IGLL1 (NM_020070) Human Untagged Clone

CAT#: SC111642

IGLL1 (untagged)-Human immunoglobulin lambda-like polypeptide 1 (IGLL1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: IGLL1
• Synonyms: 14.1; AGM2; CD179b; IGL1; IGL5; IGLJ14.1; IGLL; IGO; IGVPB; VPREB2
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_020070 edited
  GAATTCGGCACGAGATGGACTGGGGTGCAATGGGACAGCTGCTGCCAGCGAGAGGGACCA
  GGGCACCACTCTCTAGGGAGCCCACACTGCAAGTCAGGCCACAAGGACCTCTGACCCTGA
  GGGCCGATGAGGCCAGGGACAGGCCAGGGGGGCCTTGAGGCCCCTGGTGAGCCAGGCCCC
  AACCTCAGGCAGCGCTGGCCCCTGCTGCTGCTGGGTCTGGCCGTGGTAACCCATGGCCTG
  CTGCGCCCAACAGCTGCATCGCAGAGCAGGGCCCTGGGCCCTGGAGCCCCTGGAGGAAGC
  AGCCGGTCCAGCCTGAGGAGCCGGTGGGGCAGCAGGTTCCTGCTCCAGCGCGGCTCCTGG
  ACTGGCCCCAGGTGCTGGCCCCGGGGGTTTCAATCCAAGCATAACTCAGTGACGCATGTG
  TTTGGCAGCGGGACCCAGCTCACCGTTTTAAGTCAGCCCAAGGCCACCCCCTCGGTCACT
  CTGTTCCCGCCGTCCTCTGAGGAGCTCCAAGCCAACAAGGCTACACTGGTGTGTCTCATG
  AATGACTTTTATCCGGGAATCTTGACGGTGACCTGGAAGGCAGATGGTACCCCCATCACC
  CAGGGCGTGGAGATGACCACGCCCTCCAAACAGAGCAACAACAAGTACGCGGCCAGCAGC
  TACCTGAGCCTGACGCCCGAGCAGTGGAGGTCCCGCAGAAGCTACAGCTGCCAGGTCATG
  CACGAAGGGAGCACCGTGGAGAAGACGGTGGCCCCTGCAGAATGTTCATAGGTTCCCAGC
  CCCGACCCCACCCAAAGGGGCCTGGAGCTGCAGGATCCCAGGGGAAGGGTCTCTCTCTGC
  ATCCCAAGCCATCCAGCCCTTCTCCCTGTACCCAGTAAACCCTAAATAAATACCCTCTTT
  GTCAACCAGAAAAAAAAAAAAAAAAAACTCGAC
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_020070 unedited
  CGCGTTCAGGCATATTTGTNAATACGAACTTTACTTTGAGGGNNCGGCCGCGNAATTCGG
  CACGAGATGGACTGGGGTGCAATGGGACAGCTGCTGCCAGCGAGAGGGACCAGGGCACCA
  CTCTCTAGGGAGCCCACACTGCAAGTCAGGCCACAAGGACCTCTGACCCTGAGGGCCGAT
  GAGGCCAGGGACAGGCCAGGGGGGCCTTGAGGCCCCTGGTGAGCCAGGCCCCAACCTCAG
  GCAGCGCTGGCCCCTGCTGCTGCTGGGTCTGGCCGTGGTAACCCATGGCCTGCTGCGCCC
  AACAGCTGCATCGCAGAGCAGGGCCCTGGGCCCTGGAGCCCCTGGAGGAAGCAGCCGGTC
  CAGCCTGAGGAGCCGGTGGGGCAGCAGGTTCCTGCTCCAGCGCGGCTCCTGGACTGGCCC
  CAGGTGCTGGCCCCGGGGGTTTCAATCCAAGCATAACTCAGTGACGCATGTGTTTGGCAG
  CGGGACCCAGCTCACCGTTTTAAGTCAGCCCAAGGCCACCCCCTCGGTCACTCTGTTCCC
  GCCGTCCTCTGAGGAGCTCCAAGCCAACAAGGCTACACTGGTGTGTCTCATGAATGACTT
  TTATCCGGGAATCTTGACGGTGACCTGGAAGGCAGATGGTACCCCCATCACCCAGGGCGT
  GGAGATGACCACGCCCTCCANACAGAGCAACAACAAGTACGCGGCCAGCAGCTACCTGAG
  CCTGACGCCCGAGCAGTGGAGGTCCCGCAGAAGCTACAGCTGCCAGGTCATGCACGAAAG
  GAGCACCGTGGAGAAGACGGTGGCCCCTGCAGAAATGTCATAGGTTCCCAGCCCCGACCC
  CACCCAAAGGGCCTGGAGCTGCAAGATCCCANGGGAAGGGTCTTCTCTGCATCCCAGCCA
  TNCAGCCTTCTNCCTGTACCCATAAACCCTAATAATACCC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_020070 unedited
  TGGGGCCCAATACCGCCTACTTTCCCCCCCCCGGAATCGTGTNCCGCGGCCGCATTTTAT
  GATCGGTTTTTTTTTTTTTTTTTTCTGGGTGACAAACAGGTTTTTATTTAGGGTTTACTG
  GGGTACAGGGTAGAAAGGGGCTGGTATGGCCTTGGGCATGCACGAGAGAGACCCTTCCCC
  TGGGATCCTGCAGCTCCAGGCCCCTTTGGGTGGGGTCGGGGCTGGGAACCTATGAACATT
  CTGCAGGGGCCACCGTCTTCTTTACTGTGCTCCCTTCGTGCATGACCTGGCAGCTGTAGC
  TTCTGCGGGACCTCCACTGCTCGGGCGTCAGGCTCAGGTAGCTGCTGGCCGCGTACTTGT
  TGTTGCTCTGTTTGGAGGGCGTGGTCATCTCCACGCCCTGGGTGATGGGGGTACCATTTG
  CCTTCCAGGTCACCGTCAAGATTCCCGGATAAAAGTCATTCATGAGACACACCAGTGTAG
  CCTTGTTGGCTTGGAGCTCCTCATAGGACGGGGGGAACAGAGTGACCGAAGGGGTGGCCT
  TGGGCTGACTTAAACGGTGAGCTGGGCCCGCTGCCAAAACACATGCCGCACTGAGTATGC
  TTGGATTGAACCCCCGGGGCCAGCACCTGGGGCCCAGTCCAGGAGCCGCGCTGGACCAGG
  ACCCTGCTTGCCCCACCGGCTCCCTCAGCTTGGACCGCTTGCTTTCTTCCAGGGGCCTCC
  AGGGGCCCAGGCCCCTGCTTTGGCATGCAATTTGTTTGGCCCCCCAGGCCATTGGTTACC
  ACGGCCAAACCCCCCACACCAAGGGCCCCCCCTTCCCTGAGGTTGGGGCCCGGCCTCCAC
  AGGGGCCTCAAGGGCCCCCTGGCCTTGGCCTTGCCCCTAATCGGCCCTTAGGGTCAAAAA
  GTCCCTTGGGGCCCGAATTCCACCGGGGGGCCCCCTCTAAAAGGGGGGCCCTGGGCCCCT
  TTTCTTGGAGACCAGATGTTCCATTTGACCCTCAGAACCCTCTTTTGCCCCAAATTTACG
  GGCCCCCCTCTATAGGCAGG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_020070
• Insert Size: 980 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_020070.2, NP_064455.1
• RefSeq Size: 901 bp
• RefSeq ORF: 642 bp
• Locus ID: 3543
• UniProt ID: P15814
• Cytogenetics: 22q11.23
• Domains: ig, IGc1
• Protein Families: Secreted Protein
• Protein Pathways: Primary immunodeficiency
• Gene Summary: The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. This gene encodes one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. This gene does not undergo rearrangement. Mutations in this gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).