PRMT1 (NM_001536) Human Tagged ORF Clone

CAT#: RC224239L1

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  • LentiORF®

Lenti ORF clone of Human protein arginine methyltransferase 1 (PRMT1), transcript variant 1 , Myc-DDK-tagged

  View "NM_001536" in other vectors (11)

USD 690.00


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Size
    • 10 ug


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Specifications

Product Data
Product Name PRMT1 (NM_001536) Human Tagged ORF Clone
Symbol PRMT1
Synonyms ANM1; HCP1; HRMT1L2; IR1B4
Vector pLenti-C-Myc-DDK
E. coli Selection Chloramphenicol (34 ug/mL)
Sequence Data
The ORF insert of this clone is exactly the same as(RC224239).
Restriction Sites SgfI-MluI      Cloning Scheme for this gene     
Tag Myc-DDK
ACCN NM_001536
ORF Size 1113 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Product Components The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Reference Data
RefSeq NM_001536.3, NP_001527
RefSeq Size 1386
RefSeq ORF 1116
Locus ID 3276
Cytogenetics 19q13.33
MW 42.3 kDa
Gene Summary This gene encodes a member of the protein arginine N-methyltransferase (PRMT) family. Post-translational modification of target proteins by PRMTs plays an important regulatory role in many biological processes, whereby PRMTs methylate arginine residues by transferring methyl groups from S-adenosyl-L-methionine to terminal guanidino nitrogen atoms. The encoded protein is a type I PRMT and is responsible for the majority of cellular arginine methylation activity. Increased expression of this gene may play a role in many types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Dec 2011]

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