GSTM2(GSTM2) (NM_000848) Human Tagged ORF Clone

CAT#: RG210718

GSTM2 (GFP-tagged) - Human glutathione S-transferase mu 2 (muscle) (GSTM2), transcript variant 1

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  • TrueORF®

USD 443


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Size
    • 10 ug

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Specifications

Product Data
Product Name GSTM2(GSTM2) (NM_000848) Human Tagged ORF Clone
Symbol GSTM2
Synonyms GST4; GSTM; GSTM2-2; GTHMUS
Vector pCMV6-AC-GFP
Sequence Data
ORF Nucleotide Sequence
>RG210718 representing NM_000848
Red=Cloning site Blue=ORF Green=Tags(s)

TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
GCCGCGATCGCC

ATGCCCATGACACTGGGGTACTGGAACATCCGCGGGCTGGCCCATTCCATCCGCCTGCTCCTGGAATACA
CAGACTCAAGCTACGAGGAAAAGAAGTACACGATGGGGGACGCTCCTGATTATGACAGAAGCCAGTGGCT
GAATGAAAAATTCAAGCTGGGCCTGGACTTTCCCAATCTGCCCTACTTGATTGATGGGACTCACAAGATC
ACCCAGAGCAACGCCATCCTGCGGTACATTGCCCGCAAGCACAACCTGTGCGGGGAATCAGAAAAGGAGC
AGATTCGCGAAGACATTTTGGAGAACCAGTTTATGGACAGCCGTATGCAGCTGGCCAAACTCTGCTATGA
CCCAGATTTTGAGAAACTGAAACCAGAATACCTGCAGGCACTCCCTGAAATGCTGAAGCTCTACTCACAG
TTTCTGGGGAAGCAGCCATGGTCTCTTGGGGACAAGATCACCTTTGTGGATTTCATCGCTTATGATGTCC
TTGAGAGAAACCAAGTATTTGAGCCCAGCTGCCTGGATGCCTTCCCAAACCTGAAGGACTTCATCTCCCG
ATTTGAGGGCTTGGAGAAGATCTCTGCCTACATGAAGTCCAGCCGCTTCCTCCCAAGACCTGTGTTCACA
AAGATGGCTGTCTGGGGCAACAAG


ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
Protein Sequence
>RG210718 representing NM_000848
Red=Cloning site Green=Tags(s)

MPMTLGYWNIRGLAHSIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGTHKI
TQSNAILRYIARKHNLCGESEKEQIREDILENQFMDSRMQLAKLCYDPDFEKLKPEYLQALPEMLKLYSQ
FLGKQPWSLGDKITFVDFIAYDVLERNQVFEPSCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFT
KMAVWGNK

TRTRRLE - GFP Tag - V
Restriction Sites SgfI-MluI      Cloning Scheme for this gene      Plasmid Map     
Tag TurboGFP
ACCN NM_000848
ORF Size 654 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Product Components The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Reference Data
RefSeq NM_000848.2, NP_000839
RefSeq Size 1166
RefSeq ORF 657
Locus ID 2946
Cytogenetics 1p13.3
Domains GST_N, GST_C
Protein Pathways Glutathione metabolism, Metabolism of xenobiotics by cytochrome P450, Drug metabolism - cytochrome P450
Gene Summary Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. [provided by RefSeq, Jul 2008].
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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