SHOX2 (NM_006884) Human Tagged ORF Clone

CAT#: RG219520

Specifications

Product Data

• Product Name: SHOX2 (NM_006884) Human Tagged ORF Clone
• Symbol: SHOX2
• Synonyms: OG12; OG12X; SHOT
• Vector: pCMV6-AC-GFP
• Sequence Data:
  ORF Nucleotide Sequence

  >RG219520 representing NM_006884
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGAAGAACTTACGGCGTTCGTCTCCAAGTCTTTTGACCAGAAAGTGAAGGAGAAGAAGGAGGCGATCA
  CGTACCGGGAGGTGCTGGAGAGCGGGCCGCTGCGCGGGGCCAAGGAGCCGACCGGCTGCACCGAGGCGGG
  CCGCGACGACCGCAGCAGCCCGGCAGTCCGGGCGGCCGGCGGAGGCGGCGGCGGAGGAGGCGGAGGCGGC
  GGCGGAGGAGGCGGAGGAGGTGTAGGAGGAGGTGGAGCAGGCGGAGGAGCTGGAGGAGGGCGCTCTCCCG
  TCCGGGAGCTGGACATGGGCGCCGCCGAGAGAAGCAGGGAGCCCGGCAGCCCGCGGCTGACGGAGGTGTC
  CCCGGAGCTGAAAGATCGCAAAGACGATGCGAAAGGGATGGAGGACGAAGGCCAGACCAAAATCAAGCAG
  AGGCGAAGTCGGACCAATTTCACCCTGGAACAACTCAATGAGCTGGAGAGGCTTTTTGACGAGACCCACT
  ATCCCGACGCCTTCATGCGAGAGGAACTGAGCCAGCGACTGGGCCTGTCGGAGGCCCGAGTGCAGGTTTG
  GTTTCAAAATCGAAGAGCTAAATGTAGAAAACAAGAAAATCAACTCCATAAAGGTGTTCTCATAGGGGCC
  GCCAGCCAGTTTGAAGCTTGTAGAGTCGCACCTTATGTCAACGTAGGTGCTTTAAGGATGCCATTTCAGC
  AGGATAGTCATTGCAACGTGACGCCCTTGCCCTTTCAGGTTCAGGCGCAGCTGCAGCTGGACAGCGCTGT
  GGCGCACGCGCACCACCACCTGCATCCGCACCTGGCCGCGCACGCGCCCTACATGATGTTCCCAGCACCG
  CCCTTCGGACTGCCGCTCGCCACGCTGGCCGCGGATTCGGCTTCCGCCGCCTCGGTAGTGGCGGCCGCAG
  CAGCCGCCAAGACCACCAGCAAGGACTCCAGCATCGCCGATCTCAGACTGAAAGCCAAAAAGCACGCCGC
  AGCCCTGGGTCTG
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG219520 representing NM_006884
  Red=Cloning site Green=Tags(s)
  
  MEELTAFVSKSFDQKVKEKKEAITYREVLESGPLRGAKEPTGCTEAGRDDRSSPAVRAAGGGGGGGGGGG
  GGGGGGGVGGGGAGGGAGGGRSPVRELDMGAAERSREPGSPRLTEVSPELKDRKDDAKGMEDEGQTKIKQ
  RRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQLHKGVLIGA
  ASQFEACRVAPYVNVGALRMPFQQDSHCNVTPLPFQVQAQLQLDSAVAHAHHHLHPHLAAHAPYMMFPAP
  PFGLPLATLAADSASAASVVAAAAAAKTTSKDSSIADLRLKAKKHAAALGL
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• Tag: TurboGFP
• ACCN: NM_006884
• ORF Size: 993 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.

Reference Data

• RefSeq: NM_006884.1, NP_006875
• RefSeq Size: 1948
• RefSeq ORF: 996
• Locus ID: 6474
• Cytogenetics: 3q25.32
• Protein Families: Transcription Factors
• Gene Summary: This gene is a member of the homeobox family of genes that encode proteins containing a 60-amino acid residue motif that represents a DNA binding domain. Homeobox genes have been characterized extensively as transcriptional regulators involved in pattern formation in both invertebrate and vertebrate species. Several human genetic disorders are caused by aberrations in human homeobox genes. This locus represents a pseudoautosomal homeobox gene that is thought to be responsible for idiopathic short stature, and it is implicated in the short stature phenotype of Turner syndrome patients. This gene is considered to be a candidate gene for Cornelia de Lange syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009].

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