HMGN2 (NM_005517) Human Untagged Clone

CAT#: SC116703

HMGN2 (untagged)-Human high mobility group nucleosomal binding domain 2 (HMGN2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: HMGN2
• Synonyms: HMG17
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_005517, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGCCCAAGAGAAAGGCTGAAGGGGATGCTAAGGGAGATAAAGCAAAGGTGAAGGACGAACCACAGAGAA
  GATCCGCGAGGTTGTCTGCTAAACCTGCTCCTCCAAAGCCAGAGCCCAAGCCTAAAAAGGCCCCTGCAAA
  GAAGGGAGAGAAGGTACCCAAAGGGAAAAAGGGAAAAGCTGATGCTGGCAAGGAGGGGAATAACCCTGCA
  GAAAATGGAGATGCCAAAACAGACCAGGCACAGAAAGCTGAAGGTGCTGGAGATGCCAAGTGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_005517 unedited
  AAAATCATGTACTTCTCTATGAGGGNCGGCACGCCCAATTCGCACGAGGAAGAGGCGAGA
  ACGACCCCCGGACCGACCAAAGCCCGCGCGCCGCTGCATCCCGCGTCCAGCACCTACGTC
  CCGCTGCCGTCGCCGCCGCCACCATGCCCAAGAGAAAGGCTGAAGGGGATGCTAAGGGAG
  ATAAAGCAAAGGTGAAGGACGAACCACAGAGAATTATCCGCGAGGTTGTCTGCTAAACCT
  GCTCCTCCAAAGCCAGAGCCCAAGCCTAAAAAGGCCCCTGCAAAGAAGGGAGAGAAGGTA
  CCCAAAGGGAAAAAGGGAAAAGCTGATGCTGGCAAGGAGGGGAATAACCCTGCAGAAAAT
  GGAGATGCCAAAACAGACCAGGCACAGAAAGCTGAAGGTGCTGGAGATGCCAAGTGAAGT
  GTGTGCATTTTTGATAACTGTGTACTTCTGGTGACTGTACAGTTTGAAATACTATTTTTT
  ATCAAGTTTTATAAAAATGCAGAATTTTGTTTTACTTTTTTTTTTTTTTTAAAAGCTATG
  TTGTTAGCACACAGAACACTTCATTGTTGTTTTTGGGGGAAGGGGCATATGTCACTAATA
  GAATGTCTCCAAAGCTGGATTGATGTGGAGAAAACACCTTTCCCTTCTAGTTTTGAGAGA
  CTTCCTCTTGGCTCCCAGGAGGAGGGATTCCCTGACTTTGACACACATGGCCACCTTGGC
  ACAAAAGCCTTGTGGTATAGAAAAACAAATTTGNTTTTATGTCCTCTTCTCCCTTTCCAT
  CTTTCAGCATAGACTTAACTCCCTTAAGCCAGACATCTGTTGAGACCTGACCCCTAGTCA
  TTGGNTACCAGTGTGTCAGGCAATCTGGACTTTCCAGTGATGCCACTGAGATGGCACTGT
  CAAAGAGCAGNGGTCCATTTCTAGATGNGGATCTCAGATAATNCTGCCATTTCATTNCAC
  TCCTGAAGA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_005517
• Insert Size: 3460 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_005517.2, NP_005508.1
• RefSeq Size: 1306 bp
• RefSeq ORF: 273 bp
• Locus ID: 3151
• UniProt ID: P05204
• Cytogenetics: 1p36.11
• Domains: HMG14_17
• Protein Families: Druggable Genome, Transcription Factors
• Gene Summary: The protein encoded by this gene binds nucleosomal DNA and is associated with transcriptionally active chromatin. Along with a similar protein, HMGN1, the encoded protein may help maintain an open chromatin configuration around transcribable genes. The protein has also been found to have antimicrobial activity against bacteria, viruses and fungi. [provided by RefSeq, Oct 2014]