Transaldolase 1 (TALDO1) (NM_006755) Human Untagged Clone

CAT#: SC111031

TALDO1 (untagged)-Human transaldolase 1 (TALDO1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: Transaldolase 1
• Synonyms: TAL; TAL-H; TALDOR; TALH
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC111031 sequence for NM_006755 edited (data generated by NextGen Sequencing)
  ATGTCGAGCTCACCCGTGAAGCGTCAGAGGATGGAGTCCGCGCTGGACCAGCTCAAGCAG
  TTCACCACCGTGGTGGCCGACACGGGCGACTTCCACGCCATCGACGAGTACAAGCCCCAG
  GATGCTACCACCAACCCGTCCCTGATCCTGGCCGCAGCACAGATGCCCGCTTACCAGGAG
  CTGGTGGAGGAGGCGATTGCCTATGGCCGGAAGCTGGGCGGGTCACAAGAGGACCAGATT
  AAAAATGCTATTGATAAACTTTTTGTGTTGTTTGGAGCAGAAATACTAAAGAAGATTCCG
  GGCCGAGTATCCACAGAAGTAGACGCAAGGCTCTCCTTTGATAAAGATGCGATGGTGGCC
  AGAGCCAGGCGGCTCATCGAGCTCTACAAGGAAGCTGGGATCAGCAAGGACCGAATTCTT
  ATAAAGCTGTCATCAACCTGGGAAGGAATTCAGGCTGGAAAGGAGCTCGAGGAGCAGCAC
  GGCATCCACTGCAACATGACGTTACTCTTCTCCTTCGCCCAGGCTGTGGCCTGTGCCGAG
  GCGGGTGTGACCCTCATCTCCCCATTTGTTGGGCGCATCCTTGATTGGCATGTGGCAAAC
  ACCGACAAGAAATCCTATGAGCCCCTGGAAGACCCTGGGGTAAAGAGTGTCACTAAAATC
  TACAACTACTACAAGAAGTTTAGCTACAAAACCATTGTCATGGGCGCCTCCTTCCGCAAC
  ACGGGCGAGATCAAAGCACTGGCCGGCTGTGACTTCCTCACCATCTCACCCAAGCTCCTG
  GGAGAGCTGCTGCAGGACAACGCCAAGCTGGTGCCTGTGCTCTCAGCCAAGGCGGCCCAA
  GCCAGTGACCTGGAAAAAATCCACCTGGATGAGAAGTCTTTCCGTTGGTTGCACAACGAG
  GACCAGATGGCTGTGGAGAAGCTCTCTGACGGGATCCGCAAGTTTGCCGCTGATGCAGTG
  AAGCTGGAGCGGATGCTGACAGAACGAATGTTCAATGCAGAGAATGGAAAGTAG
  
  Clone variation with respect to NM_006755.1
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006755 unedited
  GTTCAAATTTGTATACGACTCCTATAGGCGGCCGCGNAATTCGCACGAGGCCTCGGTCTT
  GCTATGTCGAGCTCACCCGTGAAGCGTCAGAGGATGGAGTCCGCGCTGGACCAGCTCAAG
  CAGTTCACCACCGTGGTGGCCGACACGGGCGACTTCCACGCCATCGACGAGTACAAGCCC
  CAGGATGCTACCACCAACCCGTCCCTGATCCTGGCCGCAGCACAGATGCCCGCTTACCAG
  GAGCTGGTGGAGGAGGCGATTGCCTATGGCCGGAAGCTGGGCGGGTCACAAGAGGACCAG
  ATTAAAAATGCTATTGATAAACTTTTTGTGTTGTTTGGAGCAGAAATACTAAAGAAGATT
  CCGGGCCGAGTATCCACAGAAGTAGACGCAAGGCTCTCCTTTGATAAAGATGCGATGGTG
  GCCAGAGCCAGGCGGCTCATCGAGCTCTACAAGGAAGCTGGGATCAGCAAGGACCGAATT
  CTTATAAAGCTGTCATCAACCTGGGAAGGAATTCAGGCTGGAAAGGAGCTCGAGGAGCAG
  CACGGCATCCACTGCAACATGACGTTACTCTTCTCCTTCGCCCAGGCTGTGGCCTGTGCC
  GAGGCGGGTGTGACCCTCATCTCCCCATTTGTTGGGCGCATCCTTGATTGGCATGTGGCA
  AACACCGACAAGAAATCCTATGAGCCCCCTGGAGACCCTGNGGTANAGAGTGTCACTAAA
  ATCTACAACTACTACAAGAAGTTTAGCTACAAAACCATTGTCATGGGCGCCTCCTTTCCG
  CACACGGGCGAGATCAAAGCACTGCCCGGCTGTGACTTCCTCACATCTCACCCAGCTCCT
  GGGAGAGCTGCTGCAAGACAACGCCAAGCTGTTGCCTGTGCTCTCAACCCAAGGCGGCCC
  AGCCAGTGACCCTGGAAA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_006755 unedited
  TCTGGAACGCGGCACGCAATCTAGTATCGAGTTTTTTTTTTTTTTTTTTGAAACAGCACA
  GGAAAGTGACTGCTTTATGTATTAAGCAAAATTTTACATAAAATCAGAAATCTATGATCT
  GTCCCTGCTCCAATTTGTAAAAAACGCAAGATTCATCAGAAGCCACGTGCAGTCAGATCC
  CAGCTGGCCGGCGGTGCAGATCTGGAGTCCAGCCTCAGGGATGCGCTACTTTCCATTCTC
  TGCATTGAACATTCGTTCTGTCAGCATCCGCTCCAGCTTCACTGCATCAGCGGCAAACTT
  GCGGATCCCGTCAGAGAGCTTCTCCACAGCCATCTGGTCCTCGTTGTGCAACCAACGGAA
  AGACTTCTCATCCAGGTGGATTTTTTCCAGGTCACTGGCTTGGGCCGCCTTGGCTGAGAG
  CACAGGCACCAGCTTGGCGTTGTCCTGCAGCAGCTCTCCCAGGAGCTTGGGTGAGATGGT
  GAGGAAGTCACAGCCGGCCAGTGCTTTGATCTCGCCCGTGTTGCGGAAAGAGGCGCCCAT
  GACAATGGTTTTGTAGCTAAACTTCTTGTAGTAGTTGTAGATTTTATTGACACTCTTTAC
  CCCAGGGTCTTCCAGGGGCTCATATGATTTCTTGTCGGTGTTGCCACATGCCAATCAAGG
  ATGCGCCCCACATATGGGGAGATGATGTTCACACCCGCCTCGGCACATGCCACAGCCTGG
  GCGAAGGAGATAAGTACCGTCTGTTGCAATGGATGCCGGGCTGCTCCTCGAGCTTCTTTT
  CAGCCTGAATTCCTTCCCAGGTGGATGACAGCTTTATTAAGAATTTGGGTCCTTGCTTGA
  TCCCAGCCTCCCTGGTANAAACTCGATGAANCCGCCTTGCTTCTTGGCCACATCGGAATT
  TTTATTAAAGGAGAGCCTTGGGTTTAACTCTTGGGGAACTCTGGCCCGAATTTTCTCTTA
  TTTTTCTGTCCCAACACCACAAAAGTTTTTAATTGCATTCTTTATCG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_006755
• Insert Size: 1270 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_006755.1, NP_006746.1
• RefSeq Size: 1319 bp
• RefSeq ORF: 1014 bp
• Locus ID: 6888
• UniProt ID: P37837
• Cytogenetics: 11p15.5
• Domains: Transaldolase
• Protein Families: Druggable Genome
• Protein Pathways: Metabolic pathways, Pentose phosphate pathway
• Gene Summary: Transaldolase 1 is a key enzyme of the nonoxidative pentose phosphate pathway providing ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. This pathway can also maintain glutathione at a reduced state and thus protect sulfhydryl groups and cellular integrity from oxygen radicals. The functional gene of transaldolase 1 is located on chromosome 11 and a pseudogene is identified on chromosome 1 but there are conflicting map locations. The second and third exon of this gene were developed by insertion of a retrotransposable element. This gene is thought to be involved in multiple sclerosis. [provided by RefSeq, Jul 2008]