Retinoid X Receptor alpha (RXRA) (NM_002957) Human Untagged Clone

SKU SC118299

RXRA (untagged)-Human retinoid X receptor, alpha (RXRA)

Product Data

• Type: Human Untagged Clone
• Target Symbol: Retinoid X Receptor alpha
• Synonyms: NR2B1
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_002957 edited; ATGGACACCAAACATTTCCTGCCGCTCGATTTCTCCACCCAGGTGAACTCCTCCCTCACC; TCCCCGACGGGGCGAGGCTCCATGGCTGCCCCCTCGCTGCACCCGTCCCTGGGGCCTGGC; ATCGGCTCCCCGGGACAGCTGCATTCTCCCATCAGCACCCTGAGCTCCCCCATCAACGGC; ATGGGCCCGCCTTTCTCGGTCATCAGCTCCCCCATGGGCCCCCACTCCATGTCGGTGCCC; ACCACACCCACCCTGGGCTTCAGCACTGGCAGCCCCCAGCTCAGCTCACCTATGAACCCC; GTCAGCAGCAGCGAGGACATCAAGCCCCCCCTGGGCCTCAATGGCGTCCTCAAGGTCCCC; GCCCACCCCTCAGGAAACATGGCTTCCTTCACCAAGCACATCTGCGCCATCTGCGGGGAC; CGCTCCTCAGGCAAGCACTATGGAGTGTACAGCTGCGAGGGGTGCAAGGGCTTCTTCAAG; CGGACGGTGCGCAAGGACCTGACCTACACCTGCCGCGACAACAAGGACTGCCTGATTGAC; AAGCGGCAGCGGAACCGGTGCCAGTACTGCCGCTACCAGAAGTGCCTGGCCATGGGCATG; AAGCGGGAAGCCGTGCAGGAGGAGCGGCAGCGTGGCAAGGACCGGAACGAGAATGAGGTG; GAGTCGACCAGCAGCGCCAACGAGGACATGCCGGTGGAGAGGATCCTGGAGGCTGAGCTG; GCCGTGGAGCCCAAGACCGAGACCTACGTGGAGGCAAACATGGGGCTGAACCCCAGCTCG; CCGAACGACCCTGTCACCAACATTTGCCAAGCAGCCGACAAACAGCTTTTCACCCTGGTG; GAGTGGGCCAAGCGGATCCCACACTTCTCAGAGCTGCCCCTGGACGACCAGGTCATCCTG; CTGCGGGCAGGCTGGAATGAGCTGCTCATCGCCTCCTTCTCCCACCGCTCCATCGCCGTG; AAGGACGGGATCCTCCTGGCCACCGGGCTGCACGTCCACCGGAACAGCGCCCACAGCGCA; GGGGTGGGCGCCATCTTTGACAGGGTGCTGACGGAGCTTGTGTCCAAGATGCGGGACATG; CAGATGGACAAGACGGAGCTGGGCTGCCTGCGCGCCATCGTCCTCTTTAACCCTGACTCC; AAGGGGCTCTCGAACCCGGCCGAGGTGGAGGCGCTGAGGGAGAAGGTCTATGCGTCCTTG; GAGGCCTACTGCAAGCACAAGTACCCAGAGCAGCCGGGAAGGTTCGCTAAGCTCTTGCTC; CGCCTGCCGGCTCTGCGCTCCATCGGGCTCAAATGCCTGGAACATCTCTTCTTCTTCAAG; CTCATCGGGGACACACCCATTGACACCTTCCTTATGGAGATGCTGGAGGCGCCGCACCAA; ATGACTTAG;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_002957 unedited; ACAAAACTCTCTTCCCCGCCCGTTGNCNCACTAGGGCGGTAGCGTGTACGGTGGGAAGGT; CTATATAAGCAGAGCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGG; GCGGCCGCGAATTCGGCACGAGCCGCCGCCGCCACCGCAGCCGCCGGCTCCCCGCCGCCC; GGGCCCGGGCCGGCCGCGCCGGGGGCCGCCGCGCCCGCCGCCCGCTGCCTGCGCCGCCGG; CCGGGCATGAGTTAGTCGCAGACATGGACACCAAACATTTCCTGCCGCTCGATTTCTCCA; CCCAGGTGAACTCCTCCCTCACCTCCCCGACGGGGCGAGGCTCCATGGCTGCCCCCTCGC; TGCACCCGTCCCTGGGGCCTGGCATCGGCTCCCCGGGACAGCTGCATTCTCCCATCAGCA; CCCTGAGCTCCCCCATCAACGGCATGGGCCCGCCTTTCTCGGTCATCAGCTCCCCCATGG; GCCCCCACTCCATGTCGGTGCCCACCACACCCACCCTGGGCTTCAGCACTGGCAGCCCCC; AGCTCAGCTCACCTATGAACCCCGTCAGCAGCAGCGAGGACATCAAGCCCCCCCTGGGCC; TCAATGGCGTCCTCAAGGTCCCCGCCCACCCCTCAAGAAACATGGCTTCCTTCACCAAGC; ACATCTGCGCCATCTGCGGGGACCGCTCCTCAGCAAGCACTATGGAGTGTACAGCTGCGA; GGGGTGCAAGGGCTTCTTCAAGCGGACGGTGCGCAAGGACCTGACCTACACCTGCCGCGA; CAACAAGGACTGCCCTGATTGACAGCGGCAGCGGGAACCGGTGCCAGTACTGCCGCTACC; ANAAGTGCCTGGCCATGGGCATGAACCGGGAAGCCTTGCAAGAGGACCGCACCTT;
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_002957 unedited; TGGGCCGAATCACTGTGNACCGCGCCCCTCTTNNCTANGATCGGTTTNCTTTTTTTTTTT; TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTAAAAGGGGGGGGACA; ACCCATTTTTTAAGCAAAACAGTGACAGGCTGGGCCCCAAAGTCCAAACAGGCCAGGCAA; AAAAGGGCAGGGACAGGGCTCAGGCTGAAAAAAAATTTGGGGTCCACGCAGGGGGGCCAA; AACGGGGGGGCACAAAGGATGGGCCCCCAGGCCTAAATCATTTGGGGGGGCGCCTCCAGC; ATTTCCATAAGGAAGGGGTCAATGGGGGGGTCCCCGATGAGCTTGAAAAAAAAAAAATGT; TCCAGGCAATTGACCCCCATGGAGCCCAAAACCACCAGGCGGAACAAGAACTTAACGAAC; CTTCCCGGGTGCTCTGGGTACTTGGGCTTGCAAAAGGCCCCCAAGGACCCATAAACCTTT; TCCCTCTAGGGCCTCCACCTTGGCCGGGTTCGAAAGCCCCTTGGAGTCAGGGTTAAAAAG; GACAAAGGCGCCCAGGCAACCCAACTCCGTTTTGGCCATTTGCATGTCCCGCATTTTGGA; CACAAGCTCCGTCAGCCACCTGTCAAAAATGGCGCCCACCCCTGCCCTATATGGCGCTTT; TCCGGTGGACGTGCACCCCGGTGGCCAAGAAGATCCCCTCCTTCACGGCGAATGGAACGG; TGGGAAAAAAGAAGCCAAAAAACACACTTATTCCAACCTGCCCCCCAAAAAGAATGACCC; TGGTCTTCCAGGGGGCAACTCTTGAAAAATGTGGGGATCCGCCTTGGCCCCCCTCCACCA; CGGGTGAAAAACCTGTTTTTCCGGCTGCTTGTGCAATGTTTGGGGAAAGGGTCCTCTCCG; CGAACCTGGGGGTC;
• Restriction Sites: NotI-NotI
• ACCN: NM_002957
• Insert Size: 1389 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_002957.3, NP_002948.1
• RefSeq Size: 5449 bp
• RefSeq ORF: 1389 bp
• Locus ID: 6256
• UniProt ID: P19793
• Cytogenetics: 9q34.2
• Domains: HOLI, zf-C4
• Protein Families: Druggable Genome, Nuclear Hormone Receptor, Transcription Factors
• Protein Pathways: Adipocytokine signaling pathway, Non-small cell lung cancer, Pathways in cancer, PPAR signaling pathway, Small cell lung cancer, Thyroid cancer
• Summary: Retinoid X receptors (RXRs) and retinoic acid receptors (RARs) are nuclear receptors that mediate the biological effects of retinoids by their involvement in retinoic acid-mediated gene activation. These receptors function as transcription factors by binding as homodimers or heterodimers to specific sequences in the promoters of target genes. The protein encoded by this gene is a member of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2014]; Transcript Variant: This variant (1) encodes the longest isoform (a).