Kv beta 1 (KCNAB1) (NM_003471) Human Untagged Clone

CAT#: SC123984

KCNAB1 (untagged)-Human potassium voltage-gated channel, shaker-related subfamily, beta member 1 (KCNAB1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: Kv beta 1
• Synonyms: AKR6A3; hKvb3; hKvBeta3; KCNA1B; KV-BETA-1; Kvb1.3
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_003471 edited
  ATGCATCTGTATAAACCTGCCTGTGCAGACATCCCGAGCCCCAAGCTGGGTCTGCCAAAA
  TCCAGTGAATCGGCTCTAAAATGTAGATGGCACCTAGCAGTGACCAAGACTCAGCCTCAG
  GCGGCCTGCAAACCTGTGAGGCCCAGTGGAGCAGCCGAACAGAAATATGTGGAAAAGTTT
  CTACGTGTTCATGGAATTTCGTTGCAGGAAACCACCAGAGCAGAGACGGGCATGGCATAC
  AGGAATCTTGGAAAATCAGGACTCAGAGTTTCTTGCTTGGGTCTTGGAACATGGGTGACA
  TTTGGAGGTCAAATTTCAGATGAGGTTGCTGAACGGCTGATGACCATCGCCTATGAAAGT
  GGTGTTAACCTCTTTGATACTGCCGAAGTCTATGCTGCTGGAAAGGCTGAAGTGATTCTG
  GGGAGCATCATCAAGAAGAAAGGCTGGAGGAGGTCCAGTCTGGTCATAACAACCAAACTC
  TACTGGGGTGGAAAAGCTGAAACAGAAAGAGGGCTGTCAAGAAAGCATATTATTGAAGGA
  TTGAAGGGCTCCCTCCAGAGGCTGCAGCTCGAGTATGTGGATGTGGTCTTTGCAAATCGA
  CCGGACAGTAACACTCCCATGGAAGAAATTGTCCGAGCCATGACACATGTGATAAACCAA
  GGCATGGCGATGTACTGGGGCACCTCGAGATGGAGTGCTATGGAGATCATGGAAGCCTAT
  TCTGTAGCAAGACAGTTCAATATGATCCCACCGGTCTGTGAACAAGCTGAGTACCATCTT
  TTCCAGAGAGAGAAAGTGGAGGTCCAGCTGCCAGAGCTCTACCACAAAATAGGTGTTGGC
  GCAATGACATGGTCTCCACTTGCCTGTGGAATCATCTCAGGAAAATACGGAAACGGGGTG
  CCTGAAAGTTCCAGGGCTTCACTGAAGTGCTACCAGTGGTTGAAAGAAAGAATTGTAAGT
  GAAGAAGGGAGAAAACAGCAAAACAAGCTAAAAGACCTTTCCCCAATTGCGGAGCGTCTG
  GGATGCACACTACCTCAGCTAGCTGTTGCGTGGTGCCTGAGAAATGAAGGTGTGAGTTCT
  GTGCTCCTGGGATCATCCACTCCTGAACAACTCATTGAAAACCTTGGTGCCATTCAGGTT
  CTCCCAAAGATGACATCACATGTGGTAAATGAGATTGATAACATACTGCGCAACAAGCCC
  TACAGCAAGAAGGACTATAGATCATAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003471 unedited
  AGTTCGAATTTGTATACGACTCATATAGGGCGGCCGCGAATTCGCACCAGCGGGAACTTA
  GGAGCCTGCTCGCCTAAAAATGATAAGAGAGATCTAAAGAAAACAAGCTAAACCTTTTGA
  GGGACATACTGAAGCCAGATAACCCAAGGTATTCACAGCAAGATACAGTGAGTCTTAAAG
  TTAAGCACCGTGCAATTAGCTTTGCTTCCTTGGGTTTTTGAAACATGCATCTGTATAAAC
  CTGCCTGTGCAGACATCCCGAGCCCCAAGCTGGGTCTGCCAAAATCCAGTGAATCGGCTC
  TAAAATGTAGATGGCACCTAGCAGTGACCAAGACTCAGCCTCAGGCGGCCTGCAAACCTG
  TGAGGCCCAGTGGAGCAGCCGAACAGAAATATGTGGAAAAGTTTCTACGTGTTCATGGAA
  TTTCGTTGCAGGAAACCACCAGAGCAGAGACGGGCATGGCATACAGGAATCTTGGAAAAT
  CANGACTCAGAGTTTCTTGCTTGGGTCTTGGAACATGGGTGACATTTGGAGGTCAAATTT
  CAGATGANGTTGCTGAACGGCTGATGACCATCGCCTATGAAAGTGGTGTTAACCTCTTTG
  ATACTGCCGAAATCTATGCTGCTGGGAAGGCTGAAGTGATTCTGGGGAGCATCATCAAGA
  AGAAAGGGCTGGAGGAGTCCAGTCTGGTCATAACACCCAAACTCTACTGGGGTGGAAAAG
  CTNGAACAGAAAGAGGGCTGTCAAGAAAGCATATTATTGAAAGGATGAAGGGCTCCCTCC
  AAAGCTGCANNCTCAGTATGTGGATGTGGTCTTTGCAAATCGACCGCCAGTAACCCTCCC
  ATGGAAGAAATTTTCCAACCATGAACATGTGGATAAACAAGCCATGGCGATGTCTTGGGG
  CACCCCGGAAGGATGCTTGGG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_003471
• Insert Size: 4000 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_003471.2, NP_003462.2
• RefSeq Size: 3301 bp
• RefSeq ORF: 1227 bp
• Locus ID: 7881
• UniProt ID: Q14722
• Cytogenetics: 3q25.31
• Domains: aldo_ket_red
• Protein Families: Druggable Genome, Ion Channels: Other
• Gene Summary: Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member includes distinct isoforms which are encoded by alternatively spliced transcript variants of this gene. Some of these isoforms are beta subunits, which form heteromultimeric complexes with alpha subunits and modulate the activity of the pore-forming alpha subunits. [provided by RefSeq, Apr 2015]
  Transcript Variant: This variant (2) has an alternate 5' sequence including the 5' UTR and the 5' coding region, as compared to variant 1. It encodes isoform 2, also known as kvb1.2, which has a shorter and distinct N-terminus than isoform 1.