ILRUN (NM_024294) Human Untagged Clone

CAT#: SC112260

C6orf106 (untagged)-Human chromosome 6 open reading frame 106 (C6orf106), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ILRUN
• Synonyms: C6orf106; dJ391O22.4; FP852
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_024294, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGAGGGCATGGACGTAGACCTGGACCCGGAGCTGATGCAGAAGTTCAGCTGCCTGGGCACCACCGACA
  AGGACGTGCTCATCTCCGAGTTCCAGAGGCTGCTCGGCTTCCAGCTCAATCCTGCCGGTTGCGCCTTCTT
  CCTGGACATGACCAACTGGAACCTACAAGCAGCAATTGGCGCCTATTATGACTTTGAGAGCCCAAACATC
  AGTGTGCCCTCTATGTCCTTTGTTGAAGATGTCACCATAGGAGAAGGGGAGTCAATACCTCCGGATACTC
  AGTTTGTAAAAACATGGCGGATCCAGAATTCTGGGGCAGAGGCCTGGCCTCCAGGGGTTTGTCTTAAATA
  TGTCGGGGGAGACCAATTTGGACATGTGAACATGGTGATGGTGAGATCGCTAGAGCCCCAAGAGATTGCA
  GATGTCAGCGTCCAGATGTGCAGCCCCAGCAGAGCAGGAATGTATCAGGGACAGTGGCGGATGTGCACTG
  CTACAGGACTCTACTATGGAGATGTCATCTGGGTGATTCTCAGTGTGGAGGTGGGTGGACTTTTAGGAGT
  AACGCAGCAGCTGTCATCTTTTGAAACGGAGTTCAACACACAGCCGCATCGTAAGGTAGAAGGAAACTTC
  AACCCTTTTGCCTCTCCCCAAAAGAACCGACAATCAGATGAAAACAACTTAAAAGACCCTGGGGGCTCCG
  AGTTCGACTCGATCAGCAAAAACACATGGGCTCCTGCTCCTGACACATGGGCTCCTGCTCCTGACCAAAC
  TGAGCAAGACCAGAATAGACTGTCACAGAACTCTGTAAATCTGTCTCCCAGCAGTCACGCAAACAACTTA
  TCAGTAGTGACTTACAGTAAGGGGCTCCATGGGCCTTACCCCTTCGGCCAGTCTTAA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_024294 unedited
  GGTTCACTATTTTGTAACACGACTCACTATAGGGCGGCCGCGCAATTCGCACGAGGCGGC
  GGCGCGGCGGCGGCTTGGTTGTGAAGAGGCGGGGAAGCGGGTGTCCGGTCCCCGCCATGG
  AGGGCATGGACGTAGACCTGGACCCGGAGCTGATGCAGAAGTTCAGCTGCCTGGGCACCA
  CCGACAAGGACGTGCTCATCTCCGAGTTCCAGAGGCTGCTCGGCTTCCAGCTCAATCCTG
  CCGGTTGCGCCTTCTTCCTGGACATGACCAACTGGAACCTACAAGCAGCAATTGGCGCCT
  ATTATGACTTTGAGAGCCCAAACATCAGTGTGCCCTCTATGTCCTTTGTTGAAGATGTCA
  CCATAGGAGAAGGGGAGTCAATACCTCCGGATACTCAGTTTGTAAAAACATGGCGGATCC
  AGAATTCTGATGTCATCTGGGTGATTCTCAGTGTGGAGGCGGGTGGACTTTTACGAGTAA
  CGCAGCAGCTGTCCATCTTTTGAAACGGAGTTCAACACACAGCCGCATCGCAAGGTAGAA
  GGAAACTTCAACCCTTTTGCCTCTCCTCAAAAGAACCGACAATCAGATGAAAACAACTCA
  TAAGACCCTGCGGGCTTCGAGNTCCAATCGATCAGCAAAAAAACATTGGGCTCCTGCCTC
  CTGACACATGGGCTTCCTGCTTCTTGACCAAACTGAGCAAGACCAGAATACACTGTCCCA
  GAACCCTGCAATCCGTCTCCCATTACTCCTGTCCACCCCTTATCGCATCGCCTTACAGGA
  ACGGGCTCCATGGGCCTACCCCTTCCGCCACCCTTACCCGGTGGTCACCCGAACAAAATT
  AACAACGACAGAGGGCCGACTTTGGGGGGTTGGGCAGGGGTTTTCTGGAATGCCCACCAC
  TCGCACAATCCCGGT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_024294 unedited
  GGCCGCAATCTANAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTGGAAGAAAACAATTT
  TAATTGTTACAAGGGTGTGCAGAAGGACACCTCTCAGGCTTAAAAAATCCCACGTCACCC
  GAGATCTATCCTCAAGGCTTCCTCTGCTGGCCACACAGGGAAGTTTGGTCTTCAGAGAGG
  TTCTGATGCTAACAAGCCACAGGGTTGACGAATACAAATGTCAAAGGTGTAAATCAACAG
  AAGATTAAAGAGAAAAGAGGAGGAAAAGGGTGATAACTCATTGGCTGATGCCATTAAAAA
  CAAATGGGGTCAGAGACTTCTGGAGTCATGTGGCAGGGCAGATGTACTCCTGTAGCACTG
  ATCCGCAGAGTCCTCAAACATGCCACGCCAACTTTTCACCTGAATCTCTTCCAGAACAAG
  CACTATTCTATAAAGAATATGTTATCCCTTATTTAAAAAAATAAAAGTGGGGAAAGAGGG
  AAAAAAATTAACATGTGCTCAAAACTACAACCTTTCTGTAGGCAAAATAATTTTTGTTTA
  AAAAGATGGCTTTTTTTCCCCCATTTTAAACTTTTTCCCCCTTCCCGAGTAACCTAATGA
  CTTGTTAGACTGATGCCTATAACAAAACCCAAAGTGGCTACATGGATTTCTTCTTGGTAG
  CCTCAACACCATTCCTGTGATTCAGCATTCACACATGCATACTGAGTTNACTCAAAACTA
  GNCTGTTCTGCTTCTTCCTCTTCTTCCCGGATGAGAGGGGGTCAGAGCCCAGGGTCTGTG
  CGATGTGGTCTGCATCCANAGAACCCCTTGCCCTACCCCCAAGTCAGCCCTCTGCCTTTT
  TGTATTTNTCTCCTGCTGACCCCGTTTAAAACTGGCCGANGGGTAGGCCCATGNACCCCT
  ACTGTAGTCACTCTGTAAANTTGTTGCTGACTGTGGAAGAAGATTACGAGTCTGTGAATC
  TTTCTGG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_024294
• Insert Size: 1680 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_024294.2, NP_077270.1
• RefSeq Size: 4430 bp
• RefSeq ORF: 897 bp
• Locus ID: 64771
• UniProt ID: Q9H6K1
• Cytogenetics: 6p21.31
• Gene Summary: Negative regulator of innate antiviral response. Blocks IRF3-dependent cytokine production such as IFNA, IFNB and TNF (PubMed:29802199). Interacts with IRF3 and inhibits IRF3 recruitment to type I IFN promoter sequences while also reducing nuclear levels of the coactivators EP300 and CREBBP (PubMed:29802199).[UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).