EDA2R (NM_021783) Human Untagged Clone

CAT#: SC125820

EDA2R (untagged)-Human ectodysplasin A2 receptor (EDA2R), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: EDA2R
• Synonyms: EDA-A2R; EDAA2R; TNFRSF27; XEDAR
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_021783 edited
  CCGGAGTCCCATTTGGGAGCAAGAGCCATCTACTCGTCCGTTACCGGCCTTCCCACCATG
  GATTGCCAAGAAAATGAGTACTGGGACCAATGGGGACGGTGTGTCACCTGCCAACGGTGT
  GGTCCTGGACAGGAGCTATCCAAGGATTGTGGTTATGGAGAGGGTGGAGATGCCTACTGC
  ACAGCCTGCCCTCCTCGCAGGTACAAAAGCAGCTGGGGCCACCACAGATGTCAGAGTTGC
  ATCACCTGTGCTGTCATCAATCGTGTTCAGAAGGTCAACTGCACAGCTACCTCTAATGCT
  GTCTGTGGGGACTGTTTGCCCAGGTTCTACCGAAAGACACGCATTGGAGGCCTGCAGGAC
  CAAGAGTGCATCCCGTGCACGAAGCAGACCCCCACCTCTGAGGTTCAATGTGCCTTCCAG
  TTGAGCTTAGTGGAGGCAGATGCACCCACAGTGCCCCCTCAGGAGGCCACACTTGTTGCA
  CTGGTGAGCAGCCTGCTAGTGGTGTTTACCCTGGCCTTCCTGGGGCTCTTCTTCCTCTAC
  TGCAAGCAGTTCTTCAACAGACATTGCCAGCGTGGAGGTTTGCTGCAGTTTGAGGCTGAT
  AAAACAGCAAAGGAGGAATCTCTCTTCCCCGTGCCACCCAGCAAGGAGACCAGTGCTGAG
  TCCCAAGTGAGTGAGAACATCTTTCAGACCCAGCCACTTAACCCTATCCTCGAGGACGAC
  TGCAGCTCGACTAGTGGCTTCCCCACACAGGAGTCCTTTACCATGGCCTCCTGCACCTCA
  GAGAGCCACTCCCACTGGGTCCACAGCCCCATCGAATGCACAGAGCTGGACCTGCAAAAG
  TTTTCCAGCTCTGCCTCCTATACTGGAGCTGAGACCTTGGGGGGAAACACAGTCGAAAGC
  ACTGGAGACAGGCTGGAGCTCAATGTGCCCTTTGAAGTTCCCAGCCCTTAACTCTAATGA
  GGTCTCTTGGGCCCCTGGCAGCCTTGCCCAGTTGTTCTCTCTGGACTCTGTTCCTATACC
  ACAACAGCAGCAGGGGCCTGAAATGTGATGTCCACAAGAGCTAATACCCTACAGATGGGG
  CATATCCTATCCCATCCCACCAGAGGATTGATTCTCCATTTCACAAGGACTGATCTGGAG
  CATTTCTTGCTTCCCTTTTGTAGTCTGGGGAGCCAGATTCCACATTCATGGGACTACCAG
  ACATGTTCCTAGCTCAACTTGATTATAGAGAAGAGGAGAGAGGACAGTGAATGGGGTAGG
  GTTTTCATGTCTGCATTTTTGGTCAGGTAAGCCTCTCAAAATTGTGTTGGCACATCTACC
  TAGCACTTTAGGGACAAAATCAAACCCTTCTCCCCTTTTAGCTCCTCCACACTGTCTCCC
  TCCTCAACACACACACACACACATACACACACATATACATAGACACACAAACACACACAC
  ACACATTAATATCTATCTTGGGGGAGGCCTCGTGCCATAATTCCCAAGTTCATGTCTCAG
  ACTGCTGCATTGCAGCATGAGGCAGGGCAAACACTTTCCCTCTAGATCCCTGGGGCCTCA
  CCCTGTATTTGAGGTTCTCACCACCCTCAGCAGGGAGAAGGGCTGAAGTTCGCCATTTTG
  GAACCTTACAGAACATTTCTGAGCCAAAGTAATCTTCCTTCTGGGGCCTGAGTTCCCCAA
  ACTACCCCACAGCAGTCCCTCAAAGACAGCCCTCAATCCATGTAGGGACATCTGAGTATG
  CCTCTTTCTATTGAAATGTCAATTCAATCCCAGCTTTCTCACCACCGTTCCCCTTTGATT
  CTTTCTCAATTGTCTTTTTGCCTTTAGCTCCCACCTATACATCTCATGCTCAGAGAAAAA
  CAAGTTCCTTAGAGGTTGTATTCTTTATTCTCCAAGAATCTGTCTGAAACTTGTACAGCT
  AGTTCCTGTCCCACAACTATTAAGTGGTTTATTAAGTACATTAGGCAGAATGTGCACTTC
  ATCACCAGGTTCTAGCTCTGGCAAAGGAGTGCTGTCTACAGCAAGATTTTTGCTTTTAGA
  ATTTTATTAACTACATCTTTTGGGTTCATCCATCTACAAACACTGATTAAGGGCCCCTGG
  GGCAACCAATTGATCAGATTACTAAAAGGACTTGGGAAAAAGCAAAAAGGTCCCATTGTA
  CTGGACTGAGGATTAGAAGCAATTGAAATACAAGCCTGTACCAAGCAAGCAGCCTGGCCC
  CACACAGGTATTAGCAAATATGTGGTAACCAAGGTTTTAGGCCTTGGCCTTTAGGTTTCC
  TGTTTTTTTTTTGTTTTTGTTTTTGTTTTTGTTTTTCTGCAACAGGTTATTCTTATCTCA
  CTGGCTTTCACTGATCATGTTTAGACCTTCTGGTAGAAGAAATAATATCCAGACAGGGGA
  TGATTTGGCTTCAGCAGGCTGCAGGTGTTCAAAGGTTGCCATGTGGCTGGCAGTGGTTCA
  AGCCCACATTTGACACTGCTGCTCTAGAGGAAAGATAATGATGGTAACACAGTAATAATA
  ATAATAATAACAAAAATATGATAAAGTGAAAGAGTAAGACTTCTTCAGTGTGCTTGCTCA
  TGGCATGAATGCTATGTGGACAGCCCAAGCCATACCCAGAATCACCTTAATTCCAACTTT
  TTGAGGTTCAGCAATTGGAGGTGGCAATTGGCTTTGCATTTTAAAGTATTTCGGGTAAAG
  GTGAAGTGAAGGATTTTCGTCTTTATAATTTCTGTTTGGCCATGGCAAATACCATAGTTG
  AGTATTTGCTTCAGGAGAGTTCTTTTTACAGTTTTACTTTTCAATGCTGAGGCATATTTC
  TTTGAGCACTGTGCTTTTATGTGTCTTTCTACAAAGGGGTTATTGGTCAGTGGAAGAACA
  AAGTACACTTGATAAAAACATTTTCAACATACATTGAGCCTAAACAGCAGTTAAGTTGTC
  TCTAAATGAACTAGCAAAAAAAAAAAATGTAGTTTTTGTTTGTAAGGAAGGGGAGGTATT
  TCCTGAGAATGAATTTTTTTTTTTTTGGATTACTGTTTTTCTCTCCATATACCTTGACTT
  GGATTTTGACAGGAGGGAGCCTGGGAAAATAATTTTTTCCTCCAAGATTCTCAGATCCAG
  GTTAGGAAAGGATTCAGCACTACAGCATACCCCTCTACAACATACAGCCCTGTCACATTG
  AGATCATAATCCCTCCTGTCCCACTCCTCTCTACCAACCCCACCCTACTAGCTAGGTCTT
  CAGTGTTTTACATTGAATATTGGTACATTTTAATTATTTTTTCTCATAAATGGGTTATTT
  ATAGAAATTTTGTTAACTCTTGAGCCATATGCATGTGTAGATACTGGCAGGGCTATGTTT
  GTTTATGATGCTCTGCAAACATTTCATATTGGCCAATAAACAGAAATATATCCAAAAAAA
  AAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_021783 unedited
  GGTCATTATTTGTATACGACTCACTATAGGCGGCCGCGTAATTCGCACGAGGCCGGAGTC
  CCATTTGGGAGCAAGAGCCATCTACTCGTCCGTTACCGGCCTTCCCACCATGGATTGCCA
  AGAAAATGAGTACTGGGACCAATGGGGACGGTGTGTCACCTGCCAACGGTGTGGTCCTGG
  ACAGGAGCTATCCAAGGATTGTGGTTATGGAGAGGGTGGAGATGCCTACTGCACAGCCTG
  CCCTCCTCGCAGGTACAAAAGCAGCTGGGGCCACCACAGATGTCAGAGTTGCATCACCTG
  TGCTGTCATCAATCGTGTTCAGAAGGTCAACTGCACAGCTACCTCTAATGCTGTCTGTGG
  GGACTGTTTGCCCAGGTTCTACCGAAAGACACGCATTGGAGGCCTGCAGGACCAAGAGTG
  CATCCCGTGCACGAAGCAGACCCCCACCTCTGAGGTTCAATGTGCCTTCCAGTTGAGCTT
  AGTGGAGGCAGATGCACCCACAGTGCCCCCTCAGGAGGCCACACTTGTTGCACTGGTGAG
  CAGCCTGCTAGTGGTGTTTACCCTGGCCTTCCTGGGGCTCTTCTTCCTCTACTGCAAGCA
  GTTCTTCAACAGACATTGCCAGCGTGGAGGTTTGCTGCAGTTTGAGGCTGATAAAACAGC
  ANAGGAGGAATCTCTCTTCCCCGTGCCACCCAGCAAGGAGACCAGTGCTGAGTCCCAAGT
  GAGTGAGAACATCTTTCAGACCCAGCCACTTAACCCTATCCTCGAGGACGACTGCAGCTC
  GACTAGTGGCTTCCCACACAGGAGTCCTTTACCATGGCCTCCTGCACCTCAGAGAGCCAC
  TCCACTGGGTCCACAGCCCCATCGAATGCACAGAGCTGGACCTGCAAAAGTTTCCAGCTC
  TGCCTCCTATACTGGAGCTGAGACCTGGGGGGGAACACAT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_021783
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_021783.2, NP_068555.1
• RefSeq Size: 3385 bp
• RefSeq ORF: 894 bp
• Locus ID: 60401
• UniProt ID: Q9HAV5
• Cytogenetics: Xq12
• Protein Families: Druggable Genome, Transcription Factors, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction
• Gene Summary: The protein encoded by this gene is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily, and contains cysteine-rich repeats and a single transmembrane domain. This protein binds to the EDA-A2 isoform of ectodysplasin, which plays an important role in maintenance of hair and teeth. Alternatively spliced transcript variants encodes distinct protein isoforms. [provided by RefSeq, Apr 2016]