SCD5 (AL831891) Human Untagged Clone

CAT#: SC105787

(untagged)-Human mRNA, cDNA DKFZp547D048 (from clone DKFZp547D048)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SCD5
• Synonyms: ACOD4; FADS4; HSCD5; SCD2; SCD4
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for AL831891, the custom clone sequence may differ by one or more nucleotides
  
  
  GGGGAGAAAGCTTGACGTCACTGACCTGCTTGCTGATCCTGTGGTCCGGATCCAGAGAAAGTACTATAAG
  ATCTCCGTGGTGCTCATGTGCTTTGTGGTCCCCACGCTGGTGCCCTGGTACATCTGGGGAGAGAGTCTGT
  GGAATTCCTACTTCTTGGCCTCTATTCTCCGCTATACCATCTCACTCAACATCAGCTGGCTGGTCAACAG
  CGCCGCCCACATGTATGGAAACCGGCCCTATGACAAGCACATCAGCCCTCGGCAGAACCCACTCGTCGCT
  CTGGGTGCCATTGGTGAAGGCTTCCATAATTACCATCACACCTTTCCCTTTGACTACTCTGCGAGTGAAT
  TTGGCTTAAATTTTAACCCAACCACCTGGTTCATTGATTTCATGTGCTGGCTGGGGCTGGCCACTGACCG
  CAAACGGGCAACCAAGCCGATGATCGAGGCCCGGAAGGCCAGGACTGGAGACAGCAGTGCTTGAACTTGG
  AACAGCCATCCCACATGTCTGCCGTTGCAACCTCGGTTCATGGCTTTGGTTACAATAGCTCTCTTGTACA
  TTGGATCGTGGGAGGGGGCAGAGGGTGGGGAAGGAACGAATCAATGTGGTTTGGGAATGTTTTTGTTTAT
  CTCAAAATAATGTTGAAATACAATTATCAATGAAAAAACTTTTGTTTTTTTTTTTTGTTTGTTTTGTTTT
  TGAGACAGAGTCTCACTCTGTCACCCAGGCTGGAGTGCAGTGGCGCAGTCTCGGCTCACTGCAGCCTCCA
  CCTACCTGGTTCAAGCAATTCTCCTGCCTCAGCCTCCTGAGTAGCTGAGATTACAGGAGCCTGCCACCAC
  ACCCAGCTAATTTTTTTGTATTTTTAGTAGAGACAGGGTTTCATCATGTTGGCCAGACTGGCCTCGAATT
  CCTGACCTCAGGCAATCCACCCGCCTCGGCCTCCCAAAGAGCTGGGATTACAGGCGTGAGCCACCGCACC
  CTGCCGAAAAAAACTTTTTTTTTTTGAGACGGAGGCTCGCTCTGTCCCCCAGGCTGGAGTGCAGTGGCGA
  GATTTCAGCTCACTGCAAGCTCCGCCTCCCGGGTTCAGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTG
  GGAGCCAGCGCGCCCAGCCTAAAAAACTTTTCAAGTCAATATTACTACGATTTAACATTAGAGTGTGGAC
  ATGTGATTTAATCGCTATAGCTAAAATACGTCAAATATACGTTGTCATGTGCTTGAACATGATGCTAACC
  CTGACAGGATGAAGGAAAGTAATATTCTTTCAGTGTAGTTCAGGAGAGCATTTGTTTTCTTTTCTACCAA
  TTAACCCATCATTGCTTTTAAACAACCATCTGAAGGAGCAGAGAGGCAGGGTAGAAGACAGAAGGGGGAT
  CTATGTGGTAACTAAAGAATGTTTCTGTTTTGTTAATTATTGTGTGTGTGTGGTTTTATTGTTTGCTTAA
  GAGAATCAAAAACTGAAAAAAATGAGAATACAGGAAATGGCTCTTGTTTATTTTTTTGCTGTGTTTACAG
  CTTGTTAATGCTCTACTGTCTTTGTTTCAAGAGAGATTTGTTCACTGCCCAGCTCGTTTTGTGTCCTGAG
  CCCTATGGCCAGCCCACCTTATAAATCATGCCTGTTTAGATGTTTGATTTTGTTCTGTTTGCTATTGTTA
  TCTTAAAGGTGTATAACTCTGACATGCCAGACATCAAATTAAGCTCAAATTAAGCTCTCGTTTAAATGTT
  TAAGCACCTAATTTATATTCTAATTGATCCCAGCCACTGATGCATGTACTTTAGCTACTTCTGCTAAATA
  AGCATATTAATTTTCCACATCAGACCATCAGATCTTGAGAACCAACAGTTATCTAGAATTCCGTGTCTAC
  TAATGTTTCACCTGCATGCAGCCTTCATTAATTTTGTAGCAAAATATAAAGTGATCATTATGTAGCTTCT
  GGATTAAAAAAATTTGTGTGTGAAGTTGCTTTGTAAAGTGCATGTGGAATTAATGGGACAGTGTGCCCTT
  TGTGTTAGATGTTAGAGCAAAAGAAAGGGCTTATAGTGTTAGTATTGGAGCACTTTGAAGATAGATATTT
  TCAGAAAAGATGTAGGATTTAAAAGTTAAATTTTAAATTTTAGAAAAAGATATGATGGCAATTGGAAATA
  GTCACAATGAAGTTCTTCATCCAGTAGGTGTTTAACAGTGTTATTTTGCCACTGGTAATGTGTAAACTGT
  GAGTGATTTACAATAAATGATTATGAATTCAAAAAAAAAAAAAAAAA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for AL831891 unedited
  GTCAGAATTTGTATACGACTCATATAGGCGGCNCGCGATTCGGCACGAGGGCCACTCACT
  CTGCTCTGGGCCTACTTCTGCTTCCTCCTGGCCGCTCTGGGTGTGACAGCTGGTGCCCAT
  CGCTTGTGGAGCCACAGGTCCTACCGGGCCAAGCTGCCTCTGAGGATATTTCTGGCTGTC
  GCCAACTCCATGGCTTTCCAGAATGACATCTTCGAGTGGTCCAGGGACCACCGAGCCCAC
  CACAAGTACTCAGAGACGGATGCTGACCCCCACAATGCCCGCCGGGGCTTCTTCTTCTCC
  CATATTGGGTGGCTGTTTGTTCGCAAGCATCGAGATGTTATTGAGAAGGGGAGAAAGCTT
  GACGTCACTGACCTGCTTGCTGATCCTGTGGTCCGGATCCAGAGAAAGTACTATAAGATC
  TCCGTGGTGCTCATGTGCTTTGTGGTCCCCACGCTGGTGCCCTGGTACATCTGGGGAGAG
  AGTCTGTGGAATTCCTACTTCTTGGCCTCTATTCTCCGCTATACCATCTCACTCAACATC
  AGCTGGCTGGTCAACAGCGCCGCCCACATGTATGGAAACCGGCCCTATGACAAGCACATC
  AGCCCTCGGCAGAACCCACTCGTCGCTCTGGGTGCCATTGGTGAAGGCTTCCATAATTAC
  CATCACACCTTTCCCTTTGACTACTCTGCGAGTGAATTTGGCTTANATTTTAACCCAACC
  ACCTGGTTCATTGATTTCATGTGCTGGCTGGNGCTGGCCACTGACCGCAAACGGGCAACC
  AAGCCGATGATCGAGGCCCCGAANGCCAGGACTGGAGACAGCAGTGCTTGAACTTGAACA
  GCCATCCCACATGTCTGCCGTGAACCTCGGTCATGGGCTTGGTACATAGCTCTCTGACAT
  TGNATCGNTGGAGGGGCACAGGTGGGGAAGGACAGTCAATGTGNTTGGGAATGTTT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for AL831891 unedited
  TTCTGTGAACCCGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTGAATTCTA
  ATCATTTATTGTAAATCACTCACAGTTTACACATTACCAGTGGCAAAATAACACTGTTAA
  ACACCTACTGGATGAAGAACTTCATTGTGACTATTTCCAATTGCCATCATATCTTTTTCT
  AAAATTTAAAATTTAACTTTTAAATCCTACATCTTTTCTGAAAATATCTATCTTCAAAGT
  GCTCCAATACTAACACTATAAGCCCTTTCTTTTGCTCTAACATCTAACACAAAGGGCACA
  CTGTCCCATTAATTCCACATGCACTTTACAAAGCAACTTCACACACAAATTTTTTTAATC
  CAGAAACTACATAATGATCACTTTATATTTTGCTACAAAATTAATGAAGGCTGCATGCAG
  GTGAAACATTAGTAGACACGGAATTCTAGATAACTGTTGGTTCTCAAGATCTGATGGCCT
  GATGTGGAAAATTAATATGCTTATTTAGCAGAAGTAGCTAAAGTACATGCATCAGTGGCT
  GGGATCAATTAGAATATAAATTAGGTGTTTAAACATTTAAACGAGAGCTTAATTTGAGCT
  TAATTTGATGTCTGGCATGTCAGAGTTATACACCTTTAAGATAACAATAGCAAACAGAAC
  ANAATCAAACATCTAAACAGGCATGATTTATAAGGTGGGCTGGGCATANGGCTCANGACA
  CANAACGAGCTGGGCAGTGAACAAATCTCTCTTTGAACAAAGACAGTAGAGCATTAACAA
  GCTGTAAACCCANGCAAAAATTAACCAGACCCATTTCTGGAATCTCATTTTTTCAGTTTT
  TGATTCTCTTAGCAACAATAAACCCACACACCCATAATTACAAACAGAACCTTCTTAGTA
  CACATAGTCCCCCTCTGTCTCTACCTGCCTCCTGCTCCTCAAAGGGTGGTTAAAGCATGA
  TGGG
  
• Restriction Sites: NotI-NotI
• ACCN: AL831891
• Insert Size: 2750 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: AL831891.1, CAD38567.1
• RefSeq Size: 2287 bp
• RefSeq ORF: 2287 bp
• Locus ID: 79966
• Cytogenetics: 4q21.22
• Protein Families: Transmembrane
• Protein Pathways: Biosynthesis of unsaturated fatty acids, PPAR signaling pathway
• Gene Summary: Stearoyl-CoA desaturase (SCD; EC 1.14.99.5) is an integral membrane protein of the endoplasmic reticulum that catalyzes the formation of monounsaturated fatty acids from saturated fatty acids. SCD may be a key regulator of energy metabolism with a role in obesity and dislipidemia. Four SCD isoforms, Scd1 through Scd4, have been identified in mouse. In contrast, only 2 SCD isoforms, SCD1 (MIM 604031) and SCD5, have been identified in human. SCD1 shares about 85% amino acid identity with all 4 mouse SCD isoforms, as well as with rat Scd1 and Scd2. In contrast, SCD5 shares limited homology with the rodent SCDs and appears to be unique to primates (Wang et al., 2005 [PubMed 15907797]).[supplied by OMIM, Mar 2008]