PDCD10 (NM_145859) Human Tagged ORF Clone

CAT#: RC221815L1

Lenti ORF clone of Human programmed cell death 10 (PDCD10), transcript variant 2 , Myc-DDK-tagged

Clone Modification / Custom Cloning Service

  • LentiORF®

USD 598.00


Availability*
In Stock

Size
    • 10 ug

Product images

Specifications

Product Data
Product Name PDCD10 (NM_145859) Human Tagged ORF Clone
Symbol PDCD10
Synonyms CCM3; TFAR15
Vector pLenti-C-Myc-DDK
Sequence Data
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC221815).
Restriction Sites SgfI-MluI      Cloning Scheme for this gene     
Tag Myc-DDK
ACCN NM_145859
ORF Size 636 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Product Components The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Reference Data
RefSeq NM_145859.1, NP_665858
RefSeq Size 1313
RefSeq ORF 639
Locus ID 11235
Cytogenetics 3q26.1
Protein Families Druggable Genome
MW 24.5 kDa
Gene Summary This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008].
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (4)