JNK1(MAPK8) (AK094000) Human Untagged Clone

CAT#: SC103740

(untagged)-Human cDNA FLJ36681 fis, clone UTERU2006547

USD 618


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Size
    • 10 ug

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Specifications

Product Data
Product Name JNK1(MAPK8) (AK094000) Human Untagged Clone
Symbol MAPK8
Vector pCMV6-XL4
Sequence Data
Fully Sequenced ORF
>NCBI ORF sequence for AK094000, the custom clone sequence may differ by one or more nucleotides


TTTTTGTTTGTACATTTTTCTCAGAAGAGGGTTCACTACTTTTATACAATTCTCAAAAGATCCCATGACC
CAAAGAAGATGATAAATAGTGTTGATGTGGCATCCACCATTAAGGTTAAGTGTGGTGTGCCCTGTGAGTC
TGAATGTCTACTTAAGAACCTTAAGTAGACATTAAGAACCTTAAGAAGGTTTTTTGTTTGTTTTTGTTTT
TTTGTTGTTGAGATGGAGCCTTGCTCCGTTGCCCAGGCTGGAGAGCAGTGGCGCAATCTCAGCTCACTGC
AACCTCTGCCTCCCAGGTTCAAGCAATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTGCAGGCGCCT
GCCCCCAAGCCCGGCTAATTTTTGTGTTTTTAGTAGAAATGGGGTTTCACCTTGTTGGTCAGGCTTGTCT
CAAACTCCTGACCTCAGGTGATCCACCCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCAC
CACACATGGCCGAAGGTTCTTCTTAAGTGGACATTCAGACTCACAAGGCACATCGCAGTTAACATCAGAA
TCACTTCTGATGATAATATAAGTGAAGAATATAAGACAGGAGGCGCATATATTAATACCAGCAGAGCAGC
TCCCAGTGTGTCTCTTCAGTTGGAACAGTTGTTGCAGTGGTCTACTTGCTGTCCAGAAGCCTGATAAGAG
AAAAAGATTCCCATGGAGAAATGTTCTTCGAAGTGATAACCATGCTTACTCATAAGGAGTTGAAATGTAG
CTTACCTGCTAGTTTTCCTCCAATAAAAATGTGTTTATCTTTCATTCTGATTTGTTGTGAAGCTTTTGCA
CACTCTAATTTAAATCTTGGTAGCATATATCTAGTTGAGTACCCACAGTGCACCAGGCTCTATTCCAGGG
CCCAGGAAATGGAAGTCAGTAAGACACGTGGTTCAAGCCCTCCCTGAGACAGATGGTAGTACAGAATGGT
ATGTGGTATGATGTGCTGTAGCACAAGTTGCTGGTAGAGTGAAAAAGAAAGCTTCTACCCCAGCACTATC
AAACCAACTTCAGAAACAGTGAATTACAGGAAAGATTAGTACTTCCTTTTAATATGATCCATTGTTGAGT
GTCAAGGAATTGTTATTAATTAACATCCTTGAATCTTAGGCCGACATTTAACTGACTGTCATTGTAAGGA
CACTGTTTGAAGTACTTCACATGTATAAAAATTTCCACTTAAACCATACATGCGTTGTGAGATTGGCTCT
TAGACTTTGAAAAGTTCATTTTTGTTTACTTCTTTTACAGAATTGATATATAAGGAAGTTATGGACTTGG
AGGAGAGAACCAAGAATGGAGTTATACGGGGGCAGCCCTCTCCTTTAGGTGCAGCAGTGATCAATGGCTC
TCAGCATCCATCATCATCGTCGTCTGTCAATGATGTGTCTTCAATGTCAACAGATCCGACTTTGGCCTCT
GATACAGACAGCAGTCTAGAAGCAGCAGCTGGGCCTCTGGGCTGCTGTAGATGACTACTTGGGCCATTGG
GGGGTGGGAGGGATGGGGAGTCGGTTAGTCATTGATAGAACTACTTTGAAAACAATTCAGTGGTCTTATT
TTTGGGTGATTTTTCAAAAAATGTAGAATTCATTTTGTAGTAAAGTAGTTTATTTTTTTTAATTTCAAGT
GATGTAATTTAAAACCTAAGTTGTGTTTCAAAACAGCAACAAAACTGTATTGTATTTTTTTTGCTGTAAT
TAACTGTATAATGTAAACCTAATTATTTTATCATGGTTTAAATTTTTTGCATATTTGCTTTATCTTATGC
TGCTGATTTTTTTAACTGAATTTGTAAGATTTTGTTTATCAAAGCAACTATTATGTGGTAACTTGCCTAT
ATCATGAATTATTTAAGATTTTTATAGTTTTTTTTAATTAGAATTTATTTCAGATGTTTTGTTCATGATA
CTATCCTTCAGGGTTATGTGCTTATCAATGAAATAACCCCAGAGGAGTGAGGGAAAATAACTTGTAGCCA
GTTATATTCAGGAATAACTACTGTAAATGATGAACGTGTTAGGAGACCTCCAATATTTGCTACTTGCCAA
TCCTAATTTAGTTACAAGAATTGGTAGGCAATCCTACTTAATTTTGGCAAAAGCCCCGTCATCTAAATGG
CAGAATAACTCAGAGCATGTCTTTGAAGATGCTGGGCGTCTACCACCACCTTATGTCCCCACCCTACCCA
ACAAAAATAAGTAAAAAGAATATGGTGTATTCTACAAATTTGTGGCATGCTCAAAGTTTATGATCACATA
AAGGCAAGAGGATACTTCATGAATAATACATTTCAATGCAAATAAACAGATGGTTCACTTCT


5' Read Nucleotide Sequence
>OriGene 5' read for AK094000 unedited
GGTGCACATTTGTATACGACTCATATAGGCGGCCGCGAAATTCGCACGAGGGTTTTTAGT
AGAAAGGGGTTTCACCTTGTTGGTCAGGCTTGTCTCAAACTCCTGACCTCAGGTGATCCA
CCCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCACACATGGCCGAAG
GTTCTTCTTAAGTAGACATTCAGACTCACAAGGCACATCGCAGTTAACATCAGAATCACT
TCTGATGATAATATAAGTGAAGAATATAAGACAGGAGGCGCATATATTAATACCAGCAGA
GCAGCTCCCAGTGTGTCTCTTCAGTTGGAACAGTTGTTGCAGTGGTCTACTTGCTGTCCA
GAAGCCTGATAAGAGAAAAAGATTCCCATGGAGAAATGTTCTTCGAAGTGATAACCATGC
TTACTCATAAGGAGTTGAAATGTAGCTTACCTGCTAGTTTTCCTCCAATAAAAATGTGTT
TATCTTTCATTCTGATTTGTTGTGAAGCTTTTGCACACTCTAATTTAAATCTTGGTAGCA
TATATCTAGTTGAGTACCCACAGTGCACCAGGCTCTATTCCAGGGCCCAGGAAATGGAAG
TCAGTAAGACACGTGGTTCAAGCCCTCCCTGAGACAGATGGTAGTACAGAATGGTATGTG
GTATGATGTGCTGTAGCACAAGTTGCTGGTAGAGTGAAAAAGAAAGCTTCTACCCCAGCA
CTATCAAACCAACTTCAGAAACAGTGAATTACAGGAAAGATTAGTACTTNCTTTTATATG
ATCCATTGTTGAGTGTCAAGGAATTGNTATTAANTAACATCCTTGAATCTTTAGCCGACA
TTTAACTGACTGTCATTGTAAGGACACTGTTTGAAGTACTTCACATGTATAAAAATTTCC
ACTTAAACATACATGCGTTGTGAGAATGCCTCTTAGAA
Restriction Sites NotI-NotI     
Tag Tag Free
ACCN AK094000
ORF Size 2372 bp
Insert Size 6000
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reference Data
RefSeq Size 2372
RefSeq ORF 2372
Locus ID 5599
Cytogenetics 10q11.22
Protein Families Protein Kinase, ES Cell Differentiation/IPS, Druggable Genome
Protein Pathways MAPK signaling pathway, ErbB signaling pathway, Wnt signaling pathway, Focal adhesion, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Fc epsilon RI signaling pathway, Neurotrophin signaling pathway, Insulin signaling pathway, GnRH signaling pathway, Progesterone-mediated oocyte maturation, Adipocytokine signaling pathway, Type II diabetes mellitus, Epithelial cell signaling in Helicobacter pylori infection, Pathways in cancer, Colorectal cancer, Pancreatic cancer
Gene Summary The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Apr 2016].
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