RAC1 (NM_018890) Human Untagged Clone

CAT#: SC109694

RAC1 (untagged)-Human ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) (RAC1), transcript variant Rac1b

USD 402.00

In Stock

    • 10 ug

Product images


Product Data
Product Name RAC1 (NM_018890) Human Untagged Clone
Symbol RAC1
Synonyms MIG5; p21-Rac1; Rac-1; TC-25
Vector pCMV6-XL5
Sequence Data
Fully Sequenced ORF
>OriGene sequence for NM_018890 edited
Tag Tag Free
ACCN NM_018890
ORF Size 636 bp
Insert Size 900
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation The ORF of this clone has been fully sequenced and found to be a perfect match to NM_018890.2.
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reference Data
RefSeq NM_018890.2, NP_061485
RefSeq Size 2412
RefSeq ORF 636
Locus ID 5879
Cytogenetics 7p22.1
Domains ras
Protein Families Druggable Genome
Protein Pathways MAPK signaling pathway, Chemokine signaling pathway, Wnt signaling pathway, Axon guidance, VEGF signaling pathway, Focal adhesion, Adherens junction, Toll-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Leukocyte transendothelial migration, Neurotrophin signaling pathway, Regulation of actin cytoskeleton, Amyotrophic lateral sclerosis (ALS), Epithelial cell signaling in Helicobacter pylori infection, Pathways in cancer, Colorectal cancer, Renal cell carcinoma, Pancreatic cancer, Viral myocarditis
Gene Summary Isoform B has an accelerated GEF-independent GDP/GTP exchange and an impaired GTP hydrolysis, which is restored partially by GTPase-activating proteins. It is able to bind to the GTPase-binding domain of PAK but not full-length PAK in a GTP-dependent manner, suggesting that the insertion does not completely abolish effector interaction. [UniProtKB/Swiss-Prot Function]
Transcript Variant: This variant (Rac1b) includes the alternatively spliced 57 bp region (exon 3b) that is missing in transcript variant Rac1.
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.