CXCL5 (NM_002994) Human Untagged Clone

CAT#: SC118269

CXCL5 (untagged)-Human chemokine (C-X-C motif) ligand 5 (CXCL5)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CXCL5
• Synonyms: ENA-78; SCYB5
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_002994 edited
  ATGAGCCTCCTGTCCAGCCGCGCGGCCCGTGTCCCCGGTCCTTCGAGCTCCTTGTGCGCG
  CTGTTGGTGCTGCTGCTGCTGCTGACGCAGCCAGGGCCCATCGCCAGCGCTGGTCCTGCC
  GCTGCTGTGTTGAGAGAGCTGCGTTGCGTTTGTTTACAGACCACGCAGGGAGTTCATCCC
  AAAATGATCAGTAATCTGCAAGTGTTCGCCATAGGCCCACAGTGCTCCAAGGTGGAAGTG
  GTAGCCTCCCTGAAGAACGGGAAGGAAATTTGTCTTGATCCAGAAGCCCCTTTTCTAAAG
  AAAGTCATCCAGAAAATTTTGGACGGTGGAAACAAGGAAAACTGA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_002994 unedited
  NNGGTCAGAATTTGTATACGACTCATATAGGCGGCNCGCGAATCGGCACGAGGCCATGAG
  TTCAGGGAATTTCCCCAGCATCCCAAAGCTTGAGTTTCCTGTCAGTGGGGAGAGATGAGT
  GTAGATAAAAGGAGTGCAGAAGGCACGAGGAAGCCACAGTGCTCCGGATCCTCCAATCTT
  CGCTCCTCCAATCTCCGCTCCTCCACCCAGTTCAGGAACCCGCGACCGCTCGCAGCGCTC
  TCTTGACCACTATGAGCCTCCTGTCCAGCCGCGCGGCCCGTGTCCCCGGTCCTTCGAGCT
  CCTTGTGCGCGCTGTTGGTGCTGCTGCTGCTGCTGACGCAGCCAGGGCCCATCGCCAGCG
  CTGGTCCTGCCGCTGCTGTGTTGAGAGAGCTGCGTTGCGTTTGTTTACAGACCACGCAGG
  GAGTTCATCCCAAAATGATCAGTAATCTGCAAGTGTTCGCCATAGGCCCACAGTGCTCCA
  AGGTGGAAGTGGTAGCCTCCCTGAAGAACGGGAAGGAAATTTGTCTTGATCCAGAAGCCC
  CTTTTCTAAAGAAAGTCATCCAGAAAATTTTGGACGGTGGAAACAAGGAAAACTGATTAA
  GAGAAATGAGCACGCATGGAAAAGTTTCCCAGTCTTCAGCAGAGAAGTTTTCTGGAGGTC
  TCTGAACCCAGGGAAGACAAGAGGAAAGATTTTGNTGGTGGTTGGTTATTTGTTTTTCCA
  GNAGTTAGCTTTCTTCCTGGATTCCTCACTNTGAAGAGTGTGAGGAAAACCCTATGTTGC
  CGCTTAAGCTNTCAGCTCAGCTAATGAAGTGGTTAGCATAGNACCTTTGCTATNTGCCGG
  NTANTTATCTGCATCGCAATGGAAAGTTTTGGCAATGACTATAGTGTGAGCCAGAATACC
  TG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_002994 unedited
  ACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGAAGTTTAGAAATCTTT
  TAATGTTTATTCAAAGGACAAAATAAAGACTATGAACCAATGAGACACATAGTAAAAAAG
  TACAATTTTAATATAGTGAATGTAATATATATGTAATTACTCATAACAAAATGGTCAAAA
  CCTTTAAAAGATACACAATAGGCATCTAAAAAGCTCAGCAATGCTAAATATATAATATAT
  ATTATATATAAATATATAATATATAAATACATACGTTTTTACCAAGAAATGTTTTATTTT
  TCTTGCAGTAGCTTTGTTAATTGCACAAAATTATGTTTTGTTTTTGCCATTTAAATATTA
  TCACAGAATCCTATTCTGAAAGACAAATGTTCATTAAAAACAAAGCAAAAATAGAAATTC
  ACAACCATTAATTACCTAGGTTTGTCATTTAAAGGTTTAAAGAAAAAAAGGGAGGAGCTT
  TCCTACAAGCCTTTTCACAAGTGTCACATTTTCTCTTTAAAAGGGAAGGATTTCCAAACA
  AAGGTGAAATAGCTTAAACAGAAATATTTGTAAAAATAAACTTTACAGCATTATCAAGGA
  TATTAAGACAACACTGACTAACCGGTTTCATTACCGCATCTTTCCCCCACCCCCAACCCC
  AGTGTGTCCCACCAGGACTAGAACAGGCTTTACATTCAGACAGAAATGCTTCAAAATCCA
  GTGAAATGAACTGTGCTAAAAACCCGACGGCATTTTCCCTGCCCTCCCGCTGGCGNTCGT
  TTTCTGCAATCCTTTTACCCAGGTTCTACTTTGTGAAAGGGCCAAAACTGTGAGTGGGGA
  GGGAACTTGCCCAACGTGTCCCCTTTATATATATAATATATCTACCATANTGCGGCCCTT
  CTCTAATTATGATTTGGAAATTTTACCCTCCGAAGTATAAAAATGACTCCCT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_002994
• Insert Size: 2790 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_002994.3, NP_002985.1
• RefSeq Size: 2475 bp
• RefSeq ORF: 345 bp
• Locus ID: 6374
• UniProt ID: P42830
• Cytogenetics: 4q13.3
• Domains: IL8
• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Chemokine signaling pathway, Cytokine-cytokine receptor interaction
• Gene Summary: This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils, to promote angiogenesis and to remodel connective tissues. This protein is thought to play a role in cancer cell proliferation, migration, and invasion. [provided by RefSeq, May 2013]