UQCRH (NM_006004) Human Untagged Clone

CAT#: SC108564

UQCRH (untagged)-Human ubiquinol-cytochrome c reductase hinge protein (UQCRH), nuclear gene encoding mitochondrial protein

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: UQCRH
• Synonyms: QCR6; UQCR8
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC108564 sequence for NM_006004 edited (data generated by NextGen Sequencing)
  ATGGGACTGGAGGACGAGCAAAAGATGCTTACCGAATCCGGAGATCCTGAGGAGGAGGAA
  GAGGAAGAGGAGGAATTAGTGGATCCCCTAACAACAGTGAGAGAGCAATGCGAGCAGTTG
  GAGAAATGTGTAAAGGCCCGGGAGCGGCTAGAGCTCTGTGATGAGCGTGTATCCTCTCGA
  TCACATACAGAAGAGGATTGCACGGAGGAGCTCTTTGACTTCTTGCATGCGAGGGACCAT
  TGCGTGGCCCACAAACTCTTTAACAACTTGAAATAA
  
  Clone variation with respect to NM_006004.2
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006004 unedited
  GGTGCANAAATTTGTAATACGACTCACTATAGGGGCGGCCGCGATTCGGCACGAGGGGGT
  TAGGTGCCGCTGTTGCTGCTCGTGTTGAATCTAGAACCGTAGCCAGACATGGGACTGGAG
  GACGAGCAAAAGATGCTTACCGAATCCGGAGATCCTGAGGAGGAGGAAGAGGAAGAGGAG
  GAATTAGTGGATCCCCTAACAACAGTGAGAGAGCAATGCGAGCAGTTGGAGAAATGTGTA
  AAGGCCCGGGAGCGGCTAGAGCTCTGTGATGAGCGTGTATCCTCTCGATCACATACAGAA
  GAGGATTGCACGGAGGAGCTCTTTGACTTCTTGCATGCGAGGGACCATTGCGTGGCCCAC
  AAACTCTTTAACAACTTGAAATAAATGTGTGGACTTAATTCACCCCAGTCTTCATCATCT
  GGGCATCAGAATATTTCCTTATGGTTTTGGATGTACCATTTGTTTCTTATTTGTGTAACT
  GTAAGTTCACATGAACCTCATGGGTTTGGCTTAGGCTGGTAGCTTCTATGTAATTCGCAA
  TGATTCCATCTAAATAAAAGTTCTATGATCTGCAAAAAAAAAAAAAAAAAACTCGACTCT
  AGATTGCGGCCGCGGTCATAGCTGTTTCCTGAACAGATCCCGGGTGGCATCCCTGTGACC
  CCTCCCCAGTGCCTCTCCTGGCCCTGGAAGTTGGCACTCCAGTGCCCACCAGCCTTGTCC
  TATTAAAATTAAGTTGCATCATTTTGTCTGACTAGGTGTCCTTCTATATATTATGGGGTG
  GAGGAGGGTGCGTTGGCACCAGCGGCCACGTTGGAAAACACCTCGCAGGCCTGCGGGGCC
  TATTGGCAACCAGCCTGAATGCAGTGGCACAACCTTGGCTTCCTGTATCCCCCCCTTCTG
  GGTCCAAGCGATCTTCTGCTC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_006004 unedited
  TTCTCTGCCACCGCGGCCCGCAATCTANGATCGAGTTTTTTTTTTTTTTTTTTGCAGAAA
  TAGAACTTTTATTTAGATGGAATCATTGCGAATTACATAGAAGCTACCAGCCTAAGCCAA
  ACCCATGAGGTTCATGTGAACTTACAGTTACACAAATAAGAAACAAATGGTACATCCAAA
  ACCATAAGGAAATATTCTGATGCCCAGATGATGAAGACTGGGGTGAATTAAGTCCACACA
  TTTATTTCAAGTTGTTAAAGAGTTTGTGGGCCACGCAATGGTCCCTCGCATGCAAGAAGT
  CAAAGAGCTTCTCCGTGCAATCCTCTTTTGTATGTGATCGAGAGGATACACGCTCATCAC
  AGAGCTCTAGCCGCTCCCGGGCCCTTACACATTTCTTCAACTGCTCGCATTGCTCTCTCA
  CTGTTGTTAGGGGATCCACTAATCCCTCCTTTTCCTCTTCCTCCTCCTTAGGATTTCCGG
  ATTCCGCAAGCATCTTTTGCTCGCTCTCCAGTCCCATGTCTGGCCACGGTCCTATACTCA
  ACACGATCAGCAACAGTGGCACCTAATCCCCTCGTGCCGAATCTCCGGCCCGCCTATAGC
  GAGCCGCATTCATCAATTCTGACGGCTCACTAAACGAGCTCTGTTTATATAGACCTCCCA
  CCGCACACCCGTATCGCCCATTCTCGTCCACCGGCGTGGGGCTATCACCACATTCCGGCA
  AGCCCCGCCGCTTTTTGCCGCCTCAACACACCCTCATTGTCGCTCATGGGCTGTCCCATT
  GTAACCCCCCCTGAATTCACACCCTCTCCCGCCCCTTGCGCGATCGCCTAACCCTCTCCC
  CCCGTACATACCTTGCACACCCTTTTTATGTCCGCTCCTTTTAAGATTCTCTAGGCCTGC
  CCTGCCTAATCGCCGCGCATTTTTCCCCTCTTTGCCCCACCCGCCGCCC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_006004
• Insert Size: 550 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_006004.1, NP_005995.1
• RefSeq Size: 515 bp
• RefSeq ORF: 276 bp
• Locus ID: 7388
• UniProt ID: P07919
• Cytogenetics: 1p33
• Domains: UCR_hinge
• Protein Families: Druggable Genome
• Protein Pathways: Alzheimer's disease, Cardiac muscle contraction, Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease
• Gene Summary: This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1.[UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (1) encodes the longest isoform (1).