Cyclophilin A(PPIA) (NM_021130) Human Untagged Clone
PPIA (untagged)-Human peptidylprolyl isomerase A (cyclophilin A) (PPIA)
|Product Name||Cyclophilin A(PPIA) (NM_021130) Human Untagged Clone|
|Synonyms||CYPA; CYPH; HEL-S-69p|
Fully Sequenced ORF
>OriGene ORF within SC111937 sequence for NM_021130 edited (data generated by NextGen Sequencing)
Clone variation with respect to NM_021130.3
5' Read Nucleotide Sequence
>OriGene 5' read for NM_021130 unedited
3' Read Nucleotide Sequence
>OriGene 3' read for NM_021130 unedited
|ORF Size||498 bp|
|OTI Disclaimer||Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at firstname.lastname@example.org or by calling 301.340.3188 option 3 for pricing and delivery.
The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
|Product Components||The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.|
|Gene Summary||This gene encodes a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. The encoded protein is a cyclosporin binding-protein and may play a role in cyclosporin A-mediated immunosuppression. The protein can also interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions. Multiple pseudogenes that map to different chromosomes have been reported. [provided by RefSeq, Jul 2008].
Transcript Variant: This variant (1) represents the shorter transcript but encodes the longer isoform (1).
|The use of this cDNA Clones has been cited in the following citations:|
BMP-2/4 and BMP-6/7 Differentially Utilize Cell Surface Receptors to Induce Osteoblastic Differentiation of Human Bone Marrow-derived Mesenchymal Stem Cells
,Karen Lavery, Pamela Swain, Dean Falb, and Moulay Hicham Alaoui-Ismaili,
J. Biol. Chem., Jul 2008; 283: 20948 - 20958.
BMP-2/4 and BMP-6/7 differentially utilize cell surface receptors to induce osteoblastic differentiation of human bone marrow derived mesenchymal stem cells
,Karen S. Lavery, Pamela M. Swain, Dean Falb, and Moulay Hicham Alaoui-Ismaili,
J. Biol. Chem., Apr 2008; 10.1074/jbc.M800850200
GATA3 upregulation associated with surface expression of CD294/CRTH2: a unique feature of human Th cells
,Umberto De Fanis, Francesca Mori, Rebecca J. Kurnat, Won Kyung Lee, Maria Bova, N. Franklin Adkinson, Jr, Vincenzo Casolaro,
Blood. 2007 May 15;109(10):4343-50.
|cDNA Clone Resources|