TSH Receptor (TSHR) (NM_000369) Human Tagged ORF Clone

CAT#: RC220499L1

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  • LentiORF®

Lenti ORF clone of Human thyroid stimulating hormone receptor (TSHR), transcript variant 1, Myc-DDK-tagged

  View "NM_000369" in other vectors (10)

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USD 1,380.00


Availability*
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Size
    • 10 ug


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Specifications

Product Data
Product Name TSH Receptor (TSHR) (NM_000369) Human Tagged ORF Clone
Type Human Tagged ORF Clone
Tag Myc-DDK
Symbol TSHR
Synonyms CHNG1; hTSHR-I; LGR3
Vector pLenti-C-Myc-DDK
E. coli Selection Chloramphenicol (34 ug/mL)
Cell Selection None
Sequence Data
The ORF insert of this clone is exactly the same as(RC220499).
Restriction Sites SgfI-MluI      Cloning Scheme for this gene     
Tag Myc-DDK
ACCN NM_000369
ORF Size 2292 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Product Components The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Reference Data
RefSeq NM_000369.2, NP_000360.2
RefSeq Size 4410
RefSeq ORF 2295
Locus ID 7253
Cytogenetics 14q31.1
Protein Families Druggable Genome, GPCR, Transmembrane
Protein Pathways Autoimmune thyroid disease, Neuroactive ligand-receptor interaction
MW 86.83 kDa
Gene Summary The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]

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