CDC42(CDC42) (NM_044472) Human Untagged Clone

CAT#: SC109056

CDC42 (untagged)-Human cell division cycle 42 (GTP binding protein, 25kDa) (CDC42), transcript variant 2

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Size
    • 10 ug

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Specifications

Product Data
Product Name CDC42(CDC42) (NM_044472) Human Untagged Clone
Symbol CDC42
Synonyms CDC42Hs; G25K
Vector pCMV6-XL5
Sequence Data
Fully Sequenced ORF
>OriGene sequence for NM_044472 edited
GAATTCGGCACGAGGCTGAGGTCATCATCAGATTTGAAATATTTAAAGTGGATACAAAAC
TATTTCAGCAATGCAGACAATTAAGTGTGTTGTTGTGGGCGATGGTGCTGTTGGTAAAAC
ATGTCTCCTGATATCCTACACAACAAACAAATTTCCATCGGAATATGTACCGACTGTTTT
TGACAACTATGCAGTCACAGTTATGATTGGTGGAGAACCATATACTCTTGGACTTTTTGA
TACTGCAGGGCAAGAGGATTATGACAGATTACGACCGCTGAGTTATCCACAAACAGATGT
ATTTCTAGTCTGTTTTTCAGTGGTCTCTCCATCTTCATTTGAAAACGTGAAAGAAAAGTG
GGTGCCTGAGATAACTCACCACTGTCCAAAGACTCCTTTCTTGCTTGTTGGGACTCAAAT
TGATCTCAGAGATGACCCCTCTACTATTGAGAAACTTGCCAAGAACAAACAGAAGCCTAT
CACTCCAGAGACTGCTGAAAAGCTGGCCCGTGACCTGAAGGCTGTCAAGTATGTGGAGTG
TTCTGCACTTACACAGAGAGGTCTGAAGAATGTGTTTGATGAGGCTATCCTAGCTGCCCT
CGAGCCTCCGGAAACTCAACCCAAAAGGAAGTGCTGTATATTCTAAACTGTTTTCTCCTT
CCCTTCTTTGCTGCTGCTTCCTGTCCCACTACTGTAGAAAGATCGTTTAAAAACAAAGGA
ATAAAACCATCCTGTTTGAAAGCCTCTGCGTCTTTTTACTCACCACCTTAXXXXXXXXXX
XXXXCTCGAC
5' Read Nucleotide Sequence
>OriGene 5' read for NM_044472 unedited
AGTCAAATTTGTATACGACTCATATAGGGCGGCCGCGAATTCGCACGAGGCTGAGGTCAT
CATCAGATTTGAAATATTTAAAGTGGATACAAAACTATTTCAGCAATGCAGACAATTAAG
TGTGTTGTTGTGGGCGATGGTGCTGTTGGTAAAACATGTCTCCTGATATCCTACACAACA
AACAAATTTCCATCGGAATATGTACCGACTGTTTTTGACAACTATGCAGTCACAGTTATG
ATTGGTGGAGAACCATATACTCTTGGACTTTTTGATACTGCAGGGCAAGAGGATTATGAC
AGATTACGACCGCTGAGTTATCCACAAACAGATGTATTTCTAGTCTGTTTTTCAGTGGTC
TCTCCATCTTCATTTGAAAACGTGAAAGANAAGTGGGTGCCTGAGATAACTCACCACTGT
CCAAAGACTCCTTTCTTGCTTGTTGGGACTCAAATTGATCTCAGAGATGACCCCTCTACT
ATTGAGAAACTTGCCAAGAACAAACAGAAGCCTATCACTCCAGAGACTGCTGAAAAGCTG
GCCCGTGACCTGAAGGCTGTCAAGTATGTGGAGTGTTCTGCACTTACACAGAGAGGTCTG
AAGAATGTGTTTGATGAGGCTATCCTAGCTGCCCTCGAGCCCTCGGAACTCNACCCAAAA
GAAGTGCTGTATATTCTAAACTGGTTTCTCCTTCCCTTNCTTGCTGCTGCTTCCTGTCCC
ACTACTGTAGAAAGATCGTTTAANAACAAAGGAATAAAACATCCTGTTTGAAAGCCTCTG
CGTCCTTTTACTCACCACCTAGAGCACCTCTGTATTAGTTTTTGATCAAGAATGCATTAT
CATATAAATTTTTTGGGATCAGTAGCCAAGTGGGACTTGTTTTAAACGTTCTGCTGCCTG
GATTGGCCTGAAGCTCAAAGCTTTTTGGTTGGAATACTATTGGCAAAGG
3' Read Nucleotide Sequence
>OriGene 3' read for NM_044472 unedited
GGCACGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTAACAAACGGGTGTATATTTTTAATTTCAAAATTTGAAGGTAACCACAATTGTTT
TTTTCCCTCACAATAAAATCAAAAGCCGGAAAATATAAAGGGGGCAGCTTTACATCTCAA
CATTAACAAACTGTAAGTCAACTGTTTAAATGGATGTTATTCTTAAAAAATAATGTAACA
AATGAACTCATAAAGCAGTAGCAAATACCTCAATTTCTTCCCCACCCCAAACTGACAAAT
ACTCCACTACAGCACAAACAGCCAAAGCAACAGCAACACAAAGTTTCACCGCCCAAAGGA
AAACCAGAAAAGAATCCTCCCTTCCCCATTACACTTTACTAGGGCACCCCTTTTCCATAA
GGGTTGGCATGCAATTACAATTAACAATTGATCATAAAAGTAAAAGGATGTTTGGGTTAC
TTTCTCCCTCTAAAACTAAAATCTAAAAGTGTTAAAACTCTTGTTATTTTCTCCAAAAGG
ACATTCTTAAAGCCAAACCAAGTTCCCTTTTGCAATAGTAATCCAAACCAAAAAGCTCTG
AGCATCAGGCAACTCAAGCAGCAGAACGTTAAAACAAGTCCAACTTGACTCCTGATCACA
AAAAATTTATTTGATATTGCCTTCTGGATCAAAACTATACAGAGGTTGCTCTAAGGGGGG
AGTAAAAAACACGAAGCTTTAAACAGGAGGTTTTATTCCTTGTTTTAAAAATCTTTTTCA
GTTGTGGGCANGAACCCCNCCAAAAAAAGGAAGAAAAAACAGTTAAAATTTCCCCCCTTC
CTTTAGGTGTGATTTCCCGAGGCCCAGGCAACTAGATAACCTATAAAACACTTTTAAACC
TCTGGGAAGGGAAAACCCCCATCTTGAAGCCTTAGGCACGGGCACTTTTAAAT
Restriction Sites NotI-NotI     
Tag Tag Free
ACCN NM_044472
ORF Size 576 bp
Insert Size 1460
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reference Data
RefSeq NM_044472.1, NP_426359
RefSeq Size 1135
Locus ID 998
Cytogenetics 1p36.12
Domains ras, RAS, RHO, RAB
Protein Families Druggable Genome
Protein Pathways MAPK signaling pathway, Chemokine signaling pathway, Endocytosis, Axon guidance, VEGF signaling pathway, Focal adhesion, Adherens junction, Tight junction, T cell receptor signaling pathway, Fc gamma R-mediated phagocytosis, Leukocyte transendothelial migration, Neurotrophin signaling pathway, Regulation of actin cytoskeleton, GnRH signaling pathway, Epithelial cell signaling in Helicobacter pylori infection, Pathogenic Escherichia coli infection, Pathways in cancer, Renal cell carcinoma, Pancreatic cancer
Gene Summary The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3, 4, 5, 7, 8 and 20. [provided by RefSeq, Apr 2013]
Transcript Variant: This variant (2) differs from variant 1 at the 3' region including a small part of the coding region and the entire 3' UTR. This variant encodes isoform 2 which has the same aa length but different C-terminus from isoform 1.
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.