MCP4 (CCL13) (NM_005408) Human Untagged Clone

CAT#: SC116797

CCL13 (untagged)-Human chemokine (C-C motif) ligand 13 (CCL13)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MCP4
• Synonyms: CKb10; MCP-4; NCC-1; NCC1; SCYA13; SCYL1
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC116797 sequence for NM_005408 edited (data generated by NextGen Sequencing)
  ATGAAAGTCTCTGCAGTGCTTCTGTGCCTGCTGCTCATGACAGCAGCTTTCAACCCCCAG
  GGACTTGCTCAGCCAGATGCACTCAACGTCCCATCTACTTGCTGCTTCACATTTAGCAGT
  AAGAAGATCTCCTTGCAGAGGCTGAAGAGCTATGTGATCACCACCAGCAGGTGTCCCCAG
  AAGGCTGTCATCTTCAGAACCAAACTGGGCAAGGAGATCTGTGCTGACCCAAAGGAGAAG
  TGGGTCCAGAATTATATGAAACACCTGGGCCGGAAAGCTCACACCCTGAAGACTTGA
  
  Clone variation with respect to NM_005408.2
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_005408 unedited
  TGTCAGCATTTGTATACGACTCACTATAGGCGGCCGCGAATCCCGGGNAATCGTCGACCC
  ACGCGTCCGAAGAAACATTGTGAAATCTCCAACTCTTAACCTTCAACATGAAAGTCTCTG
  CAGTGCTTCTGTGCCTGCTGCTCATGACAGCAGCTTTCAACCCCCAGGGACTTGCTCAGC
  CAGATGCACTCAACGTCCCATCTACTTGCTGCTTCACATTTAGCAGTAAGAAGATCTCCT
  TGCAGAGGCTGAAGAGCTATGTGATCACCACCAGCAGGTGTCCCCAGAAGGCTGTCATCT
  TCAGAACCAAACTGGGCAAGGAGATCTGTGCTGACCCAAAGGAGAAGTGGGTCCAGAATT
  ATATGAAACACCTGGGCCGGAAAGCTCACACCCTGAAGACTTGAACTCTGCTACCCCTAC
  TGAAATCAAGCTGGAGTACGTGAAATGACTTTTCCATTCTCCTCTGGCCTCCTCTTCTAT
  GCTTTGGAATACTTCTACCATAATTTTCAAATAGGATGCATTCGGTTTTGTGATTCAAAA
  TGTACTATGTGTTAAGTAATATTGGCTATTATTTGACTTGTTGCTGGTTTGGAGTTTATT
  TGAGTATTGCTGATCTTTTCTAAAGCAAGGCCTTGAGCAAGTAGGTTGCTGTCTCTAAGC
  CCCCTTCCCTTCCACTATGAGCTGCTGGCAGTGGGTTTGTATTCGGTTCCCAGGGGTTGA
  GAGCATGCCTGTGGGAGTCATGGACATGAAGGGATGCTGCAATGTAAGAAGGAGAGCTCT
  TTGTGAATGTGAAGTGTTGCTAAATATGTTATTGTGGAAAGAGAATGCAATAGTAGGACT
  GCTGACATTTTGCAGAAAATACATTTAATTAAAATCTCCTAAAAN
  
• Restriction Sites: Please inquire
• ACCN: NM_005408
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_005408.2, NP_005399.1
• RefSeq Size: 861 bp
• RefSeq ORF: 297 bp
• Locus ID: 6357
• UniProt ID: Q99616
• Cytogenetics: 17q12
• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Chemokine signaling pathway, Cytokine-cytokine receptor interaction, NOD-like receptor signaling pathway
• Gene Summary: This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils, but not neutrophils. This chemokine plays a role in accumulation of leukocytes during inflammation. It may also be involved in the recruitment of monocytes into the arterial wall during artherosclerosis. [provided by RefSeq, Sep 2014]