasia. [provided by RefSeq, Jul 2016]