XIAP (AK098439) Human Untagged Clone

CAT#: SC101707

(untagged)-Human cDNA FLJ25573 fis, clone JTH06531

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: XIAP
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for AK098439, the custom clone sequence may differ by one or more nucleotides
  
  
  ATTTCCATGAGAACAAAGGCTTATTCCTTTAACTTAAACCCCAAACTTTGTTATTTTAATTATTTTCAGG
  CAATCATCTTTATATACTTTCCTTACAAACCCAGTGGTTGAGAGCATAGGCCTTGGTGGCAGGTGCATCT
  GGGCTTGGGGGCTTCTGCCACACTTACTACTCTGTGACTTGGGAAGCTCTTAAGGCTCCCAAGGCTCCGT
  TTCTTATGTGGAAGAAGAATAGCAGGAGGACTCACCTCTGCGGGTTGTTGTGAGGATTAACTGGGTGATG
  ACTGTAAGCAGCTGGGAGAGTGCCTTGTGTGCAGTGACCACTGTTGCTGCCACCATGATTATGTCACCTC
  TCAACATGGGGTGGTGGGAGGCCCTGTGGATGAGGCCAAGGCTGCCTGCACTGAGTGTCCCAGGCCTTAT
  AGCTTTCCACATTCTCACGTCTGCTGCCACATGATATACAAGTAAATGTATTAGAAGTTGGTGTTCATAA
  AATACTTCTTTTTTTTTTTTTTTTGAGATGGAGTCTCGCTCCGTCACCCAGGCTGGAGTGCAGTGGCGCC
  ATCTCCCAGGCTCAAGGGATCCTCCTGCCTCGGCCTGCCAAGTAGCTGGGACTACAAGTGCACACCAGTA
  TGCCCAACTAATTTTTTGTATTTTTAGAACAGGTGTGGTTTCACCATATTGCCCAGGCTGGTCTCGAGCT
  CCTGAGCTCAGGCAATCCGCCTGCCTCAACCTCCCAAAGTGCTGGGATTACAGGTGTGAGCATCCAGCCA
  GAAAATGATTTGCTTTCTAGACCCATATCACCTCTCTCCATCTACATCTCTAGTATTTAAATTCAACACA
  ATTCTAGATAGCTGAAACAGCCCAAAATATGTGTTTAGAATACTTAGAGTTTGTTATAAATAACCCTCTG
  TTTAGAATTTGCCCAGTGAAATTCTCTAATAATACTTAAAACTCTTTACTAAAGTTGAATTTTCCTTTTT
  TTTCATTGAAATAGCAAAGGTAGTAATCTGTATTGGTCAAAGAAACGAGATAATTCCTAGATCTCTGTTT
  TAGACCAGTAGACCTAACTGTGCTTTCTTAACTTGGATGTTACATGAAACTTAAAAACAAACAAATATGT
  GTTACAAGTACTTGTGTGTACGTGCATGTGTGTTTGTGCATGTGTCTGTGTGTGTGGAACTTTTGTACCT
  TTGCATAAAGAAGGTTATTTAACAAAGTGGTACAAACAGTGAACTACTTAATCCTTCTATGGTATCATAC
  ACTTCTTTTCCTGGTTAGGTTATGAGACTGGCAGAGGTAGGAGTATATAATGTGCTCAGCTTGTCTTGAT
  TTCAATAAGACATTTGATAAAGTCATTCTTGATCTCTGAATGTGAAAAGGAAGTAGAACAGCCGGGCGCG
  GTGGCTCACGCCTGTAATCCCAGGACTTTGGGAGGCCAAGGCGGGCAGATCACCTGAGGTCGGCAGTTTG
  AGACCAGCCTGACCAACGTGGAGAAACCCCGTCTCTATTAAAAATACAAAATTAGCCGGGCATGGTGGCA
  CATGTGTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCTCTTGAACCCAGGAGGCGGAGGTTG
  CGGTGAGCCGAGATGGTGCCGTTGCACTCCAGCCGGGCAACAAGGGCTAAACTCCATCTCAAAAGAAAAG
  AAAGAAAGGGAAGTAGAAGTAGGATTTAACAAAGGACCGAGAAGTCGGCTGAATAGCCAGGTTCAGACAG
  TGTTGGCAAGAACGGATCTTTGGCAAGATCACTTAAGGTGAGCTACTCTAGCAGCATCCTGTTTGACATT
  TGTATCCATAACTTGAATAAAAATATAGAAGGCAAAGAAGAGTGCTGGGCAAGATGTGTTGGGTGTTAGA
  TCTGCAATACTCTTCATAGTGTAATGGCTAAATGTAAAGTCTTACGTCTCGGTTCAAGAAAGCACGTTGC
  TATATGAAATTTCAGAAAAAAGTTTTGTTGCGGGGGGTGGGATATTGATCATTTGAACATATGCCAGTTG
  TTTCTCCTGCCCTAGGGGAGGTTGGCACGGCAACCTTCCCACTCCGTAGGTGGGTAGCCTTGCTGATGGG
  GCACGTCGTCACCAAGGGACCTGATTGTTGTCATGGTTTTGTCTTGTCCTCCTCCCTGGTGAAAGTCTAC
  TGCAGTTTTATTCTCAGCTCTGGAAGGAGAGGGAACGAGCCTCTGCCTGTGTGTCCTGACCCCTCTTGCC
  TTGTTTTTGATCTGCTCAGGCCGGGTGCAGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCAAAGG
  CAGGTGGATCACTTGAGGTCAGGAGTTCAAGACTAGCCTGGCCAACATGGTGAAACCCCGTCTCTACTAA
  AAATACAAAAATTAGCCAAGTGTGTTGGTGGGCCCCTGTAATCCCAGCTACTCGGGAGGTTGAGGGAGGA
  GAATCACTTGACCCCAGGAGGCGGAGGTTGAAGTGAGCCAGGATTGTGCCACTGTACTCCAGCCTGGGCG
  ACAGAGGGGGACTCTGTCTCAC
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for AK098439 unedited
  GTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCCTCGTGCCGAATTCGG
  CACGAGGGTTGGGTGTTAGATCTGCAATACTCTTCATAGTGTAATGGCTAAATGTAAAGT
  CTTACGTCTCGGTTCAAGAAAGCACGTTGCTATATGAAATTTCAGAAAAAAGTTTTGTTG
  CGGGGGGTGGGATATTGATCATTTGAACATATGCCAGTTGTTTCTCCTGCCCTAGGGGAG
  GTTGGCACGGCAACCTTCCCACTCCGTAGGTGGGTAGCCTTGCTGATGGGGCACGTCGTC
  ACCAAGGGACCTGATTGTTGTCATGGTTTTGTCTTGTCCTCCTCCCTGGTGAAAGTCTAC
  TGCAGTTTTATTCTCAGCTCTGGAAGGAGAGGGAACGAGCCTCTGCCTGTGTGTCCTGAC
  CCCTCTTGCCTTGTTTTTGATCTGCTCAGGCCGGGTGCAGTGGCTCACGCCTGTAATCCC
  AGCACTTTGGGAGGCAAAGGCAGGTGGATCACTTGAGGTCAGGAGTTCAAGACTAGCCTG
  GCCAACATGGTGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCCAAGTGTGTTGGTG
  GGCCCCTGTAATCCCAGCTACTCGGGAGGTTGAGGGAGGAGAATCACTTGACCCCAGGAG
  GCGGAGGTTGAAGTGAGCCAGGATTGTGCCACTGTACTCCAGCCTGGGCGACAGAGGGGG
  GACTCTGTCTCACANNAAATAAAAAATTAAAAAAAAGGTCTGCTCAGAATAGGGGAAACA
  CGGGATCAAGATCATTANAGATTTATAGGCTGGGATGCACACCATGTCTTCAGAGCTAGC
  CCGGCTGTGTCTTCTGCCCGTTTCTTTACTGGTGAATACCCTTTCGNNTGACCANCANNT
  GATGTTCTCTCCTA
  
• Restriction Sites: NotI-NotI
• ACCN: AK098439
• Insert Size: 4000 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: AK098439.1
• RefSeq Size: 2542 bp
• RefSeq ORF: 2542 bp
• Locus ID: 331
• Cytogenetics: Xq25
• Protein Families: Druggable Genome
• Protein Pathways: Apoptosis, Focal adhesion, NOD-like receptor signaling pathway, Pathways in cancer, Small cell lung cancer, Ubiquitin mediated proteolysis
• Gene Summary: This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.[provided by RefSeq, Feb 2011]