SIRT6 (NM_016539) Human Untagged Clone

CAT#: SC123758

SIRT6 (untagged)-Human sirtuin 6 (SIRT6), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SIRT6
• Synonyms: SIR2L6
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_016539 edited
  AGGATGTCGGTGAATTACGCGGCGGGGCTGTCGCCGTACGCGGACAAGGGCAAGTGCGGC
  CTCCCGGAGATCTTCGACCCCCCGGAGGAGCTGGAGCGGAAGGTGTGGGAACTGGCGAGG
  CTGGTCTGGCAGTCTTCCAGTGTGGTGTTCCACACGGGTGCCGGCATCAGCACTGCCTCT
  GGCATCCCCGACTTCAGGGGTCCCCACGGAGTCTGGACCATGGAGGAGCGAGGTCTGGCC
  CCCAAGTTCGACACCACCTTTGAGAGCGCGCGGCCCACGCAGACCCACATGGCGCTGGTG
  CAGCTGGAGCGCGTGGGCCTCCTCCGCTTCCTGGTCAGCCAGAACGTGGACGGGCTCCAT
  GTGCGCTCAGGCTTCCCCAGGGACAAACTGGCAGAGCTCCACGGGAACATGTTTGTGGAA
  GAATGTGCCAAGTGTAAGACGCAGTACGTCCGAGACACAGTCGTGGGCACCATGGGCCTG
  AAGGCCACGGGCCGGCTCTGCACCGTGGCTAAGGCAAGGGGGCTGCGAGCCTGCAGGGGA
  GAGCTGAGGGACACCATCCTAGACTGGGAGGACTCCCTGCCCGACCGGGACCTGGCACTC
  GCCGATGAGGCCAGCAGGAACGCCGACCTGTCCATCACGCTGGGTACATCGCTGCAGATC
  CGGCCCAGCGGGAACCTGCCGCTGGCTACCAAGCGCCGGGGAGGCCGCCTGGTCATCGTC
  AACCTGCAGCCCACCAAGCACGACCGCCATGCTGACCTCCGCATCCATGGCTACGTTGAC
  GAGGTCATGACCCGGCTCATGAAGCACCTGGGGCTGGAGATCCCCGCCTGGGACGGCCCC
  CGTGTGCTGGAGAGGGCGCTGCCACCCCTGCCCCGCCCGCCCACCCCCAAGCTGGAGCCC
  AAGGAGGAATCTCCCACCCGGATCAACGGCTCTATCCCCGCCGGCCCCAAGCAGGAGCCC
  TGCGCCCAGCACAACGGCTCAGAGCCCGCCAGCCCCAAACGGGAGCGGCCCACCAGCCCT
  GCCCCCCACAGACCCCCCAAAAGGGTGAAGGCCAAGGCGGTCCCCAGCTGACCAGGGTGC
  TTGGGGAGGGTGGGGCTTTTTGTAGAAACTGTGGATTCTTTTTCTCTCGTGGTCTCACTT
  TGTTACTTGTTTCTGTCCCCGGGAGCCTCAGGGCTCTGAGAGCTGTGCTCCAGGCCAGGG
  GTTACACCTGCCCTCCGTGGTCCCTCCCTGGGCTCCAGGGGCCTCTGGTGCGGTTCCGGG
  AAGAAGCCACACCCCAGAGGTGACAGCTGAGCCCCTGCCACACCCCAGCCTCTGACTTGC
  TGTGTTGTCCAGAGGTGAGGCTGGGCCCTCCCTGGTCTCCAGCTTAAACAGGAGTGAACT
  CCCTCTGTCCCCAGGGCCTCCCTTCTGGGCCCCCTACAGCCCACCCTACCCCTCCTCCAT
  GGGCCCTGCAGGAGGGGAGACCCACCTTGAAGTGGGGGATCAGTAGAGGCTTGCACTGCC
  TTTGGGGCTGGAGGGAGACGTGGGTCCACCAGGCTTCTGGAAAAGTCCTCAATGCAATAA
  AAACAATTTCTTTCTTGCAAAAAAAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_016539 unedited
  GGACCTTGGTTTTGTATACGACTTATATAGGGCGGCCGCGAATTCGCACGAGGAGGATGT
  CGGTGAATTACGCGGCGGGGCTGTCGCCGTACGCGGACAAGGGCAAGTGCGGCCTCCCGG
  AGATCTTCGACCCCCCGGAGGAGCTGGAGCGGAAGGTGTGGGAACTGGCGAGGCTGGTCT
  GGCAGTCTTCCAGTGTGGTGTTCCACACGGGTGCCGGCATCAGCACTGCCTCTGGCATCC
  CCGACTTCAGGGGTCCCCACGGAGTCTGGACCATGGAGGAGCGAGGTCTGGCCCCCAAGT
  TCGACACCACCTTTGAGAGCGCGCGGCCCACGCAGACCCACATGGCGCTGGTGCAGCTGG
  AGCGCGTGGGCCTCCTCCGCTTCCTGGTCAGCCAGAACGTGGACGGGCTCCATGTGCGCT
  CAGGCTTCCCCAGGGACAAACTGGCAGAGCTCCACGGGAACATGTTTGTGGAAGAATGTG
  CCAAGTGTAAGACGCAGTACGTCCGAGACACAGTCGTGGGCACCATGGGCCTGAAGGCCA
  CGGGCCGGCTCTGCACCGTGGCTAAGGCAAGGGGGCTGCGAGCCTGCAGGGGAGAGCTGA
  GGGACACCATCCTAGACTGGGAGGACTCCCTGCCCGACCGGGACCTGGCACTCGCCGATG
  AGGCCAGCAGGAACGCCGACCTGTCCATCACGCTGGGTACATCGCTGCAGATCCGGCCCA
  GCGGGAACCTGCCGCTGGCTACCAAGCGCCGGGGAGGCCGCCTGGTCATCGTCAACCTGC
  AGCCCACCAAGCACGACCGCCATGCTGACCTCCGCATCCATGGCTACGTTGACGAGGGTC
  ATGACCCGCTCATGAAGCACCTGGGGCTGGAGATCCCCGCCTGGGACNGCCCCCGTGTGC
  TGGAGAGGGCGCTNGCACCCCTGCCCCCGCCGNCCACCC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_016539 unedited
  NAATTAGAAACAGTTTTTATTGCATTGNAGACTTTTCCAGAACCTGGTGGACCCACGTCT
  CCCTCCAGCCCCAAAGCAGTGCAAGCCTCTACTGATCCCCCACTTCAGGTGGGTCTCCCC
  TCCTGCAGGGCCCATGGAGGAGGGGTAGGGTGGGCTGTAGGGGGCCCAGAAGGGAGGCCC
  TGGGGACAGAGGGAGTTCACTCCTGTTTAAGCTGGAGACCAGGGAGGGCCCAGCCTCACC
  TCTGGACAACACAGCAAGTCAGAGGCTGGGGTGTGGCAGGGGCTCAGCTGTCACCTCTGG
  GGTGTGGCTTCTTCCCGGAACCGCACCAGAGGCCCCTGGAGCCCAGGGAGGGACCACGGA
  GGGCAGGTGTAACCCCTGGCCTGGAGCACAGCTCTCAGAGCCCTGAGGCTCCCGGGGACA
  GAAACAAGTAACAAAGTGAGACCACGAGAGAAAAAGAATCCACAGTTTCTACAAAAAGCC
  CCACCCTCCCCAAGCACCCTGGTCAGCTGGGGACCGCCTTGGCCTTCACCCTTTTGGGGG
  GTCTGTGGGGGGCAGGGCTGGTGGGCCGCTCCCGTTTGGGGCTGGCGGGCTCTGAGCCGT
  TGTGCTGGGCGCAGGGCTCCTGCTTGGGGCCGGCGGGGATAGAGCCGTTGATCCGGGTGG
  GAGATTCCTCCTTGGGCTCCAGCTTGGGGGTGGGCGGGCGGGGCAGGGGTGGCAGCGCCC
  TCTCCAGCACACGGGGGCCGTCCCAGGCGGGGATCTCCAGCCCCCAGTGCTTTCATGACC
  GGGTCATGACCTCGTCAACGTACCCTTGGATGCCGAAGTCAACCTGGCCGTCGTGCTTGG
  TTGGCTGCCGGTTGACAATGACCCAGCGCCCCCCCGGCGCTTTGTAGCCAGCGGCAGGTT
  CCG
  
• Restriction Sites: Please inquire
• ACCN: NM_016539
• Insert Size: 1600 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_016539.1, NP_057623.1
• RefSeq Size: 1638 bp
• RefSeq ORF: 1068 bp
• Locus ID: 51548
• UniProt ID: Q8N6T7
• Cytogenetics: 19p13.3
• Protein Families: Druggable Genome, Transcription Factors
• Gene Summary: This gene encodes a member of the sirtuin family of NAD-dependent enzymes that are implicated in cellular stress resistance, genomic stability, aging and energy homeostasis. The encoded protein is localized to the nucleus, exhibits ADP-ribosyl transferase and histone deacetylase activities, and plays a role in DNA repair, maintenance of telomeric chromatin, inflammation, lipid and glucose metabolism. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016]