RANTES(CCL5) (AK094877) Human Untagged Clone

CAT#: SC104452

(untagged)-Human cDNA FLJ37558 fis, clone BRCOC1000087

USD 618


Availability*
In Stock

Size
    • 10 ug

Product images

Specifications

Product Data
Product Name RANTES(CCL5) (AK094877) Human Untagged Clone
Symbol CCL5
Vector pCMV6-XL6
Sequence Data
Fully Sequenced ORF
>NCBI ORF sequence for AK094877, the custom clone sequence may differ by one or more nucleotides


ATGTTCGGCGTCTTTAGCAACGGGCATCTGTTCATCCGGGATGCCAGTGCAGTGGGCGTCATCGACAAGC
AGGAAGGCAGCCAAGAAGCCAACAGGGCAGGAGAGAATAAAGACATTTTTAGCTGCCTGGTTTCCGGCTG
CCAGGCCCAGCTGCCCTCCTGCGAAAGCATCTCTGAGAAGCAGAGCCTGGTGCTGGTGTGTCAGAAGTTG
CTGCCTCGACTTCTCCAGGGGAGGTTCCCCTCCCCAGTGCAAGACGACATAGACTCCATCCTTGTTCAGT
GTGGGGACAGCATCCGCCCAGACCCAGAAGTCCTTGGGGCCGCCAGCCAGCTGAAAGACATCTTGAGGCC
CCTGAGAACGTGTGACTCCAGATTTGCCTATCGTTACCCAGATTGCAAATATAACGATAAGTTCTGA


5' Read Nucleotide Sequence
>OriGene 5' read for AK094877 unedited
NNTTCATATCCCCCGCCCGTTGACGCAAAGGGCGGTAGGCGTGTACGGTGGGAGGTCTAT
ATAAGCAGAGCTCATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCG
GCCGCGAATTCGGCACGAGGAACGATTTGAACTATTTCTTCTACTTCACCCACATTGATG
CAGGCATGTTCGGCGTCTTTAACAACGGGCATCTGTTCATCCGGGATGCCAGTGCAGTGG
GCGTCATCGACAAGCAGGAAGGCAGCCAAGAAGCCAACAGGGCAGGAGAGAATAAAGACA
TTTTTAGCTGCCTGGTTTCCGGCTGCCAGGCCCAGCTGCCCTCCTGCGAAAGCATCTCTG
AGAAGCAGAGCCTGGTGCTGGTGTGTCAGAAGTTGCTGCCTCGACTTCTCCAGGGGAGGT
TCCCCTCCCCAGTGCAAGACGACATAGACTCCATCCTTGTTCAGTGTGGGGACAGCATCC
GCCCAGACCCAGAAGTCCTTGGGGCCGCCAGCCAGCTGAAAGACATCTTGAGGCCCCTGA
GAACGTGTGACTCCAGATTTGCCTATCGTTACCCAGAGTGCAAATATAACGATAAGTTCT
GAAGGGCTGGTGTCTAGCTGGCCTTGGGGACAACACGCTTGGCTCTCCATTCTCCCAGTC
GGGTTGCTGCAAGGTAGAAAGAAGCAGCTCTTTTTTAAAGATGAGAAGAAAGGCACACTC
ATTTCTTAGGGACTGAGACGGGGNACGTTGTGAGATACCCGGTTGGCTGTCTCTGCTGGC
TTTGGGACGTCCTGGCAAGCCCCGCGGTGGGCATCAAGACCCTGGGGTTGGTGGACGCTC
ACTCATGGTCTTGAGAGCTCAGTTTCCTCTATTCTNCACAACTCTCCTTTGGGGGGTGGA
AAGAAGACACAGATGTAGCCCC
Restriction Sites NotI-NotI     
Tag Tag Free
ACCN AK094877
ORF Size 417 bp
Insert Size 4200
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reference Data
RefSeq Size 2354
RefSeq ORF 417
Locus ID 6352
Cytogenetics 17q12
Protein Families Secreted Protein, Transmembrane, Druggable Genome
Protein Pathways Cytokine-cytokine receptor interaction, Chemokine signaling pathway, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, Cytosolic DNA-sensing pathway, Prion diseases, Epithelial cell signaling in Helicobacter pylori infection
Gene Summary This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Jul 2013].
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.