FYN (NM_153048) Human Untagged Clone

SKU SC128257

FYN (untagged)-Human FYN oncogene related to SRC, FGR, YES (FYN), transcript variant 3

Product Data

• Type: Human Untagged Clone
• Target Symbol: FYN
• Synonyms: p59-FYN; SLK; SYN
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_153048 edited; CAGCGCAGGTCTGAGGAGCTGAGAAGGGAGGCTTACGTGAAGGGAATTTAGATAATGGGC; TGTGTGCAATGTAAGGATAAAGAAGCAACAAAACTGACGGAGGAGAGGGACGGCAGCCTG; AACCAGAGCTCTGGGTACCGCTATGGCACAGACCCCACCCCTCAGCACTACCCCAGCTTC; GGTGTGACCTCCATCCCCAACTACAACAACTTCCACGCAGCCGGGGGCCAAGGACTCACC; GTCTTTGGAGGTGTGAACTCTTCGTCTCATACGGGGACCTTGCGTACGAGAGGAGGAACA; GGAGTGACACTCTTTGTGGCCCTTTATGACTATGAAGCACGGACAGAAGATGACCTGAGT; TTTCACAAAGGAGAAAAATTTCAAATATTGAACAGCTCGGAAGGAGATTGGTGGGAAGCC; CGCTCCTTGACAACTGGAGAGACAGGTTACATTCCCAGCAATTATGTGGCTCCAGTTGAC; TCTATCCAGGCAGAAGAGTGGTACTTTGGAAAACTTGGCCGAAAAGATGCTGAGCGACAG; CTATTGTCCTTTGGAAACCCAAGAGGTACCTTTCTTATCCGCGAGAGTGAAACCACCAAA; GGTGCCTATTCACTTTCTATCCGTGATTGGGATGATATGAAAGGAGACCATGTCAAACAT; TATAAAATTCGCAAACTTGACAATGGTGGATACTACATTACCACCCGGGCCCAGTTTGAA; ACACTTCAGCAGCTTGTACAACATTACTCAGGTACCTGGAATGGAAACACAAAAGTAGCC; ATAAAGACTCTTAAACCAGGCACAATGTCCCCCGAATCATTCCTTGAGGAAGCGCAGATC; ATGAAGAAGCTGAAGCACGACAAGCTGGTCCAGCTCTATGCAGTGGTGTCTGAGGAGCCC; ATCTACATCGTCACCGAGTATATGAACAAAGGAAGTTTACTGGATTTCTTAAAAGATGGA; GAAGGAAGAGCTCTGAAATTACCAAATCTTGTGGACATGGCAGCACAGGTGGCTGCAGGA; ATGGCTTACATCGAGCGCATGAATTATATCCATAGAGATCTGCGATCAGCAAACATTCTA; GTGGGGAATGGACTCATATGCAAGATTGCTGACTTCGGATTGGCCCGATTGATAGAAGAC; AATGAGTACACAGCAAGACAAGGTGCAAAGTTCCCCATCAAGTGGACGGCCCCCGAGGCA; GCCCTGTACGGGAGGTTCACAATCAAGTCTGACGTGTGGTCTTTTGGAATCTTACTCACA; GAGCTGGTCACCAAAGGAAGAGTGCCATACCCAGGCATGAACAACCGGGAGGTGCTGGAG; CAGGTGGAGCGAGGCTACAGGATGCCCTGCCCGCAGGACTGCCCCATCTCTCTGCATGAG; CTCATGATCCACTGCTGGAAAAAGGACCCTGAAGAACGCCCCACTTTTGAGTACTTGCAG; AGCTTCCTGGAAGACTACTTTACCGCGACAGAGCCCCAGTACCAACCTGGTGAAAACCTG; TAAGGCCCGGGTCTGCGGAGAGAGGCCTTGTCCCAGAGGCTGCCCCACCCCTCCCCATTA; GCTTTCAATTCCGTAGCCAGCTGCTCCCCAGCAGCGGAACCGCCCAGGATCAGATTGCAT; GTGACTCTGAAGCTGACGAACTTCCATGGCCCTCATTAATGACACTTGTCCCCAAATCCG; AACCTCCTCTGTGAAGCATTCGAGACAGAACCTTGTTATTTCTCAGACTTTGGAAAATGC; ATTGTATCGATGTTATGTAAAAGGCCAAACCTCTGTTCAGTGTAAATAGTTACTCCAGTG; CCAACAATCCTAGTGCTTTCCTTTTTTAAAAATGCAAATCCTATGTGATTTTAACTCTGT; CTTCACCTGATTCAACTAAAAAAAAAAAAGTATTATTTTCCAAAAGTGGCCTCTTTGTCT; AAAACAATAAAATTTTTTTTCATGTTTTAACAAAAACCAAAAAAAAAAAAAAAAAAAAAA; AAAAAAAAAAAAAAAAAAAA;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_153048 unedited; GGTTCACATTTTGTATACGACTCATATAGGCGGCCGCGNATTCCCGGGNATCAGCGCAGT; CTGAGGAGCTGAGAAGGAGGCTTACGTGAAGGGAATTTAGATAATGGGCTGTGTGCAATG; TAAGGATAAAGAAGCAACAAAACTGACGGAGGAGAGGGACGGCAGCCTGAACCAGAGCTC; TGGGTACCGCTATGGCACAGACCCCACCCCTCAGCACTACCCCAGCTTCGGTGTGACCTC; CATCCCCAACTACAACAACTTCCACGCAGCCGGGGGCCAAGGACTCACCGTCTTTGGAGG; TGTGAACTCTTCGTCTCATACGGGGACCTTGCGTACGAGAGGAGGAACAGGAGTGACACT; CTTTGTGGCCCTTTATGACTATGAAGCACGGACAGAAGATGACCTGAGTTTTCACAAAGG; AGAAAAATTTCAAATATTGAACAGCTCGGAAGGAGATTGGTGGGAAGCCCGCTCCTTGAC; AACTGGAGAGACAGGTTACATTCCCAGCAATTATGTGGCTCCAGTTGACTCTATCCAGGC; AGAAGAGTGGTACTTTGGAAAACTTGGCCGANAAGATGCTGAGCGACAGCTATTGTCCTT; TGGAAACCCAAGAGGTACCTTTCTTATCCGCGAGAGTGAAACCACCAAAGGTGCCTATTC; ACTTTCTATCCGTGATTGGGATGATATGAAAGGAGACCATGTCAAACATTATAAAATTCG; CAAACTTGACAATGGTGGATACTACATTACCACCCGGNCCCAGTTTTGAACACTTCAGCA; GCTTGTACAACATTACTCANGTACCTGNAATGGAAACACAAAGTAGCCATAAAGACTCTT; AAACANGCACAATGTTCCCCCGAATCATTCCTTTGAGAAGCGCANATCATGNAGAAGCTG; AAGCCACGACAGCTGG;
• Restriction Sites: Please inquire
• ACCN: NM_153048
• Insert Size: 2000 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_153048.1, NP_694593.1
• RefSeq Size: 2000 bp
• RefSeq ORF: 1449 bp
• Locus ID: 2534
• UniProt ID: P06241
• Cytogenetics: 6q21
• Domains: pkinase, SH2, SH3, S_TKc, TyrKc
• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Adherens junction, Axon guidance, Fc epsilon RI signaling pathway, Focal adhesion, Natural killer cell mediated cytotoxicity, Pathogenic Escherichia coli infection, Prion diseases, T cell receptor signaling pathway, Viral myocarditis
• Summary: This gene is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein. Alternatively spliced transcript variants encoding distinct isoforms exist. [provided by RefSeq, Jul 2008]; Transcript Variant: This variant (3) differs in the 5' UTR, and lacks an alternate in-frame exon in the central coding region, compared to variant 1, resulting in an isoform (c) that is shorter than isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.