BORCS5 (NM_001300742) Human Tagged ORF Clone

CAT#: RG236297

LOH12CR1 (tGFP-tagged) - Human loss of heterozygosity, 12, chromosomal region 1 (LOH12CR1), transcript variant 2

Product Images

Circular map for RG236297

Specifications

Product Data

• Tag: TurboGFP
• Symbol: BORCS5
• Synonyms: LOH1CR12; LOH12CR1
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG236297 representing NM_001300742.
  Blue=ORF Red=Cloning site Green=Tag(s)
  
  GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG
  GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC
  ATGACTCCTTCACCAGCCAAGCATAGAGCCAAGATGGATGATATTGTGGTTGTAGCTCAGGGCTCCCAG
  GCCTCACGGAACGTCAGCAACGATCCCGATGTCATCAAGTTGCAAGAGATTCCAACCTTCCAGCCCCTT
  TTGAAAGGGCTATTGAGTGGCCAGACTTCCCCAACAAATGCCAAATTGGAGAAACTGGACTCTCAGCAG
  GTGTTGCAGCTCTGCCTCCGATATCAAGATCACCTGCATCAGTGTGCAGAGGCCGTTGCTTTTGACCAG
  AATGCTTTGGTTAAACGAATCAAAGAGATGGATCTGTCTGTAGAAACTCTGTTCAGCTTCATGCAGGAG
  CGCCAGAAAAGATACGCCAAGTATGCCGAGCAGATCCAGAAAGTGAACGAGATGTCCGCCATCCTCCGC
  CGCATACAGATGGGCATCGACCAGACTGTGCCCCTGCTGGACAGGCTCAACAGCATGCTGCCCGAGGGC
  GAGCGGCTGGAGCCCTTCAGCATGAAGCCCGACCGCGAGCTCAGGCTG
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAAAC
  
  Protein Sequence

  >Peptide sequence encoded by RG236297
  Blue=ORF Red=Cloning site Green=Tag(s)
  
  MTPSPAKHRAKMDDIVVVAQGSQASRNVSNDPDVIKLQEIPTFQPLLKGLLSGQTSPTNAKLEKLDSQQ
  VLQLCLRYQDHLHQCAEAVAFDQNALVKRIKEMDLSVETLFSFMQERQKRYAKYAEQIQKVNEMSAILR
  RIQMGIDQTVPLLDRLNSMLPEGERLEPFSMKPDRELRL
  TRTRPLEMESDESGLPAMEIECRITGTLNGVEFELVGGGEGTPEQGRMTNKMKSTKGALTFSPYLLSHV
  MGYGFYHFGTYPSGYENPFLHAINNGGYTNTRIEKYEDGGVLHVSFSYRYEAGRVIGDFKVMGTGFPED
  SVIFTDKIIRSNATVEHLHPMGDNDLDGSFTRTFSLRDGGYYSSVVDSHMHFKSAIHPSILQNGGPMFA
  FRRVEEDHSNTELGIVEYQHAFKTPDADAGEERV
  
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001300742
• ORF Size: 531 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).

Reference Data

• RefSeq: NM_001300742.3
• RefSeq Size: 1701 bp
• RefSeq ORF: 534 bp
• Locus ID: 118426
• UniProt ID: Q969J3
• Cytogenetics: 12p13.2
• MW: 20.7 kDa
• Gene Summary: As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor. Thereby, it may indirectly play a role in cell spreading and motility.[UniProtKB/Swiss-Prot Function]