CXCR3 (NM_001504) Human Untagged Clone

CAT#: SC119210

CXCR3 (untagged)-Human chemokine (C-X-C motif) receptor 3 (CXCR3), transcript variant A

USD 196.00


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Size
    • 10 ug

Product images

Specifications

Product Data
Product Name CXCR3 (NM_001504) Human Untagged Clone
Symbol CXCR3
Synonyms CD182; CD183; CKR-L2; CMKAR3; GPR9; IP10-R; Mig-R; MigR
Vector pCMV6-XL4
Sequence Data
Fully Sequenced ORF
>OriGene sequence for NM_001504 edited
GAATTCGGCACCAGCAGCACACCACCCAGCAGCCAGAGCACCAGCCCAGCCATGGTCCTT
GAGGTGAGTGACCACCAAGTGCTAAATGACGCCGAGGTTGCCGCCCTCCTGGAGAACTTC
AGCTCTTCCTATGACTATGGAGAAAACGAGAGTGACTCGTGCTGTACCTCCCCGCCCTGC
CCACAGGACTTCAGCCTGAACTTCGACCGGGCCTTCCTGCCAGCCCTCTACAGCCTCCTC
TTTCTGCTGGGGCTGCTGGGCAACGGCGCGGTGGCAGCCGTGCTGCTGAGCCGGCGGACA
GCCCTGAGCAGCACCGACACCTTCCTGCTCCACCTAGCTGTAGCAGACACGCTGCTGGTG
CTGACACTGCCGCTCTGGGCAGTGGACGCTGCCGTCCAGTGGGTCTTTGGCTCTGGCCTC
TGCAAAGTGGCAGGTGCCCTCTTCAACATCAACTTCTACGCAGGAGCCCTCCTGCTGGCC
TGCATCAGCTTTGACCGCTACCTGAACATAGTTCATGCCACCCAGCTCTACCGCCGGGGG
CCCCCGGCCCGCGTGACCCTCACCTGCCTGGCTGTCTGGGGGCTCTGCCTGCTTTTCGCC
CTCCCAGACTTCATCTTCCTGTCGGCCCACCACGACGAGCGCCTCAACGCCACCCACTGC
CAATACAACTTCCCACAGGTGGGCCGCACGGCTCTGCGGGTGCTGCAGCTGGTGGCTGGC
TTTCTGCTGCCCCTGCTGGTCATGGCCTACTGCTATGCCCACATCCTGGCCGTGCTGCTG
GTTTCCAGGGGCCAGCGGCGCCTGCGGGCCATGCGGCTGGTGGTGGTGGTCGTGGTGGCC
TTTGCCCTCTGCTGGACCCCCTATCACCTGGTGGTGCTGGTGGACATCCTCATGGACCTG
GGCGCTTTGGCCCGCAACTGTGGCCGAGAAAGCAGGGTAGACGTGGCCAAGTCGGTCACC
TCAGGCCTGGGCTACATGCACTGCTGCCTCAACCCGCTGCTCTATGCCTTTGTAGGGGTC
AAGTTCCGGGAGCGGATGTGGATGCTGCTCTTGCGCCTGGGCTGCCCCAACCAGAGAGGG
CTCCAGAGGCAGCCATCGTCTTCCCGCCGGGATTCATCCTGGTCTGAGACCTCAGAGGCC
TCCTACTCGGGCTTGTGAGGCCGGAATCCGGGCTCCCCTTTCGCCCACAGTCTGACTTCC
CCGCATTCCAGGCTCCTCCCTCCCTCTGCCGGCTCTGGCTCTCCCCAATATCCTCGCTCC
CGGGACTCACTGGCAGCCCCAGCACCACCAGGTCTCCCGGGAAGCCACCCTCCCAGCTCT
GAGGACTGCACCATTGCTGCTCCTTAGCTGCCAAGCCCCATCCTGCCGCCCGAGGTGGCT
GCCTGGAGCCCCACTGCCCTTCTCATTTGGAAACTAAAACTTCATCTTCCCCAAGTGCGG
GGAGTACAAGGCATGGCGTAGAGGGTGCTGCCCCATGAAGCCACAGCCCAGGCCTCCAGC
TCAGCAGTGACTGTGGCCATGGTCCCCAAGACCTCTATATTTGCTCTTTTATTTTTATGT
CTAAAATCCTGCTTAAAACTTTTCAATAAACAAGATCGTCAGGAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAACTCGAC
5' Read Nucleotide Sequence
>OriGene 5' read for NM_001504 unedited
AGGGGCAACCACNNTCCCCCCCCCCCCGTTCAAATTTGTATACGACTCACTATAGGCGGC
CGCGAATTCGCACCAGCAGCACACCACCCAGCAGCCAGAGCACCAGCCCAGCCATGGTCC
TTGAGGTGAGTGACCACCAAGTGCTAAATGACGCCGAGGTTGCCGCCCTCCTGGAGAACT
TCAGCTCTTCCTATGACTATGGAGAAAACGAGAGTGACTCGTGCTGTACCTCCCCGCCCT
GCCCACAGGACTTCAGCCTGAACTTCGACCGGGCCTTCCTGCCAGCCCTCTACAGCCTCC
TCTTTCTGCTGGGGCTGCTGGGCAACGGCGCGGTGGCAGCCGTGCTGCTGAGCCGGCGGA
CAGCCCTGAGCAGCACCGACACCTTCCTGCTCCACCTAGCTGTAGCAGACACGCTGCTGG
TGCTGACACTGCCGCTCTGGGCAGTGGACGCTGCCGTCCAGTGGGTCTTTGGCTCTGGCC
TCTGCAAAGTGGCAGGTGCCCTCTTCAACATCAACTTCTACGCAGGAGCCCTCCTGCTGG
CCTGCATCAGCTNTGACCGCTACCTGAACATAGTTCATGCCACCCAGCTCTACCGCCGGN
GGCCCCCGGCCCGCGTGACCCTCACCTGCCTGGCTGTCTGGNGGCTCTGCCTGCTTTTCG
CCCTCCCAGACTTCATCTTCCTGTNCGCCCACCACGACGAGCGCCTCAACGCCACCCACT
GNCAATACAACTTNCCACAGGTGGGCCGCACGGCTCTGCGGNTGCTGCAACTGGTGCCTT
GGCTTTCTGCTGCCCCTGCTGGTCATGGCCTACTGCTATGCCCACATCCTGGCCGTGCTG
CNTGGNTTTCAGGGGCCCAGCGCGCCCTGCGGGCATGCGGCTTGTNGTGGNGGGCCCTGG
TGGCCTTTGCCTTCTGCTGGNACCCCTTCCACCTGTGGNGCCTGGGGACACTNCTCATGG
ACCTGGNCGCTTTTGGCCGGCACCGTGGGCG
3' Read Nucleotide Sequence
>OriGene 3' read for NM_001504 unedited
TACNATGATCGATTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TCTCCGGACAATCTTGTTTATTGAAAAAGTTTTAACCAGGATTTTAAACCTAAAAATAAA
AAACCAAATTTAGAGGTCTTGGGGACCATGGCCACAGTCACTGCTGACCTGGAGGCCTGG
GCTGGGGCTTCATGGGGAAACACCCTTTACCCCATGCCTTGTACTCCCCGCACTTGGGAA
AAATAAATTTTTATTTTCCAAATGAAAAGGGCAGGGGGGCTCCAGGCAGCCACCTCGGGC
GGCAGGATGGGGCTTGGCACCTAAGGACCACCAATGGGGCAGCCCTCAAAGCTGGGAGGG
GGGCTTCCCGGAAAACCTGGGGGGGCTGGGGCTGCCAGTGATTCCCGGGAGCGAGGATTT
TGGGGAAAGCCAAACCCGGCCAAAGGGAGGGAGGACCCTGGAATGCGGGGAATTCAAACT
GGGGGCAAAAGGGGACCCCGGATTCCGGCCTCACAACCCCGATTAGGAGGCCTCTGAGGT
CTCAAACCAGGATGAATCCCGGCGGGAAAACAATGGCTGCCTCTGGACCCCTCTTTGGTT
GGGGCATCCCAGGCGCAAAATCATATCCAAATTCCGCTCCCGGAACTTGACCCCTACAAA
GGCATAAACCACCGGGTTGAGGCCCCATTGCTTGTACCCCCAAGCCCGGAGGGGACCCCA
TTTGGCCAGTTCTACCCTGGGTTTCTTGGCCAAAATTGGGGGGCGAAAACCCCCCAGGCC
CATGGAGATGTTCCCCCCCCCCCCCCCGG
Restriction Sites NotI-NotI     
Tag Tag Free
ACCN NM_001504
ORF Size 1107 bp
Insert Size 1750
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reference Data
RefSeq NM_001504.1, NP_001495
RefSeq Size 1670
Locus ID 2833
Cytogenetics Xq13.1
Domains 7tm_1
Protein Families GPCR, Transmembrane, Druggable Genome
Protein Pathways Cytokine-cytokine receptor interaction, Chemokine signaling pathway
Gene Summary This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716). [provided by RefSeq, Jun 2011].
Transcript Variant: This variant (1) represents the predominant transcript, and encodes isoform 1 (also known as CXCR3-A). This isoform functions as a receptor for chemokines CXCL9/Mig, CXCL10/IP-10, and CXCL11/I-TAC (PMID:12782716).
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.