RAB23 (NM_016277) Human Untagged Clone

CAT#: SC110461

RAB23 (untagged)-Human RAB23, member RAS oncogene family (RAB23), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RAB23
• Synonyms: HSPC137
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_016277 edited
  GAATTCGGCACGAGGCCGGAGTGGGCAGGGGTATCGAGGGCAGGGGCCTCCCGGCCCGGC
  TCCCCCATCCCCCGGTTCGGACCGCCGAGCGCCGGCTCTCCCCTCCCTGAGCACCGATCC
  CAAGTTCCAGCTAGAGAAGGTGGGCGGCAGCGCCAGCCCGGCGCCCCCTCCCAGCTCCCA
  GCGATTTGAGAGGGAAGATCTGATCTCCTAGAATTAGAGTTGGTACAGAAACCATTTCAG
  CTCCAAAAATGTTGGAGGAAGATATGGAAGTCGCCATAAAGATGGTGGTTGTAGGGAATG
  GAGCAGTTGGAAAATCAAGTATGATTCAGCGATATTGCAAAGGCATTTTTACAAAAGACT
  ACAAGAAAACCATTGGAGTTGATTTTTTGGAGCGACAAATTCAAGTTAATGATGAAGATG
  TCAGACTAATGTTATGGGACACTGCAGGTCAGGAGGAATTTGATGCAATTACAAAGGCCT
  ACTATCGAGGAGCCCAGGCTTGTGTGCTCGTGTTCTCTACCACAGATAGGGAATCTTTTG
  AAGCAGTTTCCAGTTGGAGAGAGAAAGTAGTAGCCGAAGTGGGAGATATACCAACTGTAC
  TTGTGCAAAACAAGATTGATCTTCTGGATGATTCTTGTATAAAGAATGAGGAAGCTGAGG
  CACTGGCAAAAAGGTTAAAGTTAAGATTCTACAGAACATCAGTGAAAGAAGATCTAAATG
  TGAATGAAGTTTTTAAGTATTTGGCTGAAAAATACCTTCAGAAACTCAAACAACAAATAG
  CTGAGGATCCAGAACTAACGCATTCAAGTAGTAACAAGATTGGTGTCTTTAATACATCTG
  GTGGAAGTCACTCCGGTCAGAATTCAGGTACCCTCAATGGTGGAGATGTCATCAATCTTA
  GACCCAACAAACAAAGGACCAAGAAAAACAGAAATCCTTTTAGCAGCTGTAGCATACCCT
  AAGATGTTTTGGGAGGAAAACAATTGAATTACATTGTGCAATGCATTAAGAAACCCATCC
  AGCTGTCATGGTATGTTACAAGGTTTTCAGCAGACTTTGCTCCTAATGGCTCTCTGAAAG
  TGACAGACTTAAATATTGCTCTGCAGTGCTTTTCAGAATGTAGAGTGAGACCTCTGGTGG
  AAAAATTATTGCCCTGTGGACTCCTTTAATTTTTTTTACATTAGACGAAGCTTCTCCTGT
  TTGTAAAGGAATGCTATAAGAAATTTCAAACACAGGTTTTGCGGAATTTTAAATGCTGGA
  AAACATAAATGAAATGCCTAAATATATTGTTACAGATTTTAATACTGTGGATCAAGGAAA
  GATAGCAAGCATTCTTTTCCTGAAATTGGTCATGTAGCTTTTCTGCGAAATAGTATTCAA
  TCTGAATACTTTCACAAAATAATACTGAAAGGTAAACCCTAAATCTTGCCAGACTGCATT
  AGTATTTTGGCATTGAAACTTGTGCAATATCTGTGTAATGTAGAATGTGGGGTGTGCATG
  CAGATGTCTGGTACTGGAGTAAGCTGAAGGTATGTGCAGTATTTAAGAAAATGTACATTC
  TAATTAATTCACTTATAAAACCATTTACATATTGTGTATATGTTTTTATTTTCAAATGAT
  AAACTCTAGACATATATTTTGCAAAATGAGCTTGGGTTTAAAAAGTGCTTTGTGCCAAAA
  ATATCATACCTAATTTTTATAGTGCTTTACTATCAGAATTTATATTGTTTATTATATCTT
  TTAAAAGCAGTAAGCAGTTTTCATCTGACAGCGTAGATAAAAGAGGAGTATAGGAATTTG
  AATGCTAGAGCATCTCCCAGGTGAGCCTTATTGCAGATCTTTTTGATATAGTCACCCATA
  AGCATGGTGAGCTCCTGCTCTCATAAGGTCAGCCAAAGCCCCTTAAGAAGGTACACAGCA
  CATCTGCAGTCATTCAGGAGGTCCTGTGAAGTGTGGTGATGCATCTAACACCTTTTGCTG
  CTCACTGAGAACCCAGCTTTGAACTTACAAGATTACACTAACCATTTTTAAAGTGCACAA
  AAATATTATTATTAGTCTTAACTAAAATTACATATTTTATAATGCCCTGCAACTCTAAAC
  CATCCTTTTGTTTACACATTTTTGTATGGTATTTTAAGATTATCAATCACTTCAACATTT
  CTATAACCTTGTTTGTATAGCACTTTCTCAAGAGCTGTCAGTCCCACATACAGAATCATT
  TCTTTTACAAAATGATTTAATATGTAATCATGTGTCAGGACATAAATTTTGTCGCTTGGG
  ACAGTAGCTTTCCAGCTAAGATAATTGCGTGAACTCTGTTAAAACTGATTATCACTCATC
  AATGGCTTTATTTTTAACCTATAAATAACCCCTTTCAATATACCTGGTTTTTACAGCATT
  GCAAAATCTGTAAAAATAACTTTTATTGGAAAATGTCATGAAGTCATTTTTCATTATTTG
  TACTAAACAATGTTTTATGTACTCCTTTTGTGTTTTATCTTTTGTTTTTCCATCTGTACT
  CCCCTCATCCTCCTAATGTTGAGAAAATCAAATTTCCTGGGTGTGTCCTTGTTAAGTGAT
  CAAAAGTAAATGTTCTCTTTGCCATTTTAGATGGAAAAATAAAAAAAATTAAAAAGTAAA
  AAAAAAAAAAAAAAACTCGAC
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_016277 unedited
  GCATTTTGTAATACGAACTCACTATAGGGCGGCCGCGAATCGGCACGAGGGCCGGATGGG
  CAGGGGTATCGAGGGCAGGGGCCTCCCGGCCCGGCTCCCCCATCCCCCGGTTCGGACCGC
  CGAGCGCCGGCTCTCCCCTCCCTGAGCACCGATCCCAAGTTCCAGCTAGAGAAGGTGGGC
  GGCAGCGCCAGCCCGGCGCCCCCTCCCAGCTCCCAGCGATTTGAGAGGGAAGATCTGATC
  TCCTAGAATTAGAGTTGGTACAGAAACCATTTCAGCTCCAAAAATGTTGGAGGAAGATAT
  GGAAGTCGCCATAAAGATGGTGGTTGTAGGGAATGGAGCAGTTGGAAAATCAAGTATGAT
  TCAGCGATATTGCAAAGGCATTTTTACAAAAGACTACAAGAAAACCATTGGAGTTGATTT
  TTTGGAGCGACAAATTCAAGTTAATGATGAAGATGTCAGACTAATGTTATGGGACACTGC
  AGGTCAGGAGGAATTTGATGCAATTACAAAGGCCTACTATCGAGGAGCCCAGGCTTGTGT
  GCTCGTGTTCTCTACCACAGATAGGGAATCTTTTGAAGCAGTTTCCAGTTGGAGAGAGAA
  AGTAGTAGCCGAAGTGGGAGATATACCAACTGTACTTGTGCAAAACAAGATTGATCTTCT
  GGATGATTCTTGTATAAAGAATGAGGAAGCTGANGCACTGGNCAAAGGTTAAAAGTAAGA
  TTCTACAGAACATCAGTGAAAGAAGAATCTAATGTGAATGAAAGTTTTAAGTATTTGGCT
  GANNAATACCTTCAGAAACTCANACAACANATAGCTNGAGGATCCCAGAACTAACGCATT
  NCAGTAGTAACCAGATTGGNTGTCTTTAATACATCTGGTGGGAGTCACTCCGGTCAGAAT
  TCANGGTACCTCATGGTTGGAGATGTCATCAATCTT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_016277 unedited
  CCGCAATCTAAAGTCGAGTTTTTTTTTTTTTTTTTTACTTTTTAATTTTTTTTATTTTTC
  CATCTAAAATGGCAAAGAGAACATTTACTTTTGATCACTTAACAAGGACACACCCAGGAA
  ATTTGATTTTCTCAACATTAGGAGGATGAGGGGAGTACAGATGGAAAAACAAAAGATAAA
  ACACAAAAGGAGTACATAAAACATTGTTTAGTACAAATAATGAAAAATGACTTCATGACA
  TTTTCCAATAAAAGTTATTTTTACAGATTTTGCAATGCTGTAAAAACCAGGTATATTGAA
  AGGGGTTATTTATAGGTTAAAAATAAAGCCATTGATGAGTGATAATCAGTTTTAACAGAG
  TTCACGCAATTATCTTAGCTGGAAAGCTACTGTCCCAAGCGACAAAATTTATGTCCTGAC
  ACATGATTACATATTAAATCATTTTGTAAAAGAAATGATTCTGTATGTGGGACTGACAGC
  TCTTGAGAAAGTGCTATACAAACAAGGTTATAGAAATGTTGAAGTGATTGATAATCTTAA
  AATACCATACAAAAATGTGTAAACAAAAGGATGGTTTAGAGTTGCAGGGCATTATAAAAT
  ATGTAATTTTAGTTAAGACTAATAATAATATTTTTGTGCACTTTAAAAATGGTTAGTGTA
  ATCTTGTAAGTTCAAAGCTGGGTTCTCAGTGAGCAGCAAAAGGTGTTAGATGCATCACCA
  CACTTCACAGGACCTCCTGAATGACTGCAGATGTGCTGTGTACCTTCTTAAAGGGGCTTT
  GCTGACCTTATGAGAAGCAGAGCTCACCATGCTTATGGGTGACTATATCAAAAAGATCTG
  CNATAAGGCTCACCTGGGAGATGCTCTAGCATCCAAATCCTATACTCCTCTTTATCTACG
  CTGTCAGATGAAAACTGCTTACTGCTTTAANAGATTTATAAACAATATAATCCTGATAGT
  AAGCCTTTAAATTAGGTTGATATTTTGGGCCAAGACTTTTAAACCAGCTT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_016277
• Insert Size: 2630 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_016277.3, NP_057361.3
• RefSeq Size: 3037 bp
• RefSeq ORF: 714 bp
• Locus ID: 51715
• UniProt ID: Q9ULC3
• Cytogenetics: 6p12.1-p11.2
• Domains: ras, RAN, RAS, RHO, RAB
• Protein Families: Druggable Genome
• Protein Pathways: Hedgehog signaling pathway
• Gene Summary: This gene encodes a small GTPase of the Ras superfamily. Rab proteins are involved in the regulation of diverse cellular functions associated with intracellular membrane trafficking, including autophagy and immune response to bacterial infection. The encoded protein may play a role in central nervous system development by antagonizing sonic hedgehog signaling. Disruption of this gene has been implicated in Carpenter syndrome as well as cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
  Transcript Variant: This variant (1) represents the longest transcript. Variants 1-5 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.