alpha 1d Adrenergic Receptor (ADRA1D) (NM_000678) Human Untagged Clone

CAT#: SC119760

ADRA1D (untagged)-Human adrenergic, alpha-1D-, receptor (ADRA1D)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: alpha 1d Adrenergic Receptor
• Synonyms: ADRA1; ADRA1A; ADRA1R; ALPHA1; DAR; dJ779E11.2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_000678, RT-PCR generated
  ATGACTTTCCGCGATCTCCTGAGCGTCAGTTTCGAGGGACCCCGCCCGGACAGCAGCGCA
  GGGGGCTCCAGCGCGGGCGGCGGCGGGGGCAGCGCGGGCGGCGCGGCCCCCTCGGAGGGC
  CCGGCGGTGGGCGGCGTGCCAGGGGGCGCGGGCGGCGGCGGCGGCGTGGTGGGCGCAGGC
  AGCGGCGAGGACAACCGGAGCTCCGCGGGGGAGCCGGGGAGCGCGGGCGCGGGCGGCGAC
  GTGAATGGCACGGCGGCCGTCGGGGGACTGGTGGTGAGCGCGCAGGGCGTGGGCGTGGGC
  GTCTTCCTGGCAGCCTTCATCCTTATGGCCGTGGCAGGTAACCTGCTTGTCATCCTCTCA
  GTGGCCTGCAACCGCCACCTGCAGACCGTCACCAACTATTTCATCGTGAACCTGGCCGTG
  GCCGACCTGCTGCTGAGCGCCACCGTACTGCCCTTCTCGGCCACCATGGAGGTTCTGGGC
  TTCTGGGCCTTTGGCCGCGCCTTCTGCGACGTATGGGCCGCCGTGGACGTGCTGTGCTGC
  ACGGCCTCCATCCTCAGCCTCTGCACCATCTCCGTGGACCGGTACGTGGGCGTGCGCCAC
  TCACTCAAGTACCCAGCCATCATGACCGAGCGCAAGGCGGCCGCCATCCTGGCCCTGCTC
  TGGGTCGTAGCCCTGGTGGCGTCCGTAGGGCCCCTGCTGGGCTGGAAGGAGCCCGTGCCC
  CCTGACGAGCGCTTCTGCGGTATCACCGAGGAGGCGGGCTACGCTGTCTTCTCCTCCGTG
  TGCTCCTTCTACCTGCCCATGGCGGTCATCGTGGTCATGTACTGCCGCGTGTACGTGGTC
  GCGCGCAGCACCACGCGCAGCCTCGAGGCGGGCGTCAAGCGCGAGCGAGGCAAGGCCTCC
  GAAGTGGTGCTGCGCATCCACTGTCGCGGCGCGGCCACGGGCGCCGACGGGGCGCACGGC
  ATGCGCAGCGCCAAGGGCCACACCTTCCGCAGCTCGCTCTCCGTGCGCCTGCTCAAGTTC
  TCCCGTGAGAAGAAAGCGGCCAAGACTCTGGCCATCGTCGTGGGTGTCTTCGTGCTCTGC
  TGGTCCCCTTTCTTCTTTGTCCTGCCGCTCGGCTCCTTGTTCCCGCAGCTGAAGCCATCG
  GAGGGCGTCTTCAAGGTCATCTTCTGGCTCGGCTACTTCAACAGCTGCGTGAACCCGCTC
  ATCTACCCCTGTTCCAGCCGCGAGTTCAAGCGCGCCTTCCTCCGTCTCCTGCGCTGCCAG
  TGCCATCGTCGCCGGCGCCGCCGCCCTCTCTGGCGTGTCTACGGCCACCACTGGCGGGCC
  TCCACCAGCGGCCTGCGCCAGGACTGCGCCCCGAGTTCGGGCGACGCGCCCCCCGGAGCG
  CCGCTGGCCCTCACCGCGCTCCCCGACCCCGACCCCGAACCCCCAGGCACGCCCGAGATG
  CAGGCTCCGGTCGCCAGCCGTCGAAAGCCACCCAGCGCCTTCCGCGAGTGGAGGCTGCTG
  GGGCCGTTCCGGAGACCCACGACCCAGCTGCGCGCCAAAGTCTCCAGCCTGTCGCACAAG
  ATCCGCGCCGGGGGCGCGCAGCGCGCAGAGGCAGCGTGCGCCCAGCGCTCAGAGGTGGAG
  GCTGTGTCCCTAGGCGTCCCACACGAGGTGGCCGAGGGCGCCACCTGCCAGGCCTACGAA
  TTGGCCGACTACAGCAACCTACGGGAGACCGATATTTAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_000678 unedited
  NAAACTCGNGATATTTGTTAACACGACTTACTATATGGCGGCACGCCAGTGTGATGGATA
  TCTGCAGAATTCGGCTTGATGACTTTCCGCGATCTCCTGAGCGTCAGTTTCGAGGGACCC
  CGCCCGGACAGCAGCGCAGGGGGCTCCAGCGCGGGCGGCGGCGGGGGCAGCGCGGGCGGC
  GCGGCCCCCTCGGAGGGCCCGGCGGTGGGCGGCGTGCCAGTTTTCTCGGGCGGCGGCGGC
  GGCGTGGTGGGCGCAGGCAGCGGCGAGGACAACCGGAGCTCCGCGGGGGAGCCGGGGAGC
  GCGGGCGCGGGCGGCGACGTGAATGGCACGGCGGCCGTCGGGGGACTGGTGGTGAGCGCG
  CAGGGCGTGGGCGTGGGCGTCTTCCTGGCAGCCTTCATCCTTATGGCCGTGGCAGGTAAC
  CTGCTTGTCATCCTCTCAGTGGCCTGCAACCGCCACCTGCAGACCGTCACCAACTATTTC
  ATCGTGAACCTGGCCGTGGCCGACCTGCTGCTGAGCGCCACCGTACTGCCCTTCTCGGCC
  ACCATGGAGGTTCTGGGCTTCTGGGCCTTTGGCCGCGCCTTCTGCGACGTATGGGCCGCC
  GTGGACGTGCTGTGCTGCACGGCCTCCATCCTCAGCCTCTGCACCATCTCCGTGGACCGG
  TACGTGGGCGTGCGCCACTCACTCAAGTACCCAGCCATCATGACCGAGCGCAAGCGGCCG
  CCATCCTGGCCCTGCTCTGGGTCCGTACCCTGGTGGTGTTCCTAAGGCCCCCTGCTGGGC
  TGGAAAGAACCCGTGCCCCCTGACAAGCCCTTCTGCGGTATCACCGAAGAGGCGGGCTAC
  CCTGGCCTCTCTCCGGGGGCTCCTTTTACCTGCCATTGGGGGGCATTG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_000678 unedited
  ATCGACAAGNCTTGAATCGGTACCGAGCTCGGATCCACTAGTAACGGCCGCCAGTGTGCT
  GGAATTCGGCTTTCTGGGGTCCTTAATATCGGTCTCCCGTAGGTTGCTGTAGTCGGCCAA
  TTCGTAGGCCTGGCAGGTGGCGCCCTCGGCCACCTCGTGTGGGACGCCTAGGGACACAGC
  CTCCACCTCTGAGCGCTGGGCGCACGCTGCCTCTGCGCGCTGCGCGCCCCCGGCGCGGAT
  CTTGTGCGACAGGCTGGAGACTTTGGCGCGCAGCTGGGTCGTGGGTCTCCGGAACGGCCC
  CAGCAGCCTCCACTCGCGGAAGGCGCTGGGTGGCTTTCGACGGCTGGCGACCGGAGCCTG
  CATCTCGGGCGTGCCTGGGGGTTCGGGGTCGGGGTCGGGGAGCGCGGTGAGGGCCAGCGG
  CGCTCCGGGGGGCGCGTCGCCCGAACTCGGGGCGCAGTCCTGTCGCACGCCGCTGGTGGA
  TGCCCGCCAGTGGTGGCGTGTGACACCCCAAAGAGGGCGGCGGCGCCTGGCGACGACGGC
  GCTGGGTTCTGCGCGAGACGGCGGAACGCGCCCTTGACGATGCGGCTGGAGCGAGGGATG
  GCGCGCGGTGTGCACGCCTGCTGTCTCGGTAGCAGGCGCCGGCAGACGGCCCTTGCCGGG
  CGCACTCGTCCCGCGTGCCGTCTTCGCGGGACTGCGGGCGCGCTTATTGTTGTCCGTTGT
  TAGCCGCGCTGTCCGGTCCGTATTGCCGATCAGCGCGCTCGCTCTCGTAGGTGGCGGAGT
  GTCGCCGCCTATATTTTTTACTGGGCAGGGGTGTTTGCGTCGGGCCGATCCACCCCGCCT
  CGTCGCG
  
• Restriction Sites: Please inquire
• ACCN: NM_000678
• Insert Size: 2000 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_000678.2, NP_000669.1
• RefSeq Size: 2130 bp
• RefSeq ORF: 1719 bp
• Locus ID: 146
• UniProt ID: P25100
• Cytogenetics: 20p13
• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Vascular smooth muscle contraction
• Gene Summary: Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1D-adrenergic receptor. Similar to alpha-1B-adrenergic receptor gene, this gene comprises 2 exons and a single intron that interrupts the coding region. [provided by RefSeq, Jul 2008]