Oxytocin Receptor (OXTR) (NM_000916) Human Untagged Clone

CAT#: SC119610

OXTR (untagged)-Human oxytocin receptor (OXTR)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: Oxytocin Receptor
• Synonyms: OT-R; OTR
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC119610 sequence for NM_000916 edited (data generated by NextGen Sequencing)
  ATGGAGGGCGCGCTCGCAGCCAACTGGAGCGCCGAGGCAGCCAACGCCAGCGCCGCGCCG
  CCGGGGGCCGAGGGCAACCGCACCGCCGGACCCCCGCGGCGCAACGAGGCCCTGGCGCGC
  GTGGAGGTGGCGGTGCTGTGTCTCATCCTGCTCCTGGCGCTGAGCGGGAATGCGTGTGTG
  CTGCTGGCGCTGCGCACCACACGCCAGAAGCACTCGCGCCTCTTCTTCTTCATGAAGCAC
  CTAAGCATCGCCGACCTGGTGGTGGCAGTGTTTCAGGTGCTGCCGCAGTTGCTGTGGGAC
  ATCACCTTCCGCTTCTACGGGCCCGACCTGCTGTGCCGCCTGGTCAAGTACTTGCAGGTG
  GTGGGCATGTTCGCCTCCACCTACCTGCTGCTGCTCATGTCCCTGGACCGCTGCCTGGCC
  ATCTGCCAGCCGCTGCGCTCGCTGCGCCGCCGCACCGACCGCCTGGCAGTGCTCGCCACG
  TGGCTCGGCTGCCTGGTGGCCAGCGCGCCGCAGGTGCACATCTTCTCTCTGCGCGAGGTG
  GCTGACGGCGTCTTCGACTGCTGGGCCGTCTTCATCCAGCCCTGGGGACCCAAGGCCTAC
  ATCACATGGATCACGCTAGCTGTCTACATCGTGCCGGTCATCGTGCTCGCTGCCTGCTAC
  GGCCTTATCAGCTTCAAGATCTGGCAGAACTTGCGGCTCAAGACCGCTGCAGCGGCGGCG
  GCCGAGGCGCCAGAGGGCGCGGCGGCTGGCGATGGGGGGCGCGTGGCCCTGGCGCGTGTC
  AGCAGCGTCAAGCTCATCTCCAAGGCCAAGATCCGCACGGTCAAGATGACTTTCATCATC
  GTGCTGGCCTTCATCGTGTGCTGGACGCCTTTCTTCTTCGTGCAGATGTGGAGCGTCTGG
  GATGCCAACGCGCCCAAGGAAGCCTCGGCCTTCATCATCGTCATGCTCCTGGCCAGCCTC
  AACAGCTGCTGCAACCCCTGGATCTACATGCTGTTCACGGGCCACCTCTTCCACGAACTC
  GTGCAGCGCTTCCTGTGCTGCTCCGCCAGCTACCTGAAGGGCAGACGCCTGGGAGAGACG
  AGTGCCAGCAAAAAGAGCAACTCGTCCTCCTTTGTCCTGAGCCATCGCAGCTCCAGCCAG
  AGGAGCTGCTCCCAGCCATCCACGGCGTGA
  
  Clone variation with respect to NM_000916.3
  171 c=>t
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_000916 unedited
  CCATTCGCATCGAGTGGAGATTCTTTCGGGGAGGTGATTTGGTTTTAGATTCCTACTCCC
  GGAGGAACGTTGCTGATTTTGACCCTCCCTTCTCCCCCAGTGGAAGCCGCTGAACATCCC
  GAGGAACTGGCACGCTGGGGGCTCTGGGCTTGTGGCCGGTAGAGGATTCCTGCCTANNTC
  AGTGGCTTATAGGAGGGTGGACTCAGCAGATCCGTCCGTGGAGTCTCCAGGAGTGGAGCC
  CCGGGCGCCCCTACACCCTCCGACACGCCGGATCCGGCCCAGCCGCGCCAAGCCGTAAAG
  GGCTCGAAGGCCGGGGCGCACCGCTGCCGCCAGGGTCATGGAGGGCGCGCTCGCAGCCAA
  CTGGAGCGCCGAGGCAGCCAACGCCAGCGCCGCGCCGCCGGGGGCCGAGGGCAACCGCAC
  CGCCGGACCCCCGCGGCGCAACGAGGCCCTGGCGCGCGTGGAGGTGGCGGTGCTGTGTCT
  CATCCTGCTCCTGGCGCTGAGCGGGAATGCGTGTGTGCTGCTGGCGCTGCGCACCACACG
  CCAGAAGCACTCGCGCCTCTTCTTCTTCATGAAGCACCTAAGCATCGCCGACCTGGTGGT
  GGCAGTGTTTCAAGTGCTGCCGCAGTTGCTGTGGGACATCACCTTCCGCTTCTAAGGCCC
  CGACCTGCTGTGCCGCCTGGTCAAGTACTTGCAGGTGGTGGGCATGTTCGCCTCCACCTA
  CCTGCTGGTGCTCATGTCCCTGGACCGCTGCCTGGCCATCTGCCAACCGCTGCGCTCGTT
  GAGCCGGCGCACCGAACGCCTGGCAGTGCCTCCCCCCGTGGCTTCGCCTGGCCTGGTGGC
  CCACGCGCCCGAGGTGCCCCATTTTTTTTCTGCCCG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_000916 unedited
  GTATGGACCGCGGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTT
  TTCTGTTGAATTTTTTTTGTTTATTTTTATTTTTTAAAGTTCATTGGTTTTTAGTACATT
  CTCAAAATCGTGCACAATCACCACTAATTTCAGAACATTTTCATCACCCGAAAAAAAAAC
  CCCAAACCCTTAGTAGTCATGCCTCATCTCTCACAGCCTCCAGGCCCTGGCAAACGCTAA
  TCTATATTCACTCTATATAGATTCGTCCATTTTAGACATTGCATTTCAATGCAGTCAGAC
  AATATGTGGGCTTTTGCACCTGGCTTCTTTCACTTAGCAAGTTTTCAAGGCTCATCCATG
  TTGTGGCATGTGTGAGTACTTCATTTCTTTTTAGAGTCTAATAATGTTCCATTGCGTGGA
  CAGACCACATTTTATTTCCCATTCATCAGTTGGTAGACATTTGGGTTGTTTCCACTTTTT
  GGCTATTACAAATAATGTTGCTATGAACATTGGTGTACAAGTTTTTGTGTGTATGTACGT
  TTTCATTTCTCTTGGGTAAATACCTAGGAGTGGCATTCCTGGGTCATATGGTCACTCTAC
  GTTTAACTTTTTGAGGTACTGCCAAACTGTTTTTCAAAGCAGGTGCACCATTTACATTCC
  CACCAACAATTTAAATTTCTACCAGTTTCTCTACATCCTCACCGACACTCGTTCTTGTCC
  ATCTTTTTATTGTAGCCATCCTAGTGATTGTAAACTGGAATCTCATTGTGATTTTGACTT
  GCATTTCCCTAATGAATATAATGTTGAGTATTTTTTCATGTGGCTAGTACCATTTGCATA
  TCTTCTTTGGAGAAATGCTATTCAAACCGTTAGCCCATTTTTAAATTGNATTATTTTTCT
  CCTTATTGGGGGGTTAAAGAATTATTTTATATTTCCGAAACAAGCCCTTATATAATATGA
  CTCCAAAATTTTTCCCTTTGCG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_000916
• Insert Size: 4500 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_000916.3, NP_000907.2
• RefSeq Size: 4361 bp
• RefSeq ORF: 1170 bp
• Locus ID: 5021
• UniProt ID: P30559
• Cytogenetics: 3p25.3
• Domains: 7tm_1
• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Calcium signaling pathway, Neuroactive ligand-receptor interaction
• Gene Summary: The protein encoded by this gene belongs to the G-protein coupled receptor family and acts as a receptor for oxytocin. Its activity is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. The oxytocin-oxytocin receptor system plays an important role in the uterus during parturition. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) represents the longest transcript. Variants 1-5 all encode the same protein.