Ferritin Light Chain (FTL) (NM_000146) Human Untagged Clone

SKU SC120074

FTL (untagged)-Human ferritin, light polypeptide (FTL)

Product Data

• Type: Human Untagged Clone
• Target Symbol: Ferritin Light Chain
• Synonyms: LFTD; NBIA3
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_000146, the custom clone sequence may differ by one or more nucleotides; ; ; GGAATTCGGCACGAGGCTCGGCCATCTCCTGCTTCTGGGACCTGCCAGCACCGTTTTTGTGGTTAGCTCC; TTCTTGCCAACCAACCATGAGCTCCCAGATTCGTCAGAATTATTCCACCGACGTGGAGGCAGCCGTCAAC; AGCCTGGTCAATTTGTACCTGCAGGCCTCCTACACCTACCTCTCTCTGGGCTTCTATTTCGACCGCGATG; ATGTGGCTCTGGAAGGCGTGAGCCACTTCTTCCGCGAACTGGCCGAGGAGAAGCGCGAGGGCTACGAGCG; TCTCCTGAAGATGCAAAACCAGCGTGGCGGCCGCGCTCTCTTCCAGGACATCAAGAAGCCAGCTGAAGAT; GAGTGGGGTAAAACCCCAGACGCCATGAAAGCTGCCATGGCCCTGGAGAAAAAGCTGAACCAGGCCCTTT; TGGATCTTCATGCCCTGGGTTCTGCCCGCACGGACCCCCATCTCTGTGACTTCCTGGAGACTCACTTCCT; AGATGAGGAAGTGAAGCTTATCAAGAAGATGGGTGACCACCTGACCAACCTCCACAGGCTGGGTGGCCCG; GAGGCTGGGCTGGGCGAGTATCTCTTCGAAAGGCTCACTCTCAAGCACGACTAAGAGCCTTCTGAGCCCA; GCGACTTCTGAAGGGCCCCTTGCAAAGTAATAGGGCTTCTGCCTAAGCCTCTCCCTCCAGCCAATAGGCA; GCTTTCTTAACTATCCTAACAAGCCTTGGACCAAATGGAAATAAAGCTTTTTGATGCAAAAAAAAAAAAA; AAAAAA; ;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_000146 unedited; CCCCCCGTTAGAATTGTATACGACTCATATAGGCGGCCGCGAAATTCGCACGAGGCTCGG; CCATCTCCTGCTTCTGGGACCTGCCAGCACCGTTTTTGTGGTTAGCTCCTTCTTGCCAAC; CAACCATGAGCTCCCAGATTCGTCAGAATTATTCCACCGACGTGGAGGCAGCCGTCAACA; GCCTGGTCAATTTGTACCTGCAGGCCTCCTACACCTACCTCTCTCTGGGCTTCTATTTCG; ACCGCGATGATGTGGCTCTGGAAGGCGTGAGCCACTTCTTCCGCGAACTGGCCGAGGAGA; AGCGCGAGGGCTACGAGCGTCTCCTGAAGATGCAAAACCAGCGTGGCGGCCGCGCTCTCT; TCCAGGACATCAAGAAGCCAGCTGAAGATGAGTGGGGTAAAACCCCAGACGCCATGAAAG; CTGCCATGGCCCTGGAGAAAAAGCTGAACCAGGCCCTTTTGGATCTTCATGCCCTGGGTT; CTGCCCGCACGGACCCCCATCTCTGTGACTTCCTGGAGACTCACTTCCTAGATGAGGAAG; TGAAGCTTATCAAGAAGATGGGTGACCACCTGACCAACCTCCACAGGCTGGGTGGCCCGG; AGGCTGGGCTGGGCGAGTATCTCTTCGAAGGCTCACTCTCAAGCACGACTAAGAGCCTTC; TGAGCCCAGCGACTTCTGAAGGGCCCCTTGCAAAGTAATAGGGGCTTCTGCCTAAGCCTC; TCCCTCCAGCCAATAGGCAGCTTTCTTAGCTAATCCTACAAGCCTTTGGACCAAATGGAA; ATAAAGCTTTTTTGATGCTAAAAAAAAAAAAAAAAAAAAAAAAAACTCAACTTTAGATTG; CGGCCGCGGTCATAGCTGGTTCCTGAACAGAACCCGGTGGGCATCCCTGGAACCCTTTCC; TATT;
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_000146 unedited; GGCCTTAGCTTGACCGCGGCCGCTTTCTANGATNCGGTTTTTTTTTTTTTTTTTTTTTTT; TTTTTTGCATCAAAAAGCTTTATTTCCATTTTGGTCCAAGGCTTGTTAGGATAGTTAAAA; AAGCTGCCTATTGGCTGGAGGGAGAGGCTTAAGCAGAAGCCCTATTACTTTGCAAGGGGC; CCTTCAGAAGTCGCTGGGCTCAAAAGGCTCTTAGTCGGGCTTGAGAGTGAGCCTTTCCAA; AAGATACTCGCCCAGCCCAGCCTCCGGGCCACCCAGCCTGAGGAGGTTGGTCAGGGGGTC; ACCCATCTTCTTGATAAACTTCACTTCCTCATCTAGGAAGTGAGTCTCCACGAAGTCACA; GAGATGGGGGTCCGTGCGGCCAAAACCCAGGGCATGAAGATCCAAAAGGGCCTGGGTCAG; CTTTTTCTCCAAGGCCATGGCAGCTTTCATGGCGTCTGGGGTTTTACCCCACTCATCTTC; AACTGGCTTCTTGATGTCCTGGAATAGAGCGCGGCCGCCACGCTGGTTTTGCATCTTCAG; GAGACCCTCGTAGCCCTCGCGCTTCTCCTCGGCCAGTTCGAGGAAGAAGTGGCTCACGCC; TTCCATAGCCACATCATCGCGGCCGAAATAGAACCCCACATAGAGGTAGGTGTAGGAGGC; CTGAAGTACAAATTGACCAAGCTGTTGACGGCTGCCTCCACGTCGGTGGGATAATTCTGA; CGAATCTGGGAGCTCATGGCTGGTTGGCAAGAAAGAGCTAACCACAAAAACGGTGCCTGC; AGGTCCCATAATCAGGAGATGCCCGAGCCTCCTGCCCGAATTCGCGGCCGCCCTTATATG; AGTCGTATTACAAATTGCTGACGCTTCATAAACGAGCTCTGCGTATATAGACCTCCCACC; G;
• Restriction Sites: NotI-NotI
• ACCN: NM_000146
• Insert Size: 470 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_000146.3, NP_000137.2
• RefSeq Size: 889 bp
• RefSeq ORF: 528 bp
• Locus ID: 2512
• UniProt ID: P02792
• Cytogenetics: 19q13.33
• Domains: ferritin
• Protein Families: Druggable Genome
• Summary: This gene encodes the light subunit of the ferritin protein. Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in this light chain ferritin gene are associated with several neurodegenerative diseases and hyperferritinemia-cataract syndrome. This gene has multiple pseudogenes. [provided by RefSeq, Jul 2008]