Caspase-7(CASP7) (NM_033340) Human Untagged Clone

CAT#: SC109027

CASP7 (untagged)-Human caspase 7, apoptosis-related cysteine peptidase (CASP7), transcript variant beta

USD 402


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Size
    • 10 ug

Product images

Specifications

Product Data
Product Name Caspase-7(CASP7) (NM_033340) Human Untagged Clone
Symbol CASP7
Synonyms CASP-7; CMH-1; ICE-LAP3; LICE2; MCH3
Vector pCMV6-XL5
Sequence Data
Fully Sequenced ORF
>NCBI ORF sequence for NM_033340, the custom clone sequence may differ by one or more nucleotides


ATGGCAGATGATCAGGGCTGTATTGAAGAGCAGGGGGTTGAGGATTCAGCAAATGAAGATTCAGTGGATG
CTAAGCCAGACCGGTCCTCGTTTGTACCGTCCCTCTTCAGTAAGAAGAAGAAAAATGTCACCATGCGATC
CATCAAGACCACCCGGGACCGAGTGCCTACATATCAGTACAACATGAATTTTGAAAAGCTGGGCAAATGC
ATCATAATAAACAACAAGAACTTTGATAAAGTGACAGGTATGGGCGTTCGAAACGGAACAGACAAAGATG
CCGAGGCGCTCTTCAAGTGCTTCCGAAGCCTGGGTTTTGACGTGATTGTCTATAATGACTGCTCTTGTGC
CAAGATGCAAGATCTGCTTAAAAAAGCTTCTGAAGAGGACCATACAAATGCCGCCTGCTTCGCCTGCATC
CTCTTAAGCCATGGAGAAGAAAATATGGAATCTTGCTCTGTCACCCAGGCTGGAGTGCAGCGGCGTGATC
TCGGAAGACTGCAACCTCCACCTCCCAGGCTTGCCGAGGGACCGAGCTTGATGATGGCATCCAGGCCGAC
TCGGGGCCCATCAATGACACAGATGCTAATCCTCGATACAAGATCCCAGTGGAAGCTGACTTCCTCTTCG
CCTATTCCACGGTTCCAGGCTATTACTCGTGGAGGAGCCCAGGAAGAGGCTCCTGGTTTGTGCAAGCCCT
CTGCTCCATCCTGGAGGAGCACGGAAAAGACCTGGAAATCATGCAGATCCTCACCAGGGTGA


5' Read Nucleotide Sequence
>OriGene 5' read for NM_033340 unedited
GGATTTTGTAATACGACTCACTATAGGGNNCGGCCGCGAAATTCGGCACGAGGGCAAGCT
GGGCTGCTGGGTGGGTACTTCCTTCAAAGCTGAGGGAGCGTCCTACGCCCACGCGCGCAG
GAGGGCGCCCCCCGCAAAGCAACGTCTAGGAGACCACAGTGGATGCCACAGCGGGCCCGA
AGCGGATCAGCCTTGTGGGATGGCAGATGAGCAGGGCTGTATTGAAGAGCAGGGGGTTGA
GGATTCAGCAAATGAAGATTCAGTGGATGCTAAGCCAGACCGGTCCTCGTTTGTACCGTC
CCTCTTCAGTAAGAAGAAGAAAAATGTCACCATGCGATCCATCAAGACCACCCGGGACCG
AGTGCCTACATATCAGTACAACATGAATTTTGAAAAGCTGGGCAAATGCATCATAATAAA
CAACAAGAACTTTGATAAAGTGACAGGTATGGGCGTTCGAAACGGAACAGACAAAGATGC
CGAGGCGCTCTTCAAGTGCTTCCGAAGCCTGGGTTTTGACGTGATTGTCTATAATGACTG
CTCTTGTGCCAAGATGCAAGATCTGCTTAAAAAAGCTTCTGAAGAGGACCATACAAATGC
CGCCTGCTTCGCCTGCATCCTCTTAAGCCATGGAGAAGAAAATGTAATTTATGGGAAAGA
TGGTGTCACACCAATAAAGGATTTGACAGCCCACTTTANGGGGGATAGATGCAAAACCCT
TTTAGAGAAACCCAAACTCTTCTTCATTCANGCTTGCCGNAGGACCGAGCTTGATGATGG
CATCCAGGCCGACTCGGGGCCATCATGACACGATGCTAATCCTCGATACAAGATCCAGTG
GAAGCTGACTTNCTCNTCGNCTATTNCACGGNNTCCAGCTATTACTCGTGGNAGAGCCCN
AGAAAGAGCTNCTGGTTNGTGCAAGCCTCTGCTTCTNCTGNAGAGCCNGNAAAGACTGNA
ATATGCAGACCTNACCAGGTGATGAACAGAGTGCAGCACTTTGAGCT
3' Read Nucleotide Sequence
>OriGene 3' read for NM_033340 unedited
GTCCATCTATGNNACCGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTAAACAACCCGTGTTTAATCAATAAATATGAACCTTTGTT
TTTTAACCCGTTACTATTAGGCAGAAAAAAACAGTCCTTTTTCAAGAATTCAAAAGATAA
CCCCCTCTTGAAAACAAAGTGCCAAAAATCTTTGCCATAAACTCTTCCTCACTTATAGAA
CTAAAAGTAACAGATTTTTACTCAAAATAAGGGTTGGAATAATCTAAAAAGTTCCAGATT
TTTTTTAAAGCTATAACAGATTTTGCACATAAAGCCAAAACAGATTGGTTTACACATACC
TAGACTATCTGACAACCCAATGAATAAATGATTGAATGGGTAAATTGGTGAGCCTTAGGG
ATTACTTATGTTCACATTATGGGCCAGGCTTACATCCATTTCTTGGTCTTCTCCTGCCTC
ACTGGCCCTTGCTCTTCCAAGGGCCTTGGGGAGGGGGCTTCCAAATAGGCCTGGGCAGTA
AGGGGCTGGTGGAAAATGTGAGGGCAGGATAGGTGAGACCAAGGGATTCTCTTATCTGGC
TCAACTCACTCCATCTCAGTCAGTGGTTTTGTTCTTGTCATGGCTCCATTTTCCACAATC
CATTGGGTGGTCCTAACTCCCACTAGGCAGCCCCCACCATGGTTCCAGCTCCTCTGGATG
ATCCCACTACTGGACACAGGAAACCAAACCTCTTCCCATTATCCTCATAGCCCTGGGGTG
TGGTAACAGCTTCTTGCTGGTTGGCCTCCCTTTATCATCTATGAAGTCAATTTCCTGTAT
TAAACTCCCTCTGGTGAAACCCCTAAATGGTTTCCTGTTTTCANACTGGATCCCTGATGA
TACATTTCAGAATCC
Restriction Sites NotI-NotI     
Tag Tag Free
ACCN NM_033340
ORF Size 762 bp
Insert Size 2500
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reference Data
RefSeq NM_033340.2, NP_203126
RefSeq Size 2433
RefSeq ORF 762
Locus ID 840
Cytogenetics 10q25.3
Domains Peptidase_C14
Protein Families Protease, Druggable Genome
Protein Pathways Apoptosis, Alzheimer's disease
Gene Summary This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012].
Transcript Variant: This variant (b, also known as beta) has multiple differences in the 5' UTR and coding region, and initiates translation at a downstream in-frame start codon, compared to variant d. The encoded isoform (beta) is shorter and has a distinct C-terminus, compared to isoform delta.
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.