CTBP1 (NM_001328) Human Untagged Clone

CAT#: SC119309

CTBP1 (untagged)-Human C-terminal binding protein 1 (CTBP1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CTBP1
• Synonyms: BARS; HADDTS
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC119309 sequence for NM_001328 edited (data generated by NextGen Sequencing)
  ATGGGCAGCTCGCACTTGCTCAACAAGGGCCTGCCGCTTGGCGTCCGACCTCCGATCATG
  AACGGGCCCCTGCACCCGCGGCCCCTGGTGGCATTGCTGGATGGCCGGGACTGCACAGTG
  GAGATGCCCATCCTGAAGGACGTGGCCACTGTGGCCTTCTGCGACGCGCAGTCCACGCAG
  GAGATCCATGAGAAGGTCCTGAACGAGGCTGTGGGGGCCCTGATGTACCACACCATCACT
  CTCACCAGGGAGGACCTGGAGAAGTTCAAAGCCCTCCGCATCATCGTCCGGATTGGCAGT
  GGTTTTGACAACATCGACATCAAGTCGGCCGGGGATTTAGGCATTGCCGTCTGCAACGTG
  CCCGCGGCGTCTGTGGAGGAGACGGCCGACTCGACGCTGTGCCACATCCTGAACCTGTAC
  CGGCGGGCCACCTGGCTGCACCAGGCGCTGCGGGAGGGCACACGAGTCCAGAGCGTCGAG
  CAGATCCGCGAGGTGGCGTCCGGCGCTGCCAGGATCCGCGGGGAGACCTTGGGCATCATC
  GGACTTGGTCGCGTGGGGCAGGCAGTGGCGCTGCGGGCCAAGGCCTTCGGCTTCAACGTG
  CTCTTCTACGACCCTTACTTGTCGGATGGCGTGGAGCGGGCGCTGGGGCTGCAGCGTGTC
  AGCACCCTGCAGGACCTGCTCTTCCACAGCGACTGCGTGACCCTGCACTGCGGCCTCAAC
  GAGCACAACCACCACCTCATCAACGACTTCACCGTCAAGCAGATGAGACAAGGGGCCTTC
  CTGGTGAACACAGCCCGGGGTGGCCTGGTGGATGAGAAGGCGCTGGCCCAGGCCCTGAAG
  GAGGGCCGGATCCGCGGCGCGGCCCTGGATGTGCACGAGTCGGAACCCTTCAGCTTTAGC
  CAGGGCCCTCTGAAGGATGCACCCAACCTCATCTGCACCCCCCATGCTGCATGGTACAGC
  GAGCAGGCATCCATCGAGATGCGAGAGGAGGCGGCACGGGAGATCCGCAGAGCCATCACA
  GGCCGGATCCCAGACAGCCTGAAGAACTGTGTCAACAAGGACCATCTGACAGCCGCCACC
  CACTGGGCCAGCATGGACCCCGCCGTCGTGCACCCTGAGCTCAATGGGGCTGCCTATAGG
  TACCCTCCGGGCGTGGTGGGCGTGGCCCCCACTGGCATCCCAGCTGCTGTGGAAGGTATC
  GTCCCCAGCGCCATGTCCCTGTCCCACGGCCTGCCCCCTGTGGCCCACCCGCCCCACGCC
  CCTTCTCCTGGCCAAACCGTCAAGCCCGAGGCGGATAGAGACCACGCCAGTGACCAGTTG
  TAG
  
  Clone variation with respect to NM_001328.2
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001328 unedited
  GTTCGAATTTGTATACGACTCCTATAGGGCGGCCGCGAATTCGCACCAGGCGGCGGAGAC
  TCGGCACGGCGGCGGCCAGGCGCAGGCGGGCGGGCGGAGCAGCGGACGGCGCCGAGGCCG
  CCCCACGCGCCGGGCTCGCGGCGGCGCAGCGCGCCGGAGTGGTCGGGGCCCGCGGCCGCT
  CGCGCCTCTCGATGGGCAGCTCGCACTTGCTCAACAAGGGCCTGCCGCTTGGCGTCCGAC
  CTCCGATCATGAACGGGCCCCTGCACCCGCGGCCCCTGGTGGCATTGCTGGATGGCCGGG
  ACTGCACAGTGGAGATGCCCATCCTGAAGGACGTGGCCACTGTGGCCTTCTGCGACGCGC
  AGTCCACGCAGGAGATCCATGAGAAGGTCCTGAACGAGGCTGTGGGGGCCCTGATGTACC
  ACACCATCACTCTCACCAGGGAGGACCTGGAGAAGTTCAAAGCCCTCCGCATCATCGTCC
  GGATTGGCAGTGGTTTTGACAACATCGACATCAAGTCGGCCGGNGATTTAGGCATTGCCG
  TCTGCAACGTGCCCGCGGCGTCTGTGGAGGAGACGGNCGACTCGACGCTGTGCCACATCC
  TNGACCTGTACCGGCGGGCCACCTGGCTGCACCAGGCGCTGNCGGAGGGCACACGAGTCC
  AGAGCGTCGAGCAGATCCGCGAGGTGGCGTCCGGCGCTGCCAGGATCCGCGGNGAGACCT
  TGGGCATCATCGNACTTGNTCGCGTGGGGCAAGCAATGGCGCTGCGGNCCAAAGGCTTTC
  GCTTAACGTGCTCTTCTACGACCTTNACTTTGTCGAATGCGTGGACCGGCCCCTGGGGCC
  TGCACGTGTCAACACCCTTGCAGACCTGGTTTTCCACAGNGACTGGNTGACCCTGCACTG
  NNGGCTCTANGGAGCCAACCACCACCTCATTNACGACTTTACCGGNAAGCAATGG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_001328 unedited
  AAAAAACCTTGGGGGNCTATTTTACTCTTTTAAAATTGATACAAAGGTTACAGTCACAAA
  CATGATTTTAACCAAAATATTGCTAGCCTACCACATCAGCAGGACGGCACTGGTGCAGGC
  GGGGACGCTGCCACCCTCCACGTCCCCAGGACAGACGTCGATGGGCAGCGGGCACGCTGG
  GCACCGCCCAAGCTTTTCCTTTTGGAGCTGCTTCGTGATGCCGTCTTCATTTGGAACAAG
  GGGGGGTTCATGCCAAAATTAGGAAAAACAGCCTTTGTTTTGTTTTTCTAAATTATTCTA
  AAAATAAGACAAGCAGGTAGAAAAAACAATGCACTGTGTGGCATAAAAAGAAAAACGGGA
  AGGATTCATTGTCCTGAGAAGTTTGCCAACTGCCTCATTCTGGGGCACGTTCCAACATAC
  AAAAAAAAAAAAACCAAAAAAAAAAACCTCAAATTGACTTCCAAATGCTCCTTCAGGTTT
  TCTTTTTGTTGACAGCTAAGCAAACAGATCCTTTGTAATGTTCTAAAAACTGTACACAGA
  CAAGAACGTTCATGGGAGAATAACTACTGACTTCTTCTGCTTAACGAGGAACGCGAAGGA
  CACAGGGCAGAGCGCCCACAGGACGGACGACGACAAGCGACACGAGGCCCAGCGCTGCCC
  CCTCCCGCCTCCTGACAGCCCGGACCAGTCTCTGCAGTGCCAGGGCCACCACACAGATGC
  CTCCTCCACACACTCTGGTCCGAGGGTTTCCGGGCCCTCTGCCCAGGCGCCGAGGCTGGA
  GAGCTCCTCCCGGGCTACAACTGGTCACTGGCGTGGTCTCTATCCGCCTCGGGCTTGACG
  GTTTGGCCAGGATAAGGGGCGTGGGGCGGGTGGGCCACAGGGGGCAG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_001328
• Insert Size: 2500 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001328.2, NP_001319.1
• RefSeq Size: 2288 bp
• RefSeq ORF: 1323 bp
• Locus ID: 1487
• UniProt ID: Q13363
• Cytogenetics: 4p16.3
• Domains: 2-Hacid_DH, 2-Hacid_DH_C
• Protein Pathways: Chronic myeloid leukemia, Notch signaling pathway, Pathways in cancer, Wnt signaling pathway
• Gene Summary: This gene encodes a protein that binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. This protein and the product of a second closely related gene, CTBP2, can dimerize. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development. Alternative splicing of transcripts from this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) encodes the longer isoform (1).