CD36 (NM_001001547) Human Untagged Clone

CAT#: SC300209

CD36 (untagged)-Human CD36 molecule (thrombospondin receptor) (CD36), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CD36
• Synonyms: BDPLT10; CHDS7; FAT; GP3B; GP4; GPIV; PASIV; SCARB3
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_001001547 edited
  ACATCTCCGAAAGCAAGCTCTTCTAGAAGTTGATAGCTTTCCAATGATTAGACGAATTGA
  TTCTTTCTGTGACTCATCAGTTCATTTCCTGTAAAATTCATGTCTTGCTGTTGATTTGTG
  AATAAGAACCAGAGCTTGTAGAAACCACTTTAATCATATCCAGGAGTTTGCAAGAAACAG
  GTGCTTAACACTAATTCACCTCCTGAACAAGAAAAATGGGCTGTGACCGGAACTGTGGGC
  TCATCGCTGGGGCTGTCATTGGTGCTGTCCTGGCTGTGTTTGGAGGTATTCTAATGCCAG
  TTGGAGACCTGCTTATCCAGAAGACAATTAAAAAGCAAGTTGTCCTCGAAGAAGGTACAA
  TTGCTTTTAAAAATTGGGTTAAAACAGGCACAGAAGTTTACAGACAGTTTTGGATCTTTG
  ATGTGCAAAATCCACAGGAAGTGATGATGAACAGCAGCAACATTCAAGTTAAGCAAAGAG
  GTTCTTATACGTACAGAGTTCGTTTTCTAGCCAAGGAAAATGTAACCCAGGACGCTGAGG
  ACAACACAGTCTCTTTCCTGCAGCCCAATGGTGCCATCTTCGAACCTTCACTATCAGTTG
  GAACAGAGGCTGACAACTTCACAGTTCTCAATCTGGCTGTGGCAGCTGCATCCCATATCT
  ATCAAAATCAATTTGTTCAAATGATCCTCAATTCACTTATTAACAAGTCAAAATCTTCTA
  TGTTCCAAGTCAGAACTTTGAGAGAACTGTTATGGGGCTATAGGGATCCATTTTTGAGTT
  TGGTTCCGTACCCTGTTACTACCACAGTTGGTCTGTTTTATCCTTACAACAATACTGCAG
  ATGGAGTTTATAAAGTTTTCAATGGAAAAGATAACATAAGTAAAGTTGCCATAATCGACA
  CATATAAAGGTAAAAGGAATCTGTCCTATTGGGAAAGTCACTGCGACATGATTAATGGTA
  CAGATGCAGCCTCATTTCCACCTTTTGTTGAGAAAAGCCAGGTATTGCAGTTCTTTTCTT
  CTGATATTTGCAGGTCAATCTATGCTGTATTTGAATCCGACGTTAATCTGAAAGGAATCC
  CTGTGTATAGATTTGTTCTTCCATCCAAGGCCTTTGCCTCTCCAGTTGAAAACCCAGACA
  ACTATTGTTTCTGCACAGAAAAAATTATCTCAAAAAATTGTACATCATATGGTGTGCTAG
  ACATCAGCAAATGCAAAGAAGGGAGACCTGTGTACATTTCACTTCCTCATTTTCTGTATG
  CAAGTCCTGATGTTTCAGAACCTATTGATGGATTAAACCCAAATGAAGAAGAACATAGGA
  CATACTTGGATATTGAACCTATAACTGGATTCACTTTACAATTTGCAAAACGGCTGCAGG
  TCAACCTATTGGTCAAGCCATCAGAAAAAATTCAAGTATTAAAGAATCTGAAGAGGAACT
  ATATTGTGCCTATTCTTTGGCTTAATGAGACTGGGACCATTGGTGATGAGAAGGCAAACA
  TGTTCAGAAGTCAAGTAACTGGAAAAATAAACCTCCTTGGCCTGATAGAAATGATCTTAC
  TCAGTGTTGGTGTGGTGATGTTTGTTGCTTTTATGATTTCATATTGTGCATGCAGATCGA
  AAACAATAAAATAACCTGGCTCAAGCACAAACCAATTTGTGTTGTTCTGATTCAATAATT
  GGTTTCTGGGTGGCCAATTCAGAAGAAGAGTGTACATGCTCAACAAATCCTAGGCCCTGC
  ATTCCTGTCATCCTCATCCGGGGGAAACACCATCATCCCAGTAGCTGCCCTATTCAACTG
  CAACAGTCTCCAGGACCATCAGTATACTGCATTTCATGTGCACCAAATATTTTGAAAGAC
  ATTTATAAATAATTGGCTTATGACTCATATTTCTCTATGAATACCTTCATACAGCAGGTA
  TAACTCTTTTCTTTATGGGCTTAAATATTTTGTCACTGATCCTGCAAATGGACATCATTT
  TAGCACACTAGCGGTTTATATTTTAAGGACCTTCATTCTCTGTTCTGCACCTCTTCTGGA
  AATTGAGTAAATTTTGCTTTTTTTTTTTACTCAGTTGCAACTTACGCTTGGCATCTTCAG
  AATGCTTTTCTAGCATTAAGAGATGTAAATGATAAAGGAATTATTGTATGAAATATTACA
  AAGCGTAGACTATGCATTGTTATTCATTATAATATTTTTTGCTATCATAATCGCCTCATA
  AAGACAGGTTTCAACCATTAAAATATGTTCTTCCTTAAAAAAAAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001001547 unedited
  NNGGTCAACATTTGTATACGACTCCTATAGGCGGCNCGCGAATTCGCACCAGACATCTCC
  GAAAGCAGCTCTTCTAGAAGTTGATAGCTTTCCAATGATTAGACGAATTGATTCTTTCTG
  TGACTCATCAGTTCATTTCCTGTAAAATTCATGTCTTGCTGTTGATTTGTGAATAAGAAC
  CAGAGCTTGTAGAAACCACTTTAATCATATCCAGGAGTTTGCAAGAAACAGGTGCTTAAC
  ACTAATTCACCTCCTGAACAAGAAAAATGGGCTGTGACCGGAACTGTGGGCTCATCGCTG
  GGGCTGTCATTGGTGCTGTCCTGGCTGTGTTTGGAGGTATTCTAATGCCAGTTGGAGACC
  TGCTTATCCAGAAGACAATTAAAAAGCAAGTTGTCCTCGAAGAAGGTACAATTGCTTTTA
  AAAATTGGGTTAAAACAGGCACAGAAGTTTACAGACAGTTTTGGATCTTTGATGTGCAAA
  ATCCACAGGAAGTGATGATGAACAGCAGCAACATTCAAGTTAAGCAAAGAGGTTCTTATA
  CGTACAGAGTTCGTTTTCTAGCCAAGGAAAATGTAACCCAGGACGCTGAGGACAACACAG
  TCTCTTTCCTGCAGCCCAATGGTGCCATCTTCGAACCTTCACTATCAGTTGGAACAGAGG
  CTGACAACTTCACAGTTCTCAATCTGGCTGTGGCAGCTGCATCCCATATCTATCANAATC
  AATTTGTTCAAATGATCCTCAATTCACTTATTAACAAGTCANAATCTTCTATTGNTNCCA
  GTCAGAACTTTGAGAGAACTGTTATGGGGCTATTAGGNATCCATTNTTGAAGNTTNGGNT
  NCCGTACCCTGNTACTACCACAGNTGGGTCTGTTTTATTCCTACAACATACTGCAGATGG
  AGTTTATAAAAGTTTCATGGGNAAGATAACATAAGTAAAGTTGCATTATCGACCATATAA
  NGGGTAAGGAT
  
  3' Read Nucleotide Sequence

  >OriGene 3' genomic read for NM_001001547 unedited
  TCGCGATGCACCTTCAGGGCAGGAAGCACTGGGGAGGGGTCACAGGGCATGCCACCCGGG
  ATCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTT
  TTTTTTTTTTAAGGAAGAACATATTTTAATGGTTGAAACCTGTCTTTATGAGGCGATTAT
  GATAGCAAAAAATATTATAATGAATAACAATGCATAGTCTACGCTTTGTAATATTTCATA
  CAATAATTCCTTTATCATTTACATCTCTTAATGCTAGAAAAGCATTCTGAAGATGCCAAG
  CGTAAGTTGCAACTGAGTAAAAAAAAAAAGCAAAATTTACTCAATTTCCAGAAGAGGTGC
  AGAACAGAGAATGAAGGTCCTTAAAATATAAACCGCTAGTGTGCTAAAATGATGTCCATT
  TGCAGGATCAGTGACAAAATATTTAAGCCCATAAAGAAAAGAGTTATACCTGCTGTATGA
  AGGTATTCATAGAGAAATATGAGTCATAAGCCAATTATTTATAAATGTCTTTCAAAATAT
  TTGGTGCACATGAAATGCAGTATACTGATGGTCCTGGAGACTGTTGCAGTTGAATAGGGC
  AGCTACTGGGATGATGGTGTTTCCCCCGGATGAGGATGACAGGAATGCAGGGCCTAGGAT
  TTGTTGAGCATGTACACTCTTCTTCTGAATTGGCCACCCCAGAAACCAATTATTGAATCA
  GAACAACACAATTGGTTTTGTGCTTGAGCCAGGTTTATTTTATTGTTTTCGATCTGCATG
  CACAATATGAAATCATAAAGCAACAAACATCACCCACACCAACACTGAGTAGATCATTTC
  TATCAGCCAGAGTTTATTTTTCAGTTACTTGACTTCTGAACATGTTTGCCTTCTCATCAC
  C
  
• Restriction Sites: NotI-NotI
• ACCN: NM_001001547
• Insert Size: 2300 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: There is 1 nucleotide difference between the OriGene clone and the NCBI reference ORF. These result in the substitution of 1 aa.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001001547.1, NP_001001547.1
• RefSeq Size: 2050 bp
• RefSeq ORF: 1419 bp
• Locus ID: 948
• UniProt ID: P16671
• Cytogenetics: 7q21.11
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Adipocytokine signaling pathway, ECM-receptor interaction, Hematopoietic cell lineage, PPAR signaling pathway
• Gene Summary: The protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2014]
  Transcript Variant: This variant (2) has an alternate 5' UTR exon, compared to variant 3. Variants 1 through 5 all encode the same isoform 1.