Follistatin (FST) (BC004107) Human Untagged Clone

CAT#: SC123768

FST (untagged)-Human follistatin, transcript variant FST344 (cDNA clone MGC:10663 IMAGE:3688745), complete cds

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: Follistatin
• Synonyms: follistatin; follistatin isoform FST317; FS
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for BC004107 edited
  CCCCCGTCTAGATTTAAAGCGCGGCTGCGCCCGGCTTCTGACGTCCATTGAATCGCGCGG
  GCGGCCGGCGGCGAGCGCGGGGCTGCGCCGGGATCGCTGCGCCCTCCGCCGCTGGCCTCT
  GCGACGCGCGCCGCTCGCCCGAGCCACCCGCCGCCGCGCCGGCTCCCCGCGCCGCTGCGC
  TCCTCGCCCCGCGCCTGCCCCCAGGATGGTCCGCGCGAGGCACCAGCCGGGTGGGCTTTG
  CCTCCTGCTGCTGCTGCTCTGCCAGTTCATGGAGGACCGCAGTGCCCAGGCTGGGAACTG
  CTGGCTCCGTCAAGCGAAGAACGGCCGCTGCCAGGTCCTGTACAAGACCGAACTGAGCAA
  GGAGGAGTGCTGCAGCACCGGCCGGCTGAGCACCTCGTGGACCGAGGAGGACGTGAATGA
  CAACACACTCTTCAAGTGGATGATTTTCAACGGGGGCGCCCCCAACTGCATCCCCTGTAA
  AGAAACGTGTGAGAACGTGGACTGTGGACCTGGGAAAAAATGCCGAATGAACAAGAAGAA
  CAAACCCCGCTGCGTCTGCGCCCCGGATTGTTCCAACATCACCTGGAAGGGTCCAGTCTG
  CGGGCTGGATGGGAAAACCTACCGCAATGAATGTGCACTCCTAAAGGCAAGATGTAAAGA
  GCAGCCAGAACTGGAAGTCCAGTACCAAGGCAGATGTAAAAAGACTTGTCGGGATGTTTT
  CTGTCCAGGCAGCTCCACATGTGTGGTGGACCAGACCAATAATGCCTACTGTGTGACCTG
  TAATCGGATTTGCCCAGAGCCTGCTTCCTCTGAGCAATATCTCTGTGGGAATGATGGAGT
  CACCTACTCCAGTGCCTGCCACCTGAGAAAGGCTACCTGCCTGCTGGGCAGATCTATTGG
  ATTAGCCTATGAGGGAAAGTGTATCAAAGCAAAGTCCTGTGAAGATATCCAGTGCACTGG
  TGGGAAAAAATGTTTATGGGATTTCAAGGTTGGGAGAGGCCGGTGTTCCCTCTGTGATGA
  GCTGTGCCCTGACAGTAAGTCGGATGAGCCTGTCTGTGCCAGTGACAATGCCACTTATGC
  CAGCGAGTGTGCCATGAAGGAAGCTGCCTGCTCCTCAGGTGTGCTACTGGAAGTAAAGCA
  CTCCGGATCTTGCAACTCCATTTCGGAAGACACCGAGGAAGAGGAGGAAGATGAAGACCA
  GGACTACAGCTTTCCTATATCTTCTATTCTAGAGTGGTAAACTCTCTATAAGTGTTCAGT
  GTTGACATAGCCTTTGTGCAAAAAAAAAAAAAAAAAAAAAAAAAAAGAAAAAAAAAAAAA
  AAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for BC004107 unedited
  CCGGGTAACCNGTTGGTNTAGTAAACCGNACTCACTGTNAGGNCGTGCCGCGNAATTCGG
  CACGAGGCCCCCGTCTTGATTTAAAGCGCGGCTGCGCCCGGCTTCTGACGTCCATTGAAT
  CGCGCGGGCGGACGGCGGCGAGCGCGGGGCTGCGCCGGGATCGCTGCGCCCTCCGCCGCT
  GGCCTCTGCGACGCGCGCCGCTCGCCCGAGCCACCCGCCGCCGTGCCGGCTCCCCGCGCC
  GCTGCGCTCCTCGCCCCGCGCCTGCCCCCAGGATGGTCCGCGCGAGGCACCAGCCGGGTG
  GGCTTTGCCTCCTGCTGCTGCTGCTCTGCCAGTTCATGGAGGACCGCAGTGCCCAGGCTG
  GGAACTGCTGGCTCCGTCAAGCGAAGAACGGCCGCTGCCAGGTCCTGTACAAGACCGAAC
  TGAGCAAGGAGGAGTGCTGCAGCACCGGCCGGCTGAGCACCTCGTGGACCGAGGAGGACG
  TGAATGACAACACACTCTTCAAGTGGATGATTTTCAACGGGGGCGCCCCCAACTGCATCC
  CCTGTAAAGAAACGTGTGAGAACGTGGACTGTGGACCTGGGAAAAAATGCCGAATGAACA
  AGAAGAACAAACCCCGCTGCGTCTGCGCCCCGGATTGTTCCAACATCACCTGGAAGGGTC
  CAGTCTGCGGGCTGGATGGGAAAACCTACCGCAATGAATGTGCACTCCTAAAGGCGAGAT
  GTAAAGAGCAGCCAGGACTGGAAGTCCAGTACCATAGCAGATGTAAAAAGACTTGTCGGG
  ATGTTTTCTGTCCAGGCAGCTCCACATGTGTGGTGGACCAGACCAATAATGCCTACTGTG
  TGACCCTGTATCGGATGTGCCCAGAGCCTGCTTGCTCTGAGCATATCTCTGTGGGATGAT
  GCAGTCACTACTGCAGTGCCTGCCACCTGGN
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for BC004107 unedited
  TCCCCCAAATTACTGTGNACCGCGGCCGCTATACTANGATCGNGTTTTTTTTTTTTTTTT
  TTTCTTTTTTTTTTTTTTTTTTTTTTTTTTTGCACAAGGCTATGTCAACACTGGAACACT
  TATAGAGAGTTTACCACTCTTAGAATAGAAGAATAGGGAAAGCTGTAGTCCTGGTCTTCA
  TCTTCCTCCTCTTCCTCGGGGTCTTCCGAAATGGAGTTGCAAGATCCGGAGTGCTTTACT
  TCCAGTAGCACACCTGAGGAGCAGGCAGCTTCCTTCATGGGACACTCGCTGGCATAAGTG
  GCATTGTCACTGGCACAAACAGGCTCATCCGACTTACTGTCAGGGCACAGCTCATCACAG
  AGGGAACACCGGCCTCTCCCAACCTTGAAATCCCATAAACATTTTTTCCCACCAGTGCAC
  TGGATATCTTCACAGGACTTTGCTTTGATACACTTTCCCTCATAGGCTAATCCAATAGAT
  CTGCCCAGCAGGCAGGTAGCCTTTCTCAGGTGGCAGGCACTGGAGTAGGTGACTCCATCA
  TTCCCACAGAGATATTGCTCAAAGGAAGCAGGCTCTGGGCAAATCCGATTACAGGTCACA
  CAGTAGGCATTATTGGTCTGGTCCACCACACATGTGGAGCTGCCTGGACAGAAAAATCCC
  GACAAGTCTTTTTACATCTGCCTTGGTACTGGACTTCCAGTTTTGGCTGCTCTTTACATC
  TTGCCTTTTAGAGTGCACATTCATTGCGGGAGGTTTTCCCATCCAGCCCGCAAACTGGAC
  CCTTCCAGTGATGTTGGGACAATCCGGGGCGCACACCCAACGGAGGTTGGTCCTCTTGGT
  CAATCCGGCATTTTTCCCAGTGCACAATC
  
• Restriction Sites: Please inquire
• ACCN: BC004107
• Insert Size: 1335 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC004107.2, AAH04107.1
• RefSeq Size: 1326 bp
• Locus ID: 10468
• Cytogenetics: 5q11.2
• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: TGF-beta signaling pathway
• Gene Summary: Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release. The single FST gene encodes two isoforms, FST317 and FST344 containing 317 and 344 amino acids respectively, resulting from alternative splicing of the precursor mRNA. In a study in which 37 candidate genes were tested for linkage and association with polycystic ovary syndrome (PCOS) or hyperandrogenemia in 150 families, evidence was found for linkage between PCOS and follistatin. [provided by RefSeq, Jul 2008]