DKK2 (NM_014421) Human Tagged ORF Clone

CAT#: RC224432L3

  • LentiORF®

Lenti ORF clone of Human dickkopf homolog 2 (Xenopus laevis) (DKK2) , Myc-DDK-tagged

  View "NM_014421" in other vectors (10)

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USD 620.00


Availability*
3 Weeks

Size
    • 10 ug


Product images

Specifications

Product Data
Product Name DKK2 (NM_014421) Human Tagged ORF Clone
Symbol DKK2
Synonyms DKK-2; DKK-2
Vector pLenti-C-Myc-DDK-P2A-Puro
Sequence Data
The ORF insert of this clone is exactly the same as(RC224432).
Restriction Sites SgfI-MluI      Cloning Scheme for this gene     
Tag Myc-DDK
ACCN NM_014421
ORF Size 777 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Product Components The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Reference Data
RefSeq NM_014421.2, NP_055236
RefSeq Size 3659
RefSeq ORF 780
Locus ID 27123
Cytogenetics 4q25
Protein Families Stem cell relevant signaling - Wnt Signaling pathway, Secreted Protein, ES Cell Differentiation/IPS, Adult stem cells, Cancer stem cells, Druggable Genome
Protein Pathways Wnt signaling pathway
MW 28.45 kDa
Gene Summary This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. It can act as either an agonist or antagonist of Wnt/beta-catenin signaling, depending on the cellular context and the presence of the co-factor kremen 2. Activity of this protein is also modulated by binding to the Wnt co-receptor LDL-receptor related protein 6 (LRP6). [provided by RefSeq, Jul 2008].

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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