AKAP6 (NM_004274) Human Untagged Clone

CAT#: SC117472

AKAP6 (untagged)-Human A kinase (PRKA) anchor protein 6 (AKAP6)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: AKAP6
• Synonyms: ADAP6; ADAP100; AKAP100; mAKAP; PRKA6
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_004274 edited
  GCACGAGGGTCACAGCATCATGCAGCAGGTCAAACAAGGCATCTCCTAGTATTGCATCCT
  ACAGATGTGCTGTAAACATCAAAAGAAGACGGTGGGATCAGGAGATGCTGTTTTGGAAAG
  AAGTGAGGTTTAGACTTCTCCATGTTAACCATGAGCGTGACACTTTCCCCCCTGAGGTCA
  CAGGACCTGGATCCCATGGCTACTGATGCTTCACCCATGGCCATCAACATGACACCCACT
  GTGGAGCAGGGTGAGGGAGAAGAGGCAATGAAGGACATGGACTCTGACCAGCAGTATGAA
  AAGCCACCCCCACTACACACAGGGGCTGACTGGAAGATTGTCCTCCACTTACCTGAAATT
  GAGACCTGGCTCCGGATGACCTCAGAGAGGGTCCGAGACCTAACCTATTCAGTCCAGCAG
  GATTCGGACAGCAAGCATGTGGATGTACATCTAGTTCAACTAAAGGACATTTGTGAAGAT
  ATTTCTGATCATGTTGAGCAAATCCATGCCCTCCTTGAAACAGAGTTCTCCCTAAAGCTG
  CTGTCTTACTCTGTCAACGTGATAGTGGACATCCACGCAGTGCAGCTCCTCTGGCACCAG
  CTTCGAGTCTCAGTGCTGGTTCTGCGGGAGCGCATTCTGCAAGGTCTGCAGGACGCCAAT
  GGCAACTACACTAGGCAGACGGACATTCTGCAAGCTTTCTCTGAAGAGACAAAAGAGGGC
  CGGCTTGATTCTCTAACAGAAGTGGATGACTCAGGACAATTAACCATCAAATGTTCTCAA
  AATTACTTGTCTCTGGATTGTGGCATTACTGCATTCGAACTGTCTGACTACAGTCCAAGT
  GAGGATTTGCTCAGTGGGCTAGGTGACATGACCTCTAGCCAAGTCAAAACCAAACCCTTT
  GACTCTTGGAGCTACAGTGAGATGGAAAAGGAGTTTCCTGAGCTTATCCGAAGTGTTGGT
  TTACTTACGGTAGCTGCTGACTCTATCTCTACCAATGGCAGTGAAGCAGTTACTGAGGAG
  GTATCTCAAGTATCTCTCTCAGTAGACGACAAAGGTGGATGTGAGGAAGACAATGCTTCT
  GCAGTCGAAGAGCAACCAGGCTTAACACTGGGGGTGTCATCATCTTCAGGAGAAGCTCTG
  ACAAATGCTGCTCAACCCTCCTCTGAGACTGTGCAGCAAGAATCCAGTTCCTCCTCCCAT
  CATGATGCAAAGAATCAGCAGCCTGTTCCTTGTGAAAATGCAACCCCCAAACGAACCATC
  AGAGATTGCTTTAATTATAACGAGGACTCTCCCACACAGCCTACATTGCCAAAAAGAGGA
  CTTTTTCTTAAAGAGGAAACTTTTAAGAATGATCTGAAAGGCAATGGTGGAAAGAGGCAA
  ATGGTTGATCTAAAGCCTGAGATGAGCAGAAGCACCCCTTCGCTAGTAGATCCTCCTGAC
  AGATCCAAACTTTGCCTGGTATTGCAGTCTTCTTACCCCAACAGCCCTTCTGCTGCCAGC
  CAGTCTTATGAGTGTTTACACAAGGTGGGGAATGGGAACCTTGAAAACACAGTCAAATTT
  CACATTAAAGAAATTTCTTCCAGCCTGGGAAGGCTTAACGACTGCTATAAAGAGAAATCT
  CGACTTAAAAAGCCACACAAGACCTCAGAAGAGGTGCCTCCATGCCGAACACCTAAACGG
  GGGACTGGTTCAGGCAAACAAGCTAAAAATACAAAGAGCTCAGCAGTGCCAAATGGAGAG
  CTTTCTTATACTTCCAAGGCCATAGAGGGGCCACAAACAAATTCTGCTTCCACATCCTCA
  CTTGAGCCTTGTAATCAGAGAAGTTGGAATGCCAAATTGCAATTGCAGTCAGAAACATCC
  AGTTCACCAGCTTTTACTCAGAGCAGTGAATCCTCTGTTGGCTCAGACAACATCATGTCT
  CCGGTGCCACTTCTTTCAAAACACAAAAGCAAAAAAGGTCAAGCCTCCTCTCCAAGTCAC
  GTCACTAGGAATGGTGAGGTTGTGGAGGCCTGGTATGGCTCTGATGAATACCTAGCACTG
  CCCTCTCACCTTAAGCAGACAGAAGTATTGGCTTTGAAGTTGGAAAACCTAACAAAGCTT
  CTGCCTCAGAAACCCAGAGGAGAAACCATCCAGAATATTGATGACTGGGAACTGTCTGAA
  ATGAATTCAGATTCTGAAATCTATCCAACCTATCATGTCAAAAAGAAGCATACAAGGCTA
  GGCAGGGTGTCTCCAAGCTCATCTAGTGACATAGCCTCTTCACTAGGGGAGAGCATTGAA
  TCTGGGCCCCTGAGTGACATTCTTTCTGATGAGGAGTCCAGTATGCCTCTCGCTGGCATG
  AAAAAGTATGCTGATGAGAAGTCAGAAAGAGCTTCATCCTCTGAGAAAAATGAGAGCCAT
  TCTGCCACTAAATCAGCTTTAATTCAGAAACTGATGCAAGATATTCAGCACCAAGACAAC
  TATGAAGCCATATGGGAAAAAATAGAGGGGTTTGTAAACAAACTGGATGAATTCATTCAA
  TGGTTAAATGAAGCCATGGAAACTACAGAGAATTGGACTCCCCCTAAAGCAGAGATGGAT
  GACCTTAAACTGTATCTGGAGACACACTTGAGTTTTAAGTTGAATGTAGACAGTCATTGT
  GCTCTCAAGGAAGCTGTGGAGGAGGAAGGACACCAACTTCTTGAGCTTATTGCATCTCAC
  AAAGCAGGACTGAAGGACATGCTGCGGATGATTGCAAGTCAATGGAAGGAGCTGCAGAGG
  CAAATCAAACGGCAGCACAGCTGGATTCTCAGGGCTCTGGATACCATCAAAGCCGAGATA
  CTGGCTACTGATGTGTCTGTGGAGGATGAGGAAGGGACTGGAAGCCCCAAGGCTGAGGTT
  CAACTATGCTACCTGGAAGCACAAAGAGATGCTGTTGAGCAGATGTCCCTCAAGCTGTAC
  AGCGAGCAGTATACCAGCAGCAGCAAGCGAAAGGAAGAGTTTGCTGATATGTCAAAAGTT
  CATTCAGTGGGAAGCAATGGGCTTCTGGACTTTGATTCAGAATATCAGGAGCTCTGGGAT
  TGGCTGATTGACATGGAGTCCCTTGTGATGGACAGCCACGACCTGATGATGTCAGAGGAG
  CAGCAGCAGCATCTTTACAAGCGATACAGTGTGGAAATGTCCATCAGACACCTGAAAAAG
  ACGGAGCTGCTTAGTAAGGTTGAAGCTTTGAAGAAAGGTGGCGTTTTACTACCAAATGAT
  CTCCTTGAAAAAGTGGATTCAATTAATGAAAAATGGGAACTGCTTGGGAAAACCCTAGGA
  GAGAAGATCCAGGACACAATGGCAGGGCACAGTGGGTCGAGTCCACGTGACCTGCTCTCT
  CCTGAAAGTGGAAGCCTGGTAAGGCAGCTGGAGGTCAGGATCAAAGAACTGAAAGGATGG
  CTAAGAGATACAGAGCTTTTCATCTTCAATTCCTGTCTGAGACAAGAAAAGGAAGGAACA
  ATGAATACTGAGAAACAACTGCAATACTTTAAGTCCCTCTGTCGTGAAATCAAGCAACGA
  CGTCGAGGAGTTGCCTCCATTCTGCGACTATGCCAGCATCTTTTGGATGACCGGGAGACT
  TGCAATCTGAATGCAGATCACCAGCCCATGCAGCTGATCATTGTAAATCTTGAAAGAAGG
  TGGGAAGCCATTGTCATGCAAGCCGTCCAGTGGCAAACACGTCTACAAAAGAAGATGGGA
  AAGGAATCTGAGACTTTGAATGTGATTGATCCTGGCTTGATGGACCTAAATGGGATGAGT
  GAGGATGCCCTGGAATGGGATGAAATGGACATAAGTAACAAGTTAATTAGTTTGAATGAG
  GAATCAAATGACCTTGATCAAGAACTCCAACCTGTTATCCCTTCCTTGAAGCTTGGAGAG
  ACAAGTAATGAGGACCCTGGTTATGACGAGGAGGCTGATAACCATGGGGGATCTCAGTAT
  GCCTCAAATATTACTGCCCCCTCTAGTCCACACATTTACCAGGTGTACAGCCTCCACAAT
  GTTGAACTCTATGAGGACAACCACATGCCATTTCTGAAAAACAATCCAAAGGTCACTGGC
  ATGACACAGCCTAATGTTTTAACTAAGAGTCTCAGTAAAGACTCTTCATTTTCATCTACC
  AAATCTTTGCCAGATCTTCTAGGTGGTTCCAATTTGGTAAAGCCCTGCGCATGTCATGGA
  GGAGACATGAGCCAGAATTCAGGCAGTGAGAGTGGAATTGTCAGTGAAGGAGACACAGAA
  ACCACTACCAACTCTGAAATGTGCTTGCTCAATGCAGTGGATGGGTCCCCAAGTAACCTT
  GAAACTGAACATCTGGACCCACAAATGGGAGATGCAGTTAACGTGTTAAAGCAAAAATTT
  ACAGATGAGGGGGAAAGCATTAAGCTTCCAAATAGCTCTCAGTCGTCCATTTCACCAGTG
  GGTTGTGTAAATGGAAAAGTTGGAGATTTAAACAGTATTACCAAACATACCCCTGACTGT
  TTGGGAGAAGAATTACAAGGAAAACATGATGTGTTTACATTTTATGATTACTCATACCTC
  CAAGGCTCAAAACTCAAATTACCAATGATAATGAAACAGTCACAAAGCGAAAAAGCGCAT
  GTGGAGGATCCCCTGCTTCGTGGTTTTTATTTTGATAAAAAATCATGCAAATCTAAACAT
  CAGACTACAGAGTTACAACCAGATGTACCTCCCCATGAAAGGATTTTGGCAAGTGCATCT
  CATGAAATGGATCGCATTTCATATAAAAGTGGCAATATAGAAAAGACATTCACTGGCATG
  CAGAATGCCAAACAGCTCTCCCTTTTATCTCATAGTTCATCTATTGAGTCCCTTTCTCCA
  GGGGGTGATTTATTTGGATTGGGCATCTTTAAAAATGGCAGTGACAGCCTCCAGCGAAGC
  ACTTCTTTAGAAAGTTGGTTGACTTCCTATAAAAGCAATGAAGATCTCTTTAGCTGTCAC
  AGCTCTGGGGATATAAGCGTGAGCAGTGGCTCAGTTGGTGAACTAAGTAAAAGAACATTA
  GATCTCCTGAATCGTTTGGAGAATATCCAGAGCCCCTCAGAGCAAAAGATAAAACGAAGT
  GTTTCTGATATCACTCTTCAAAGCAGTTCCCAAAAGATGTCCTTTACTGGCCAGATGTCA
  TTGGACATAGCATCTTCTATCAATGAAGACTCAGCGGCATCTCTAACAGAACTTAGCAGC
  AGTGACGAGCTCTCTCTTTGCTCAGAGGATATTGTGTTACACAAGAACAAGATCCCGGAA
  TCGAATGCATCGTTCAGGAAGCGTCTGACTCGTTCAGTGGCTGATGAAAGCGATGTCAAT
  GTCAGCATGATTGTTAATGTCTCTTGCACCTCTGCTTGCACTGATGATGAAGATGACAGC
  GACCTGCTCTCCAGCTCTACCCTTACCTTGACTGAAGAAGAGCTGTGCATCAAAGATGAG
  GATGACGACTCCAGTATTGCAACAGATGATGAAATTTATGAAGACTGCACCTTGATGTCA
  GGGCTAGACTACATAAAGAATGAATTACAGACCTGGATTAGGCCAAAATTGTCTTTGACA
  AGAGATAAGAAAAGGTGCAATGTCAGTGATGAGATGAAGGGCAGTAAAGATATAAGTAGC
  AGTGAGATGACCAATCCCTCTGATACTCTGAATATTGAGACCCTTCTAAATGGCTCTGTA
  AAACGTGTCTCTGAAAATAATGGAAATGGTAAGAATTCATCTCATACCCATGAGTTAGGG
  ACAAAGCGTGAAAATAAGAAAACTATTTTCAAAGTTAATAAAGATCCATATGTGGCTGAC
  ATGGAAAATGGCAATATTGAAGGTATTCCAGAAAGGCAAAAGGGCAAACCGAATGTGACT
  TCAAAGGTATCAGAAAATCTTGGTTCACATGGGAAAGAGATTTCAGAGAGTGAGCATTGT
  AAGTGTAAAGCACTTATGGATAGTTTAGATGATTCAAATACTGCTGGCAAGGAATTTGTT
  TCCCAAGATGTTAGACATCTTCCAAAGAAATGTCCAAATCACCACCATTTTGAAAATCAA
  AGCACTGCCTCTACTCCCACTGAGAAGTCTTTCTCAGAACTGGCTTTAGAAACCAGGTTT
  AACAACAGACAAGACTCTGATGCACTGAAATCATCTGATGATGCACCGAGTATGGCTGGA
  AAATCTGCTGGTTGTTGCCTAGCACTTGAACAAAACGGAACAGAGGAAAATGCTTCTATC
  AGCGACATTTCCTGTTGCAACTGTGAGCCAGATGTTTTCCATCAAAAAGATGCCGAAGAT
  TGTTCAGTACACAACTTTGTTAAGGAAATCATTGACATGGCTTCGACAGCCCTAAAAAGT
  AAATCTCAACCTGAAAACGAGGTGGCTGCTCCTACTTCATTAACTCAAATCAAGGAGAAA
  GTGTTGGAGCATTCTCACCGGCCCATCCAGCTGAGAAAAGGGGACTTTTATTCGTACTTA
  TCTCTCTCATCTCATGACAGTGATTGTGGGGAGGTCACCAATTACATAGAAGAGAAAAGC
  AGCACTCCATTGCCACTAGACACCACTGACTCGGGCTTAGATGACAAGGAAGATATTGAA
  TGCTTTTTTGAGGCCTGTGTTGAGGGTGACTCTGATGGAGAGGAGCCTTGTTACTCTAGT
  GCTCCTCCAAATGAATCTGCAGTTCCCAGCGAAGCTGCAATGCCACTACAAGCAACAGCA
  TGTTCTTCTGAGTTCAGTGATAGTTCTCTTTCAGCTGATGATGCAGATACAGTGGCTCTT
  TCAAGTCCTTCCTCTCAGGAAAGAGCTGAGGTTGGAAAGGAAGTGAATGGTTTGCCCCAA
  ACTTCCAGTGGCTGTGCAGAAAACTTAGAGTTTACTCCTTCAAAGCTTGACAGTGAAAAG
  GAAAGTTCCGGAAAACCAGGTGAATCTGGAATGCCAGAAGAACATAATGCTGCTTCAGCC
  AAATCTAAAGTTCAAGACCTCTCCTTGAAGGCAAATCAGCCAACAGACAAGGCCGCATTG
  CATCCCAGCCCCAAAACTTTAACCTGTGAAGAAAATCTTCTAAACCTTCATGAAAAACGA
  CATAGAAATATGCATAGGTAGAATGTACCCCCTCCCCAAGCATGAAAATCATCTCACTGA
  AAGATACGCCTGGCTGCAACTCAGGGGTGGCCTCATCCTCCCGCCCTGGGCTGG
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_004274 unedited
  GGGCCTCAGGTTGCCCGTTCCCGCTTAGGGCGGTAGGCGTGTCCGGTGGGNAGGTCTATA
  TAAGCAGAGCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGC
  CGCGAATTCGGCACGAGGGTCACAGCATCATGCAGCAGGTCAAACAAGGCATCTCCTAGT
  ATTGCATCCTACAGATGTGCTGTAAACATCAAAAGAAGACGGTGGGATCAGGAGATGCTG
  TTTTGGAAAGAAGTGAGGTTTAGACTTCTCCATGTTAACCATGAGCGTGACACTTTCCCC
  CCTGAGGTCACAGGACCTGGATCCCATGGCTACTGATGCTTCACCCATGGCCATCAACAT
  GACACCCACTGTGGAGCAGGGTGAGGGAGAAGAGGCAATGAAGGACATGGACTCTGACCA
  GCAGTATGAAAAGCCACCCCCACTACACACAGGGGCTGACTGGAAGATTGTCCTCCACTT
  ACCTGAAATTGAGACCTGGCTCCGGATGACCTCAGAGAGGGTCCGAGACCTAACCTATTC
  AGTCCAGCAGGATTCGGACAGCAAGCATGTGGATGTACATCTAGTTCAACTAAAGGACAT
  TTGTGAAGATATTTCTGATCATGTTGAGCAAATCCATGCCCTCCTTGAAACAGAGTTCTC
  CCTAAAGCTGCTGTCTTACTCTGTCAACGTGATAGTGGACATCCACGCAGTGCAGCTCCT
  CTGGCACCAGCTTCGAGTCTCAGTGCTGGTTCTGCGGGAGCGCATTCTGCAAAGTCTGCA
  NGACGCCCATGGNCACTACACTANGCAGACAGACATTCTGCAAGCTTTCTCTGAAGAGAC
  AAAAAGAGGCCAGCTTGATTCTCTACAGAAGTGGATGACNTCAGACATTAACCATCAAAT
  GTCTCAAA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_004274 unedited
  CATAATCTGTGTTTATTTATGCCATTTTAATTACCATGCAATCTAATGGATTTAAGGCTT
  ATATTTTCCACATCACTAGACATCACAAACATGAAAGCATTTTATACTGTCATTATACAT
  CAATGTTTGTACTTGGTTATACATATATACAGAAATTATTCACACATCTTAACCTTGCTA
  TTTCCTCCTTTCAAACCAACATAATTTTACCGTGAAAGCAGCTTTTTAATAAATGGTATA
  AGAAATACAGCAAGGCACACTTTTTTAAAAAACTTTTTTCTCATTACCACCTCAAGAAGC
  ATAAAAAATGAAAATGTTGTACATAATTCAATAGTAGAATGTCACCAGTTTATAATATAC
  AACACCATATGGTTGTTTCTTGAAATGCTGCATAGATTATTTTTTAAATGAAATAAATAA
  AATGGCGCTTTTAATAGTTGCTTAATTTTGAAAGAAGGACCAGTGTTTCTTCTCTATGCT
  GCAACCAATTCAAATGTTGGCTTTTTAGGTAAAACTCTTTAATAAACACAGTCATTATAC
  CGGTAAAAAAAAAATCAGATTGATACATGAAATTGGGCAAGGACCTGGGGGGGGGGGTAC
  TTCTAAACAGGACGATTTAATGCACCTACCCGTTGGGGGAACTGGATAAATTTTAAAAAT
  TGCAGCGAAAGGAGGAGGCAAAAATCAAAATTTTTCTCGTGAAACACAGGGTGGGTCCAG
  GTAACCTCTGGAACAGACATCCTGGGGAACAACNCACCCTCGTTCACATTTAAAAATAAT
  CCCCAAATACAAAACACGGCCACACTTCTAAGTAAAAGGTGTCGGGGGGAGAAACCCCTT
  CGAGTGGTGTACTTTCGTTGCTCGGATATCTCTTTAGCACACTTNCTGCCCACATTCGTA
  GGCTCCTCTTCCCTCCCTCTTCTCGCGCCCTTTTNCCACCCACGTTCCTTTCCTCGCTCN
  CCTGTCCGGCCCCTTCTCGCCCTGTGTGCGGGCCTCCTCCCGCCTGTTCACCTTACTCTC
  CCGCCCACCGCGGCGAACTACTAAT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_004274
• Insert Size: 8940 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_004274.3, NP_004265.3
• RefSeq Size: 10342 bp
• RefSeq ORF: 6960 bp
• Locus ID: 9472
• UniProt ID: Q13023
• Cytogenetics: 14q12
• Domains: spectrin
• Protein Families: Druggable Genome
• Gene Summary: The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is highly expressed in various brain regions and cardiac and skeletal muscle. It is specifically localized to the sarcoplasmic reticulum and nuclear membrane, and is involved in anchoring PKA to the nuclear membrane or sarcoplasmic reticulum. [provided by RefSeq, Jul 2008]