XPF(ERCC4) (NM_005236) Human Tagged ORF Clone

CAT#: RC223300L1

Lenti ORF clone of Human excision repair cross-complementing rodent repair deficiency, complementation group 4 (ERCC4) , Myc-DDK-tagged

Specifications

Product Data

• Product Name: XPF(ERCC4) (NM_005236) Human Tagged ORF Clone
• Symbol: ERCC4
• Synonyms: ERCC11; FANCQ; RAD1; XFEPS; XPF
• Vector: pLenti-C-Myc-DDK
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC223300).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• Tag: Myc-DDK
• ACCN: NM_005236
• ORF Size: 2748 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.

Reference Data

• RefSeq: NM_005236.1, NP_005227
• RefSeq Size: 2751
• RefSeq ORF: 2751
• Locus ID: 2072
• Cytogenetics: 16p13.12
• Protein Families: Druggable Genome
• Protein Pathways: Nucleotide excision repair
• MW: 104.3 kDa
• Gene Summary: The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause of xeroderma pigmentosum complementation group F (XP-F), or xeroderma pigmentosum VI (XP6).[provided by RefSeq, Mar 2009].