ROR gamma (RORC) (NM_005060) Human Untagged Clone

CAT#: SC121242

RORC (untagged)-Human RAR-related orphan receptor C (RORC), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RORC
• Synonyms: IMD42; NR1F3; RORG; RZR-GAMMA; RZRG; TOR
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC121242 sequence for NM_005060 edited (data generated by NextGen Sequencing)
  ATGGACAGGGCCCCACAGAGACAGCACCGAGCCTCACGGGAGCTGCTGGCTGCAAAGAAG
  ACCCACACCTCACAAATTGAAGTGATCCCTTGCAAAATCTGTGGGGACAAGTCGTCTGGG
  ATCCACTACGGGGTTATCACCTGTGAGGGGTGCAAGGGCTTCTTCCGCCGGAGCCAGCGC
  TGTAACGCGGCCTACTCCTGCACCCGTCAGCAGAACTGCCCCATCGACCGCACCAGCCGA
  AACCGATGCCAGCACTGCCGCCTGCAGAAATGCCTGGCGCTGGGCATGTCCCGAGATGCT
  GTCAAGTTCGGCCGCATGTCCAAGAAGCAGAGGGACAGCCTGCATGCAGAAGTGCAGAAA
  CAGCTGCAGCAGCGGCAACAGCAGCAACAGGAACCAGTGGTCAAGACCCCTCCAGCAGGG
  GCCCAAGGAGCAGATACCCTCACCTACACCTTGGGGCTCCCAGACGGGCAGCTGCCCCTG
  GGCTCCTCGCCTGACCTGCCTGAGGCTTCTGCCTGTCCCCCTGGCCTCCTGAAAGCCTCA
  GGCTCTGGGCCCTCATATTCCAACAACTTGGCCAAGGCAGGGCTCAATGGGGCCTCATGC
  CACCTTGAATACAGCCCTGAGCGGGGCAAGGCTGAGGGCAGAGAGAGCTTCTATAGCACA
  GGCAGCCAGCTGACCCCTGACCGATGTGGACTTCGTTTTGAGGAACACAGGCATCCTGGG
  CTTGGGGAACTGGGACAGGGCCCAGACAGCTACGGCAGCCCCAGTTTCCGCAGCACACCG
  GAGGCACCCTATGCCTCCCTGACAGAGATAGAGCACCTGGTGCAGAGCGTCTGCAAGTCC
  TACAGGGAGACATGCCAGCTGCGGCTGGAGGACCTGCTGCGGCAGCGCTCCAACATCTTC
  TCCCGGGAGGAAGTGACTGGCTACCAGAGGAAGTCCATGTGGGAGATGTGGGAACGGTGT
  GCCCACCACCTCACCGAGGCCATTCAGTACGTGGTGGAGTTCGCCAAGAGGCTCTCAGGC
  TTTATGGAGCTCTGCCAGAATGACCAGATTGTGCTTCTCAAAGCAGGAGCAATGGAAGTG
  GTGCTGGTTAGGATGTGCCGGGCCTACAATGCTGACAACCGCACGGTCTTTTTTGAAGGC
  AAATACGGTGGCATGGAGCTGTTCCGAGCCTTGGGCTGCAGCGAGCTCATCAGCTCCATC
  TTTGACTTCTCCCACTCCCTAAGTGCCTTGCACTTTTCCGAGGATGAGATTGCCCTCTAC
  ACAGCCCTTGTTCTCATCAATGCCCATCGGCCAGGGCTCCAAGAGAAAAGGAAAGTAGAA
  CAGCTGCAGTACAATCTGGAGCTGGCCTTTCATCATCATCTCTGCAAGACTCATCGCCAA
  AGCATCCTGGCAAAGCTGCCACCCAAGGGGAAGCTTCGGAGCCTGTGTAGCCAGCATGTG
  GAAAGGCTGCAGATCTTCCAGCACCTCCACCCCATCGTGGTCCAAGCCGCTTTCCCTCCA
  CTCTACAAGGAGCTCTTCAGCACTGAAACCGAGTCACCTGTGGGGCTGTCCAAGTGA
  
  Clone variation with respect to NM_005060.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_005060 unedited
  TTCCCCCAATTTCGGGATTTGNTAAACGATCTCACTATAGGGCGGCCGCGATTCCCGGGA
  TCAGGACGGCACCAAGGGAGCTGCCCCATGGACAGGGCCCCACAGAGACAGCACCGAGCC
  TCACGGGAGCTGCTGGCTGCAAAGAAGACCCACACCTCACAAATTGAAGTGATCCCTTGC
  AAAATCTGTGGGGACAAGTCGTCTGGGATCCACTACGGGGTTATCACCTGTGAGGGGTGC
  AAGGGCTTCTTCCGCCGGAGCCAGCGCTGTAACGCGGCCTACTCCTGCACCCGTCAGCAG
  AACTGCCCCATCGACCGCACCAGCCGAAACCGATGCCAGCACTGCCGCCTGCAGAAATGC
  CTGGCGCTGGGCATGTCCCGAGATGCTGTCAAGTTCGGCCGCATGTCCAAGAAGCAGAGG
  GACAGCCTGCATGCAGAAGTGCAGAAACAGCTGCAGCAGCGGCAACAGCAGCAACAGGAA
  CCAGTGGTCAAGACCCCTCCAGCAGGGGCCCAAGGAGCAGATACCCTCACCTACACCTTG
  GGGCTCCCAGACGGGCAGCTGCCCCTGGGCTCCTCGCCTGACCTGCCTGAGGCTTCTGCC
  TGTCCCCCTGGCCTCCTGAAAGCCTCAGGCTCTGGGCCCTCATATTCCAACAACTTGGCC
  AAGGCAGGGCTCAATGGGGCCTCATGCCACCTTGAATACAGCCCTGAGCGGGGCAAGGCT
  GAGGGCAGAGAGAGCTTCTATAGCACAGGCAGCCAGCTGACCCCTGACCGATGTGGACTT
  CGTTTTGAGGAACACAGGCATCCTGGGCTTGGNGAACTGGGACAGGGCCCAGACAGCTAC
  CGCAGCCCCAGTTTCCGCAGCACACCGGAGG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_005060 unedited
  NGGGACATTCCGGTATCATTTTCTACATTTCCTTNAGGGGCTCTCACTGCCAGTCTCTGA
  GCTTGATCCATCTCCCCAAGCCGAAGCCCAAAGGGAAATGCAATGAGGTATTTCAAAGGC
  TTATTCTTAGCTTCTGAGCTTCTGAATGAATTGCATTCTATTCATCCAGGGAGCCCTGGA
  TGCCCCTGTTTTCTTGAGGATGTCTTGGTCCCCCAGAAGTCCTTAAATCCCAGCCACCCC
  ATGCCTTCCAGAAACTGGGTGTGAAGGAATATGGGAAATGAGATCAGGTCAAAGCTGAGG
  CTGGAGATGGTGTTCTGCCAGCCCCACCCTCTGGCGATTGTCCCACTGCCAGGCCGGCCT
  GCTGACAGAAAGCCAGCCGCAGCATCTGCTCACTTCCAAAGAGCTGGTGGGGACCACCCT
  CCAGGGTTCATGGGAAAGGAAAAGGGTGAGGGTGGAACGGGGTCCAGGGAGGTGGGCCAG
  CAGGCCATAGGGAGAGGCAAGGAGTCCCTCTTCCAGGTCACTTGGACAGCCCCACAGGTG
  ACTCGGTTTCAGTGCTGAAGAGCTCCTTGTAGAGTGGAGGGAAAGCGGCTTGGACCACGA
  TGGGGTGGAGGTGCTGGAAGATCTGCAGCCTTTCCACATGCTGGCTACACAGGCTATCGA
  AGCTTCCCCTTGGGTGGCAGCTTTGCCAGGATGCTTTGGCGATGAGTCTTGCCTAAATGA
  TGATGAAAGGCCAGCTCCCGAATGGACTGCAACTGTTTTACTTTCCTTTCCTCTTGGAAG
  CCTGCCCGATGGGCCATTGAGAGAACCAAGGCTGGGTAAAGGGCAATCTATTCCTCGAAA
  ATGCAAGGCACTTAGGGACTGGAAAAATCAATAAGGAGCTGATGAGCTCCCTCCACCCAA
  GGCTCG
  
• Restriction Sites: Please inquire
• ACCN: NM_005060
• Insert Size: 1950 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_005060.3, NP_005051.2
• RefSeq Size: 3084 bp
• RefSeq ORF: 1557 bp
• Locus ID: 6097
• UniProt ID: P51449
• Cytogenetics: 1q21.3
• Protein Families: Druggable Genome, Transcription Factors
• Gene Summary: The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known; however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).