S6K1(RPS6KB1) (NM_003161) Human Untagged Clone

CAT#: SC118140

RPS6KB1 (untagged)-ORIGENE UNIQUE VARIANT 1 of Human ribosomal protein S6 kinase, 70kDa, polypeptide 1 (RPS6KB1)

USD 835


Availability*
In Stock

Size
    • 10 ug

Product images

Specifications

Product Data
Product Name S6K1(RPS6KB1) (NM_003161) Human Untagged Clone
Symbol RPS6KB1
Synonyms p70 S6KA; p70(S6K)-alpha; p70-alpha; p70-S6K; PS6K; S6K; S6K-beta-1; S6K1; STK14A
Vector pCMV6-XL5
Sequence Data
Fully Sequenced ORF
>OriGene ORF sequence for NM_003161 edited
ATGAGGCGACGAAGGAGGCGGGACGGCTTTTACCCAGCCCCGGACTTCCGAGACAGGGAA
GCTGAGGACATGGCAGGAGTGTTTGACATAGACCTGGACCAGCCAGAGGACGCGGGCTCT
GAGGATGAGCTGGAGGAGGGGGGTCAGTTAAATGAAAGCATGGACCATGGGGGAGTTGGA
CCATATGAACTTGGCATGGAACATTGTGAGAAATTTGAAATCTCAGAAACTAGTGTGAAC
AGAGGGCCAGAAAAAATCAGACCAGAATGTTTTGAGCTACTTCGGGTACTTGGTAAAGGG
GGCTATGGAAAGGTTTTTCAAGTACGAAAAGTAACAGGAGCAAATACTGGGAAAATATTT
GCCATGAAGGTGCTTAAAAAGGCAATGATAGTAAGAAATGCTAAAGATACAGCTCATACA
AAAGCAGAACGGAATATTCTGGAGGAAGTAAAGCATCCCTTCATCGTGGATTTAATTTAT
GCCTTTCAGACTGGTGGAAAACTCTACCTCATCCTTGAGTATCTCAGTGGAGGAGAACTA
TTTATGCAGTTAGAAAGAGAGGGAATATTTATGGAAGACACTGCCTGGCTTGAGTGGAAC
GCTCTTCACACCAGTTGTTCCTAACAGAACCATTCTCATTGCGGCTTTCTTTCCTTGAAT
TGCTTTTACTTGGCAGAAATCTCCATGGCTTTGGGGCATTTACATCAAAAGGGGATCATC
TACAGAGACCTGAAGCCGGAGAATATCATGCTTAATCACCAAGGTCATGTGAAACTAACA
GACTTTGGACTATGCAAAGAATCTATTCATGATGGAACAGTCACACACACATTTTGTGGA
ACAATAGAATACATGGCCCCTGAAATCTTGATGAGAAGTGGCCACAATCGTGCTGTGGAT
TGGTGGAGTTTGGGAGCATTAATGTATGACATGCTGACTGGAGCACCCCCATTCACTGGG
GAGAATAGAAAGAAAACAATTGACAAAATCCTCAAATGTAAACTCAATTTGCCTCCCTAC
CTCACACAAGAAGCCAGAGATCTGCTTAAAAAGCTGCTGAAAAGAAATGCTGCTTCTCGT
CTGGGAGCTGGTCCTGGGGACGCTGGAGAAGTTCAAGCTCATCCATTCTTTAGACACATT
AACTGGGAAGAACTTCTGGCTCGAAAGGTGGAGCCCCCCTTTAAACCTCTGTTGCAATCT
GAAGAGGATGTAAGTCAGTTTGATTCCAAGTTTACACGTCAGACACCTGTCGACAGCCCA
GATGACTCAACTCTCAGTGAAAGTGCCAATCAGGTCTTTCTGGGTTTTACATATGTGGCT
CCATCTGTACTTGAAAGTGTGAAAGAAAAGTTTTCCTTTGAACCAAAAATCCGATCACCT
CGAAGATTTATTGGCAGCCCACGAACACCTGTCAGCCCAGTCAAATTTTCTCCTGGGGAT
TTCTGGGGAAGAGGTGCTTCGGCCAGCACAGCAAATCCTCAGACACCTGTGGAATACCCA
ATGGAAACAAGTGGCATAGAGCAGATGGATGTGACAATGAGTGGGGAAGCATCGGCACCA
CTTCCAATACGACAGCCGAACTCTGGGCCATACAAAAAACAAGCTTTTCCCATGATCTCC
AAACGGCCAGAGCACCTGCGTATGAATCTATGA
5' Read Nucleotide Sequence
>OriGene 5' read for NM_003161 unedited
GCGTCGAAATTTGTATACGACTCATATAGGGCGGCCGCGAATTCGCACGAGGCCTCGTGC
CGAATTCGGCACGAGGAAGCAGCCGGTGATGGCGGCAGCGGCTGTGGTGGCTGCGGCGGG
TCCGGGCCCATGAGGCGACGAAGGAGGCGGGACGGCTTTTACCCAGCCCCGGACTTCCGA
GACAGGGAAGCTGAGGACATGGCAGGAGTGTTTGACATAGACCTGGACCAGCCAGAGGAC
GCGGGCTCTGAGGATGAGCTGGAGGAGGGGGGTCAGTTAAATGAAAGCATGGACCATGGG
GGAGTTGGACCATATGAACTTGGCATGGAACATTGTGAGAAATTTGAAATCTCAGAAACT
AGTGTGAACAGAGGGCCAGAAAAAATCAGACCAGAATGTTTTGAGCTACTTCGGGTACTT
GGTAAAGGGGGCTATGGAAAGGTTTTTCAAGTACGAAAAGTAACAGGAGCAAATACTGGG
AAAATATTTGCCATGAAGGTGCTTAAAAAGGCAATGATAGTAAGAAATGCTAAAGATACA
GCTCATACAAAAGCAGAACGGAATATTCTGGAGGAAGTAAAGCATCCCTTCATCGTGGAT
TTAATTTATGCCTTTCAGACTGGTGGAAAACTCTACCTCATCCTTGAGTATCTCAGTGGA
GGAGAACTATTTATGCAGTTAGAAAGAGAGGGAATATTTATGGAAGACACTGCCTGGCTT
GAGTGGAACGCTCTTCACACCAGTTGTTCCTAACAAAACATTCTTCATGCGGCTTTTCTT
CCCTGGAATGCTTTTACTTGGCAGAAATCTCCATGCCTTTGGGGCATTTACATCAAGGGG
ATCATCTAACGAGACCCTGAACCGGGGAATTTCATGCCTTATTCCCCAAGGTCATGTGAA
ACTACCAAACTTTGGGCTTTGCAAAGAN
3' Read Nucleotide Sequence
>OriGene 3' read for NM_003161 unedited
TGGACCGCGGCCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTAACAATGATTCAT
TTGCATTTTATTATTTCACCAAGAGAAGAAACAGAAGTTGTCTGGCTTTCTTCACACCAA
CCAATAATTTCGCATTTTAAAGTTTGGGATGTTTTTCATAATGAGCTGAATCAAAAATCT
ATTTGAAAAATATATATTTATATAAAAAAAGATTCAGGTTGTTTGCACGTAAAACATCAA
TTGGTAAGTTTCTTTTGTCTTTGCTTCCATTTTGCTGGAAAAAGTTTGACCAAGCTTGCA
TGCTAATTTGTCCTTAGTTGCAAGTATTATAGGCAATTTTGTACTTTGCCTAATGAAAGG
ATAACCCTTCTTCAACACAATCAGAACTCAACAGTGATTCAGAAGCAACATCCTACCCTT
AATACTGTCAGTTTCGAGTCATCAACATGAAAATCCTTGATAAGGTTGAGAAGATGTCGC
GAGGAATCAATTAATTGATGTGCCTAAGAGTTCAGCAATACTATTTTGCTTTAAGTTTTT
TTTTGCACCATTGATTGATTTTTTAAAATCCACGTTTATTTTTCCTGTGTCTGAAGTGTT
CTATGTAATGACATTGACTCTCTGAAACTGTCATTNTGAGTCGTTTCACCTTGCAGGATG
CTCACACATCTCCCTCTCCACCTTTTTTGCCTTAAATTCATTAAAAGCATTGCTCTGTCA
TAGATTCATACGCAGGTGCTCTGGCCGTTTGGAGATCATGGGAAAAAGCTTGTTTTTGTA
TGGCCCANAGTTCGCTGTCGTATTGGAAGTGTGCCGATGCCTCCCCCTCATTGCACCATC
CTCTGCTCTATGCCACTGTTCCATTGGTATCCCACAGTGTCTGAAGATTTGCTGTGCTGC
CCGAACCCCTCTCTCCCAAAAATCCCAGAAA
Restriction Sites NotI-NotI     
Tag Tag Free
ACCN NM_003161
ORF Size 1578 bp
Insert Size 2560
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This TrueClone was found to represent an alternative form of the specific reference to which it is associated. Its Open Reading Frame (ORF) may represent a novel form or alternative splice variant. By virtue of it being a true transcript (cDNA clone not PCR product), it provides a biologically relevant copy of its mRNA template. For more details, please evaluate the sequence information provided on this website or contact our customer care specialists.
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reference Data
RefSeq NM_003161.2, NP_003152
RefSeq Size 5332
RefSeq ORF 1578
Locus ID 6198
Cytogenetics 17q23.1
Domains pkinase, pkinase_C, TyrKc, S_TKc
Protein Families Protein Kinase, Druggable Genome
Protein Pathways ErbB signaling pathway, mTOR signaling pathway, TGF-beta signaling pathway, Fc gamma R-mediated phagocytosis, Insulin signaling pathway, Acute myeloid leukemia
Gene Summary This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17. [provided by RefSeq, Jan 2013].
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.