DLX4 (NM_138281) Human Untagged Clone

CAT#: SC109157

DLX4 (untagged)-Human distal-less homeobox 4 (DLX4), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: DLX4
• Synonyms: BP1; DLX7; DLX8; DLX9; OFC15
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_138281, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGACCTCTTTGCCCTGCCCCCTCCCCGGCCGGGACGCCTCCAAAGCTGTCTTCCCAGACCTCGCCCCTG
  TCCCGTCGGTAGCGGCTGCCTACCCGCTTGGCTTGTCCCCTACAACCGCAGCCTCCCCCAATTTGTCCTA
  CTCCAGGCCGTATGGCCACCTCCTGTCTTACCCCTACACCGAGCCAGCGAACCCCGGAGACTCCTACCTG
  TCCTGCCAGCAACCCGCGGCGCTCTCTCAGCCCCTCTGCGGACCTGCAGAGCACCCTCAGGAACTCGAGG
  CAGACTCGGAGAAGCCGCGGCTGTCCCCGGAACCCTCCGAGCGGCGCCCTCAGGCCCCCGCCAAAAAGCT
  CCGCAAGCCGAGGACCATCTACTCCAGCCTGCAGCTGCAGCACCTAAACCAGCGTTTCCAGCACACGCAG
  TACCTGGCGCTGCCCGAGAGGGCCCAGCTGGCAGCGCAGCTCGGCCTCACCCAGACCCAGGTAAAGATCT
  GGTTTCAGAACAAACGCTCCAAGTATAAGAAGCTCCTGAAGCAGAATTCTGGGGGGCAGGAAGGGGACTT
  CCCTGGGAGGACCTTCTCTGTGTCTCCCTGCTCCCCACCCCTCCCCTCCCTCTGGGATCTACCCAAGGCA
  GGGACCCTGCCCACCAGTGGCTATGGCAACAGCTTTGGAGCCTGGTATCAGCATCACTCCTCAGATGTCC
  TGGCTTCGCCTCAGATGATGTGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_138281 unedited
  AAGGTTCAAATTTGTATACGACTCACTATAGGCGGCCGCGATTCGGCACCANANCACTTT
  CTCCGGGATCTTAAGTGTGGGGGCTGCTGGCTGGGGGGCCCGTCCGGCCCAACGCCGGAG
  GCTTGGAAAAGAGAGTTGGCAGCGGGAGCGGACTACGTGCCGGGCCATGGCCCTTCTGCC
  CGGGCCCTGGCCACAATGACCTCTTTGCCCTGCCCCCTCCCCGGCCGGGACGCCTCCAAA
  GCTGTCTTCCCAGACCTCGCCCCTGTCCCGTCGGTAGCGGCTGCCTACCCGCTTGGCTTG
  TCCCCTACAACCGCAGCCTCCCCCAATTTGTCCTACTCCAGGCCGTATGGCCACCTCCTG
  TCTTACCCCTACACCGAGCCAGCGAACCCCGGAGACTCCTACCTGTCCTGCCAGCAACCC
  GCGGCGCTCTCTCAGCCCCTCTGCGGACCTGCAGAGCACCCTCAGGAACTCGAGGCAGCA
  TTCTAGGGCTGGGCTGTCCCGCGGCCGAGATTCCTGGAGAGCTAGGCGGGCCAGAGCTGA
  CCAGATCCCCCGCGGCGGCACCGCAGCGCGATCCAGGAGTGGCCCCGCCGGGCTACGCTG
  CGCGCTCTTGGAACCCGGGTCACCTTCCCTGCCGCCGGAACCGCTCTGTGCGCGCTGCCC
  AACGAAGGAAGGGGCTGCCCCACGCAGACCCGGCTTCTGGGGGTCCCTGNGAACCCAGGC
  GGCCACGGTGTGGCGGGGGAGACATGGTCACTTTTCCTGCAGGGTGCGCCTGNAGCAGAG
  GGCAGCCCGTTACAGTAGGCGAGGCCAGGGCAAACCCGGGGTCACTATCAGCGCTGCGAG
  ACTGGTATTCAGGGTCTCTCAGCCGGCCTCTCACCCACCCCGCTGGCCGCAGCCGGAAGC
  TTGCACNCA
  
  3' Read Nucleotide Sequence

  >OriGene 3' genomic read for NM_138281 unedited
  CGCTTTGGAACCGCGGCCGCATNCTAGNGATCGGTTTTTTTTTTTTTTTTTTTAGGAGGA
  AAGCATAAATTACCCATAGGTCCACAAATTCCACATTTCTCTGCATCTCTTCTACCTCCC
  AGTATGGTAAGTAGGTAAATCAGTTATGGGGGTAACGGGCTGACCTCCAAGGAAAAATCG
  CTGGGTGGGTGGGAGCTGATGGTGGTCCACTTCTGCTTTTGCTCACAAATGGGTTGTGCA
  AGGCCAAAGGCATACAAAGAAAAAAAAATACTCAATGTTTCTTGCTGATTTTGCACCCAG
  GCTGTAGTGGCGATTCAGTCCTTTTCAAGAAAGCAGGGAGAGGAGAAAGGGAGAGAGGGA
  AGAAGGAGTGGNGGGAGTGGCAAGACCAAGGGTTCTGGGGACAGTCTCAACTCCAGCCAA
  TGGCTCTCTCTCCAGAGTCTTTGTCCAGCTGGAGTGAAGGTGTCCAGTCCATGGTAGTGG
  TGGGGACAATGATTATATAAGGCTGAGGTCCTTGATTTAGCTGTTAGGGTTAGGGGTACA
  GGCTCTGCTCCATTCCTTTTTCTCCTCTAACTGCTTGTCCTCCAGAGAAAACCCATCTGG
  AGCTGGTTTCCTCCCAGCCCAGAAGGGGTGCAGGTGGACTGCCTGGGTCCTGGGCTTTGC
  AGGAAGGCTGTGGGCCTGACCCGCCCTTCCCCAGATTCACATCATCTGAGGCGAAGCCAG
  GACATCTGGAGAGTGATGCTGATACCAGGCTCCAAAGCTGTTGCCATAGCCACTGGTGGG
  CAGGGTCCCTGCCTTGGGTAGATCCCANAAGGAGGGAAGGGGTTGGATTTTTT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_138281
• Insert Size: 2750 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_138281.1, NP_612138.1
• RefSeq Size: 1659 bp
• RefSeq ORF: 723 bp
• Locus ID: 1748
• UniProt ID: Q92988
• Cytogenetics: 17q21.33
• Domains: homeobox
• Protein Families: Transcription Factors
• Gene Summary: Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. The DLX proteins are postulated to play a role in forebrain and craniofacial development. Three transcript variants have been described for this gene, however, the full length nature of one variant has not been described. Studies of the two splice variants revealed that one encoded isoform functions as a repressor of the beta-globin gene while the other isoform lacks that function. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) encodes the longer isoform (a, also known as BP1), which functions as a repressor of the beta-globin gene.