STK36 (NM_015690) Human Untagged Clone

CAT#: SC101100

STK36 (untagged)-Human serine/threonine kinase 36 (STK36)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: STK36
• Synonyms: FU
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_015690, the custom clone sequence may differ by one or more nucleotides
  
  
  GAGTAAAATTGCGTCCCAGATGTTGTGGAACTGTCCCTGGATCTATAGCTCTTCACCGTCTCTACTTTCT
  TCCTTCTAAGAGATCCTGAAACCTCTGTCATGGAAAAGTACCACGTGTTGGAGATGATTGGAGAAGGCTC
  TTTTGGGAGGGTGTACAAGGGTCGAAGAAAATACAGTGCTCAGGTCGTGGCCCTGAAGTTCATCCCAAAA
  TTGGGGCGCTCAGAGAAGGAGCTGAGGAATTTGCAACGAGAGATTGAAATAATGCGGGGTCTGCGGCATC
  CCAACATTGTGCATATGCTTGACAGCTTTGAAACTGATAAAGAGGTGGTGGTGGTGACAGACTATGCTGA
  GGGAGAGCTCTTTCAGATCCTAGAAGATGACGGAAAACTTCCTGAAGACCAGGTTCAGGCCATTGCTGCC
  CAGTTGGTGTCAGCCCTGTACTATCTGCATTCCCACCGCATCCTACACCGAGATATGAAGCCTCAGAACA
  TCCTCCTCGCCAAGGGTGGTGGCATCAAGCTCTGTGACTTTGGATTTGCCCGGGCTATGAGCACCAATAC
  AATGGTGCTGACATCCATCAAAGGCACACCACTCTATATGTCTCCAGAGCTGGTGGAGGAGCGACCATAC
  GACCACACAGCGGACCTCTGGTCTGTTGGCTGCATACTATATGAACTGGCAGTAGGCACCCCTCCCTTCT
  ATGCTACAAGCATCTTTCAGCTGGTCAGCCTCATTCTCAAGGACCCTGTGCGCTGGCCCTCAACCATCAG
  TCCCTGCTTTAAGAACTTCCTGCAGGGACTGCTCACCAAAGACCCACGGCAGCGACTGTCCTGGCCAGAC
  CTCTTATATCACCCCTTTATTGCTGGTCATGTCACCATAATAACTGAGCCAGCAGGCCCAGATTTGGGGA
  CCCCATTCACCAGCCGCCTACCCCCAGAACTTCAGGTCCTAAAGGACGAACAGGCCCATCGGTTGGCCCC
  CAAGGAAACATCAGAACACAGGACCTGCCCTTGAGCAAGAGGACAAGACCAGCAAGGTGGCTCCTGGCAC
  AGCCCCTCTGCCCAGACTCGGGGCCACTCCTCAGGAATCAAGCCTCCTGGCCGGGATCTTAGCCTCAGAA
  TTGAAGAGCAGCTGGGCTAAATCAGGGACTGGAGAGGTGCCCTCTGCACCTCGGGAAAACCGGACCACCC
  CAGATTGTGAACGAGCATTCCCAGAGGAGAGGCCAGAGGTGCTGGGCCAGCGGAGCACTGATGTAGTGGA
  CCTGGAAAATGAGGAGCCAGACAGTGACAATGAGTGGCAGCACCTGCTAGAGACCACTGAGCCTGTGCCT
  ATTCAACTGAAGGCTCCTCTCACCTTGCTGTGTAATCCTGACTTCTGCCAGCGCATCCAGAGTCAGCTGC
  ATGAAGCTGGAGGGCAGATCCTGAAAGGCATCTTGGAGGGTGCTTCCCACATCCTGCCTGCATTCCGGGT
  CCTGAGCAGTCTTCTCTCCAGCTGCAGTGATTCTGTTGCCTTGTATTCCTTCTGCCGGGAGGCAGGGCTT
  CCTGGGCTGCTGCTGAGTCTACTCAGGCACAGTCAGGAGAGCAACAGCCTCCAGCAGCAATCTTGGTATG
  GGACCTTCTTACAGGACCTGATGGCTGTGATTCAGGCCTACTTTGCCTGTACCTTCAATCTGGAGAGGAG
  CCAGACAAGTGACAGCCTGCAGGTGTTTCAGGAGGCTGCCAACCTTTTTCTGGACCTGTTGGGGAAACTG
  CTGGCCCAACCAGATGACTCTGAGCAGACTTTGCGGAGGGACAGCCTTATGTGCTTTACTGTCCTGTGCG
  AAGCCATGGATGGGAACAGCCGGGCCATCTCCAAAGCCTTTTACTCCAGCTTGCTGACGACACAGCAGGT
  TGTCTTGGATGGGCTCCTTCATGGCTTGACAGTTCCACAGCTCCCTGTCCACACTCCCCAAGGTAACCAG
  AGTGGAGAAGGGAGGTTCTCTTGACTTACTTGTTGCATAGGTCAGGCTCCGCTCTTTCTATTGCCATCAC
  CTAGATCGCACCTGGCATTTAGTAGGTGCTCAATAAATAACTGTGAACTGAGAGAATGAATGGGGATCTG
  AGGGAAACAAACAGACCTCATCCTGCATTCTTCCCACTCCCTTAGGTTCCCTACTCCTGCTGCCATGTCG
  GTGAGTACTGGTGCTATTGTCTAGGGCAAGAGCCTCAGGCCTTTGGAGTTACTCTTTGCTTTTCTCCACA
  GGAGCCCCGCAAGTGAGCCAGCCACTGCGAGAGCAGAGTGAGGATATACCTGGAGCCATTTCCTCTGCCC
  TGGCAGCCATATGCACTGCTCCTGTGGGACTGCCCGACTGCTGGGATGCCAAGGAGCAGGTCTGTTGGCA
  TTTGGCAAATCAGCTAACTGAAGACAGCAGCCAGCTCAGGCCATCCCTCATCTCTGGCCTGCAGCATCCC
  ATCCTGTGCCTGCACCTTCTCAAGGTTCTATACTCCTGCTGCCTTGTCAGTGAGGGCCTGTGCCGTCTTC
  TGGGGCAGGAGCCCCTGGCCTTGGAATCCCTGTTTATGTTGATTCAGGGCAAGGTAAAAGTAGTAGATTG
  GGAAGAGTCTACTGAAGTGACACTCTACTTCCTCTCCCTTCTTGTCTTTCGGCTCCAAAACCTGCCTTGT
  GGAATGGAGAAGCTAGGCAGTGACGTTGCTACTCTCTTTACCCATTCGCATGTCGTCTCTCTTGTGAGTG
  CAGCAGCCTGTCTATTGGGACAGCTTGGTCAGCAAGGGGTGACCTTTGACCTCCAGCCCATGGAATGGAT
  GGCTGCAGCCACACATGCCTTGTCTGCCCCTGCAGAGGTTCGGTTGACTCCACCAGGTAGTTGTGGATTC
  TATGATGGCCTCCTTATCCTTCTGTTGCAGCTCCTCACTGAGCAGGGGAAGGCTAGCCTAATCAGGGATA
  TGTCCAGTTCAGAAATGTGGACCGTTTTGTGGCACCGCTTCTCCATGGTCCTGAGGCTCCCCGAGGAGGC
  ATCTGCACAGGAAGGGGAGCTTTCGCTATCCAGTCCACCAAGCCCTGAGCCAGACTGGACACTGATTTCT
  CCCCAGGGCATGGCAGCCCTGCTGAGCCTGGCCATGGCCACCTTTACCCAGGAGCCCCAGTTATGCCTGA
  GCTGCCTGTCCCAGCATGGAAGTATCCTCATGTCCATCCTGAAGCATCTGCTTTGCCCCAGCTTCCTGAA
  TCAACTGCGCCAGGCGCCTCATGGGTCTGAGTTTCTCCCTGTCGTGGTGCTCTCTGTCTGCCAGCTCCTT
  TGCTTCCCCTTTGCGCTGGACATGGATGCTGACCTCCTTATAGGTGTCTTGGCCGACCTCAGGGACTCAG
  AAGTTGCAGCCCATCTGCTGCAGGTCTGCTGCTACCATCTTCCGTTGATGCAAGTGGAGCTGCCCATCAG
  CCTTCTCACACGCCTGGCCCTCATGGATCCCACCTCTCTCAACCAGTTTGTGAACACAGTGTCTGCCTCC
  CCTAGAACCATCGTCTCGTTTCTCTCAGTTGCCCTCCTGAGTGACCAGCCACTGTTGACCTCCGACCTTC
  TCTCTCTGCTGGCCCATACTGCCAGGGTCCTGTCTCCCAGCCACTTGTCCTTTATCCAAGAGCTTCTGGC
  TGGCTCTGATGAATCCTATCGGCCCCTGCGCAGCCTCCTGGGCCACCCAGAGAATTCTGTGCGGGCACAC
  ACTTATAGGCTCCTGGGACACTTGCTCCAACACAGCATGGCCCTGCGTGGGGCACTGCAGAGCCAGTCTG
  GACTGCTCAGCCTTCTGCTGCTTGGGCTTGGAGACAAGGATCCTGTTGTGCGGTGCAGTGCCAGCTTTGC
  TGTGGGCAATGCAGCTTACCAGGCTGGTCCTCTGGGACCTGCCCTGGCAGCTGCAGTGCCCAGTATGACC
  CAGCTGCTTGGAGATCCTCAGGCTGGTATCCGGCGCAATGTTGCATCAGCTCTGGGCAACTTGGGACCTG
  AAGGTTTGGGAGAGGAGCTGTTACAGTGCGAAGTACCCCAGCGGCTCCTAGAAATGGCATGTGGAGACCC
  CCAGCCAAATGTGAAGGAGGCTGCCCTCATTGCCCTCCGGAGCCTGCAACAGGAGCCTGGCATCCATCAG
  GTACTGGTGTCCCTGGGTGCCAGTGAGAAACTATCCTTGCTCTCTCTGGGGAATCAGTCACTGCCACACA
  GCAGTCCTAGGCCTGCCTCTGCCAAACACTGCAGGAAACTCATTCACCTCCTGAGGCCAGCCCATAGCAT
  GTGATTCCAGATTCCTGCGGTCCAGCCTCCAACTTTGGTTGCCAGCTCTTTCTTATTCTACTACACAAGC
  CGCCAACTCAACTGAGAGCTAAAGAGACTAGAAA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_015690 unedited
  NNTTGTCGAATTTGTATACGACTCCTATAGGCGGCCGCGNAATTCGCACGAGGGGCCTGA
  TGGCCCTGAGCAGTTCGGATGTGTCCCAGGAAGTGCCCATGTGTGGTCCGCCGTCCATTC
  CACACCTCTGAGCGCCTTTGTCCTCTGAACTTCTCACCAGTTCTAGCGAGTAAAATTGCG
  TCCCAGATGTTGTGGAACTGTCCCTGGATCTATAGCTCTTCACCGTCTCTACTTTCTTCC
  TTCTAAGAGATCCTGAAACCTCTGTCATGGAAAAGTACCACGTGTTGGAGATGATTGGAG
  AAGGCTCTTTTGGGAGGGTGTACAAGGGTCGAAGAAAATACAGTGCTCAGGTCGTGGCCC
  TGAAGTTCATCCCAAAATTGGGGCGCTCAGAGAAGGAGCTGAGGAATTTGCAACGAGAGA
  TTGAAATAATGCGGGGTCTGCGGCATCCCAACATTGTGCATATGCTTGACAGCTTTGAAA
  CTGATAAAGAGGTGGTGGTGGTGACAGACTATGCTGAGGGAGAGCTCTTTCAGATCCTAG
  AAGATGACGGAAAACTTCCTGAAGACCAGGTTCAGGCCATTGCTGCCCAGTTGGTGTCAG
  CCCTGTACTATCTGCATTCCCACCGCATCCTACACCGAGATATGAAGCCTCAGAACATCC
  TCCTCGCCAAGGGGTGGTGGCATCAAGCTCTGTGACTTTGGATTTGCCCGGGCTATGAGC
  ACCAATACAATGGGTGCTGACATCCATCAAAGGCACACCACTNCTATATGTCTCCAGAGC
  TGGGTGGAGGAGCGACCATACGACCACACAGCGGACCTCTTGGTTCTGTTGGCTGCATAC
  TATATGAAACTGGCAGTAGGCACCCCTTCCTTTCTATGCTACAGCATCTT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_015690 unedited
  AAAAAAAACCNNNANNNAANAAAAANNAAAATTTACTTAGGCCGCGGCCGCATACTANGA
  TCGATTTTTTTTTTTTTTTTTTTGTGTGAACACGATACCAGCACCTCCAACACCACATAG
  AAGCTGAAAGAGGGGTTGAGCCTCTCAACCCTTGTCCTGGGAGCTTCAAGTATGGTGAGG
  CACAACTTTTATTAAAAGAGTTTACAAACAGAACTATTAAACACACACACACATACACAC
  ACACATATACACACACACCCCAAAAAAAGATACACTCTCCACGCCCACCCACAGATAGGA
  ATGTTGGCTAAGGGATAATCCCTCAATAACAGGGACTGATGGCATTGATCCCCACAGCCT
  AGAGCTGAGACAGGCTCTGTCTTCATCACTGTCCTGGGGCCAGCACGTCTAAGGCAAAAA
  CCTGCTGGGAAGATTAAAGGAGCTCCAGAAAGGAAGAGATCTTTCAGGTTGAGGTTTTTC
  CCTAAGGTCCGTGAGGCAGGTCCCTAGAGTTAAAGGCACATTATTGGAGAAAAGGCCCCT
  GGATGTAGAGAAGAAAGGACTCTTCTCTGGCACCAACAGCAATAAAATTTACTGGTTGAA
  AACATCCTGCATCTGGGAGAACGAAGAAGCTNTATATATAAATCTCTTCTAGTTTCTTGT
  TCTCAGNTGAGTTGGCAGCTTATCTCTTTTCTAGGCTCTTTAGCTCTCAGTTGAGTTGGC
  GGCTCTGGTAATAAAAATAGAAAGAGCTGGCAACCAAATTGTGAGCCTGTACCGCAGAAT
  CTGGGATACATGCTATGGGCTGGCCTTAAGAGGTGAATGAAGTTCCTGCACCGTTTGGCA
  AAGCCAGCCTACGAATCGTGGGTTGGAGAGACTGATTCCCACAAAAAGCAGGATAGTTCT
  TCATGTCCCCAAGGACACACACCCTGTGGATGCCAGCTTCTGTTCAAC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_015690
• Insert Size: 4700 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_015690.2, NP_056505.1
• RefSeq Size: 4887 bp
• RefSeq ORF: 3948 bp
• Locus ID: 27148
• UniProt ID: Q9NRP7
• Cytogenetics: 2q35
• Domains: pkinase, TyrKc, S_TKc
• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Basal cell carcinoma, Hedgehog signaling pathway, Pathways in cancer
• Gene Summary: This gene encodes a member of the serine/threonine kinase family of enzymes. This family member is similar to a Drosophila protein that plays a key role in the Hedgehog signaling pathway. This human protein is a positive regulator of the GLI zinc-finger transcription factors. Knockout studies of the homologous mouse gene suggest that defects in this human gene may lead to congenital hydrocephalus, possibly due to a functional defect in motile cilia. Because Hedgehog signaling is frequently activated in certain kinds of gastrointestinal cancers, it has been suggested that this gene is a target for the treatment of these cancers. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1, also known as long form or L-FU).