Kv beta 1 (KCNAB1) (NM_003471) Human Untagged Clone
KCNAB1 (untagged)-Human potassium voltage-gated channel, shaker-related subfamily, beta member 1 (KCNAB1), transcript variant 2
|Product Name||Kv beta 1 (KCNAB1) (NM_003471) Human Untagged Clone|
|Type||Human Untagged Clone|
|Synonyms||AKR6A3; hKvb3; hKvBeta3; KCNA1B; KV-BETA-1; Kvb1.3|
|E. coli Selection||Ampicillin (100 ug/mL)|
>OriGene ORF sequence for NM_003471 edited
>OriGene 5' read for NM_003471 unedited
|Insert Size||4000 bp|
|OTI Disclaimer||Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).|
|Product Components||The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.|
|Reconstitution||1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
|RefSeq Size||3301 bp|
|RefSeq ORF||1227 bp|
|Protein Families||Druggable Genome, Ion Channels: Other|
|Gene Summary||Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member includes distinct isoforms which are encoded by alternatively spliced transcript variants of this gene. Some of these isoforms are beta subunits, which form heteromultimeric complexes with alpha subunits and modulate the activity of the pore-forming alpha subunits. [provided by RefSeq, Apr 2015]
Transcript Variant: This variant (2) has an alternate 5' sequence including the 5' UTR and the 5' coding region, as compared to variant 1. It encodes isoform 2, also known as kvb1.2, which has a shorter and distinct N-terminus than isoform 1.
|cDNA Clone Resources|
|RC215331||KCNAB1 (Myc-DDK-tagged)-Human potassium voltage-gated channel, shaker-related subfamily, beta member 1 (KCNAB1), transcript variant 2||
|RG215331||KCNAB1 (GFP-tagged) - Human potassium voltage-gated channel, shaker-related subfamily, beta member 1 (KCNAB1), transcript variant 2||
|RC215331L3||Lenti ORF clone of Human potassium voltage-gated channel, shaker-related subfamily, beta member 1 (KCNAB1), transcript variant 2, Myc-DDK-tagged||
|RC215331L4||Lenti ORF clone of Human potassium voltage-gated channel, shaker-related subfamily, beta member 1 (KCNAB1), transcript variant 2, mGFP tagged||