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KAT6B (NM_012330) Human Tagged ORF Clone
CAT#: RC219702
- TrueORF®
KAT6B (Myc-DDK-tagged)-Human MYST histone acetyltransferase (monocytic leukemia) 4 (MYST4)
ORF Plasmid: tGFP
"NM_012330" in other vectors (2)
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Frequently bought together (5)
DDK Rabbit monoclonal antibody, recognizing both N- and C-terminal tags
USD 198.00
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Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | Myc-DDK |
| Symbol | KAT6B |
| Synonyms | GTPTS; MORF; MOZ2; MYST4; qkf; querkopf; ZC2HC6B |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RC219702 representing NM_012330
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGTAAAACTTGCAAACCCACTTTATACAGAGTGGATTCTTGAAGCTATACAGAAAATAAAAAAGCAAA AGCAAAGGCCCTCTGAAGAGAGAATCTGCCATGCGGTCAGTACTTCCCATGGGTTGGATAAGAAGACAGT CTCTGAACAGCTGGAACTCAGTGTTCAGGATGGCTCAGTTCTCAAAGTCACCAACAAAGGCCTTGCCTCC TATAAGGACCCAGACAACCCTGGGCGCTTTTCATCAGTTAAACCAGGCACTTTTCCTAAGTCAGCCAAGG GGTCTAGAGGATCATGTAATGATCTCCGCAATGTGGATTGGAATAAACTTTTAAGGAGAGCAATTGAAGG ACTTGAGGAGCCGAATGGCTCCTCCCTGAAGAACATAGAGAAGTATCTCAGAAGTCAAAGTGATCTCACA AGCACCACCAACAACCCAGCCTTTCAGCAGCGGCTGCGACTGGGGGCCAAACGCGCTGTGAATAATGGGA GGTTACTGAAAGACGGACCGCAGTACAGGGTCAATTATGGGAGCTTAGATGGCAAAGGGGCACCTCAGTA TCCCAGTGCATTCCCATCCTCGCTCCCACCTGTCAGCCTTCTACCCCATGAGAAAGACCAGCCCCGTGCT GATCCCATTCCAATATGTAGCTTCTGTTTGGGGACTAAAGAATCAAATCGTGAAAAGAAACCAGAAGAAC TCCTCTCTTGTGCAGATTGTGGCAGTAGTGGACACCCATCCTGTTTGAAATTTTGTCCTGAATTAACAAC AAATGTAAAGGCCTTAAGGTGGCAGTGCATCGAATGCAAGACATGCAGTGCCTGTAGAGTCCAAGGCAGA AATGCTGATAATATGCTTTTTTGTGATTCCTGTGATAGAGGATTTCATATGGAATGCTGTGACCCACCAC TTTCCAGAATGCCAAAAGGGATGTGGATTTGCCAAGTCTGCAGACCAAAGAAAAAGGGAAGAAAACTACT TCATGAGAAAGCTGCACAAATAAAACGACGATATGCAAAACCCATTGGACGACCGAAAAATAAATTAAAG CAACGATTGTTGTCTGTAACCAGTGATGAAGGATCCATGAATGCATTCACAGGAAGGGGGTCACCTGGTA GGGGTCAAAAGACTAAAGTCTGTACCACACCTTCATCTGGTCATGCTGCATCTGGGAAGGACTCAAGCAG CAGATTGGCTGTTACAGACCCCACTCGGCCTGGTGCCACCACCAAAATCACCACCACCTCCACCTACATT TCTGCCTCTACACTTAAAGTTAACAAGAAAACCAAAGGGCTCATTGATGGCCTTACTAAGTTTTTTACAC CATCACCTGATGGTCGCAGATCACGAGGTGAAATTATAGACTTTTCAAAGCACTATCGTCCAAGGAAAAA GGTCTCTCAGAAACAGTCATGCACTTCTCATGTGTTGGCTACAGGTACCACACAAAAGCTAAAACCTCCA CCTTCTTCACTTCCACCCCCAACCCCCATCTCCGGTCAGAGCCCCAGTTCACAAAAGTCCAGCACGGCCA CTTCTTCTCCCTCTCCCCAGAGTTCTTCCAGCCAGTGCAGTGTGCCCTCCCTGAGCAGCCTTACCACTAA CAGCCAGCTGAAGGCACTCTTTGATGGGCTTTCTCATACTATACCACTCAGGGACAGTCTCGCAAAAAGG GACACCCCGAGTTATGCACCACCCAAACGTATGCGTCGTAAAACTGAATTATCTTCCACGGCAAAATCTA AAGCCCACTTCTTTGGCAAAAGAGATATTAGAAGTCGGTTTATTTCTCACTCCTCCTCCTCTAGCTGGGG GATGGCTAGAGGAAGTATTTTTAAAGCAATTGCTCACTTCAAGCGAACAACTTTCCTTAAAAAGCACAGG ATGCTAGGCAGATTAAAATATAAAGTGACCCCTCAGATGGGGACCCCCTCACCAGGGAAGGGGAGCTTGA CAGACGGAAGGATTAAACCTGATCAGGATGATGATACTGAAATAAAAATAAACATCAAACAAGAAAGTGC AGATGTAAATGTGATTGGAAACAAGGATGTCGTTACTGAAGAGGATTTGGATGTTTTTAAGCAGGCCCAG GAACTTTCTTGGGAGAAAATAGAGTGTGAGAGTGGGGTGGAAGACTGTGGCCGGTACCCTTCTGTGATTG AATTTGGTAAATATGAAATCCAAACCTGGTACTCCTCGCCTTACCCACAGGAATATGCAAGATTACCAAA GCTTTACCTGTGTGAATTCTGTCTTAAATATATGAAAAGTAAAAATATTTTGCTAAGACACTCCAAGAAG TGTGGATGGTTTCATCCTCCAGCAAATGAAATTTACCGAAGGAAAGACCTTTCAGTATTTGAGGTTGATG GGAATATGAGCAAAATTTATTGCCAAAACCTTTGCTTGTTAGCCAAGCTCTTCCTGGACCACAAAACGTT GTATTATGATGTCGAGCCATTCCTTTTTTATGTCCTTACAAAAAATGATGAAAAGGGCTGTCATCTGGTT GGATACCTCTCTAAGGAAAAGCTTTGCCAGCAGAAGTATAATGTCTCCTGCATAATGATCATGCCCCAGC ACCAAAGGCAAGGATTTGGACGGTTTCTCATTGATTTCAGCTATTTGCTTTCTAGAAGAGAAGGCCAAGC AGGGTCTCCTGAAAAGCCTCTCTCCGATCTGGGCCGTCTCTCCTACCTGGCATATTGGAAGAGCGTCATC TTGGAGTATCTCTACCACCACCATGAGAGGCACATCAGCATCAAGGCAATTAGCAGAGCGACGGGCATGT GCCCACATGACATTGCCACCACTCTGCAGCACCTCCACATGATCGACAAGAGAGATGGCAGATTTGTCAT CATTAGACGGGAAAAGTTGATATTGAGCCACATGGAAAAGCTGAAAACCTGTTCCAGAGCCAATGAACTT GATCCAGACAGTCTGAGGTGGACCCCAATTTTAATTTCTAATGCTGCAGTGTCTGAAGAAGAGCGAGAAG CTGAGAAAGAGGCTGAGCGGCTAATGGAACAAGCTAGCTGCTGGGAGAAGGAGGAACAAGAAATCCTGTC AACTAGAGCTAACAGTAGGCAATCACCTGCAAAAGTACAATCGAAAAATAAATATTTGCATTCCCCGGAG AGCCGGCCAGTCACAGGGGAGCGAGGGCAGCTGCTGGAGCTGTCTAAAGAGAGCAGTGAAGAAGAAGAGG AGGAGGAGGACGAGGAGGAGGAAGAAGAGGAGGAAGAAGAGGAAGAGGATGAAGAGGAGGAAGAAGAGGA AGAAGAAGAAGAAGAAGAAGAAAATATTCAAAGCTCTCCCCCAAGATTGACGAAACCACAGTCAGTTGCC ATAAAGAGAAAGAGGCCTTTTGTACTAAAGAAGAAAAGGGGTCGTAAACGCAGGAGGATCAACAGCAGTG TAACAACAGAGACCATTTCAGAGACGACAGAAGTACTGAATGAGCCCTTTGACAACTCAGATGAAGAGAG GCCAATGCCACAGCTGGAGCCTACCTGTGAGATTGAAGTGGAGGAAGATGGCAGGAAGCCAGTCCTGAGA AAAGCATTCCAGCATCAGCCTGGGAAGAAAAGACAAACAGAGGAAGAGGAAGGAAAAGACAATCATTGCT TCAAGAATGCTGACCCTTGTAGAAACAATATGAATGATGATTCAAGTAACTTGAAAGAAGGCAGTAAAGA CAATCCCGAACCTCTAAAGTGCAAACAAGTGTGGCCAAAAGGAACAAAGCGCGGTCTATCTAAGTGGAGG CAAAACAAAGAGAGGAAGACCGGATTTAAACTGAATTTGTACACCCCGCCAGAAACACCCATGGAGCCTG ACGAGCAGGTAACAGTGGAAGAACAGAAGGAGACTTCAGAAGGAAAAACCAGCCCCAGTCCCATCAGGAT TGAGGAGGAGGTCAAGGAAACTGGGGAAGCCCTGTTGCCTCAAGAGGAAAACAGAAGGGAAGAAACATGT GCCCCTGTAAGTCCAAACACATCACCAGGTGAAAAACCAGAAGATGATCTCATCAAACCTGAGGAAGAGG AAGAGGAGGAGGAGGAGGAAGAGGAAGAAGAGGAAGAAGAGGAAGGGGAAGAAGAAGAAGGAGGAGGAAA TGTAGAAAAAGATCCAGATGGTGCTAAAAGCCAAGAAAAAGAGGAACCAGAAATCTCCACGGAAAAAGAA GACTCTGCACGTTTGGATGATCACGAAGAGGAGGAGGAAGAGGATGAAGAGCCATCCCACAACGAGGACC ATGATGCCGATGACGAGGATGACAGCCACATGGAGTCTGCCGAAGTGGAGAAGGAAGAGCTGCCCAGAGA AAGCTTCAAAGAAGTACTGGAAAACCAGGAGACTTTTTTAGACCTTAATGTGCAGCCTGGTCACTCGAAC CCAGAGGTCTTAATGGACTGTGGCGTCGACCTGACAGCTTCTTGTAACAGTGAGCCCAAGGAGCTTGCTG GGGACCCTGAAGCTGTACCCGAATCTGACGAGGAGCCACCCCCAGGAGAACAGGCACAGAAGCAGGACCA AAAGAACAGCAAGGAAGTCGATACAGAGTTCAAAGAGGGAAACCCAGCAACCATGGAAATCGACTCTGAG ACTGTCCAGGCCGTTCAGTCTTTGACCCAGGAGAGCAGCGAACAGGACGACACCTTTCAGGATTGTGCCG AGACTCAAGAGGCCTGTAGAAGCCTACAGAACTACACCCGTGCAGACCAAAGTCCACAGATTGCCACCAC GCTCGACGATTGCCAACAGTCGGACCACAGTAGCCCAGTTTCATCCGTCCACTCCCATCCTGGCCAGTCC GTACGTTCTGTCAACAGCCCAAGTGTCCCTGCTCTGGAAAACAGCTACGCCCAAATCAGCCCAGATCAAA GTGCCATCTCAGTGCCATCTCTGCAGAACATGGAAACCAGTCCCATGATGGATGTCCCATCAGTTTCAGA TCATTCACAGCAAGTCGTAGACAGTGGATTTAGTGACCTGGGCAGTATCGAGAGCACAACTGAGAACTAC GAAAACCCAAGCAGCTACGATTCTACTATGGGAGGCAGCATCTGTGGAAACGGCTCTTCACAGAACAGCT GCTCCTATAGCAACCTCACCTCCAGCAGTCTGACACAGAGCAGCTGTGCTGTCACCCAGCAGATGTCCAA CATCAGCGGGAGCTGCAGCATGCTGCAGCAAACCAGCATCAGCTCCCCTCCGACCTGCAGCGTCAAGTCT CCTCAAGGCTGTGTGGTGGAGAGGCCTCCGAGCAGCAGCCAGCAGCTGGCTCAGTGCAGCATGGCTGCTA ACTTCACCCCACCCATGCAGCTGGCTGAAATCCCCGAGACGAGCAACGCCAACATTGGCTTATACGAGCG AATGGGTCAGAGTGATTTTGGGGCTGGGCATTACCCGCAGCCGTCAGCCACCTTCAGCCTTGCCAAACTG CAGCAGTTAACTAATACACTTATTGATCATTCATTGCCTTACAGCCATTCCGCTGCTGTGACTTCCTATG CAAACAGTGCCTCTTTGTCCACACCATTAAGTAACACAGGGCTTGTTCAACTTTCTCAGTCTCCACACTC CGTCCCTGGGGGACCCCAAGCACAAGCTACCATGACCCCACCCCCCAACCTGACTCCTCCTCCAATGAAT CTGCCGCCGCCTCTTTTGCAACGGAACATGGCTGCATCAAATATTGGCATCTCTCACAGCCAAAGACTGC AAACCCAGATTGCCAGCAAGGGCCACATCTCCATGAGAACCAAGTCAGCGTCTCTGTCACCAGCCGCTGC CACCCATCAGTCACAAATCTATGGGCGCTCCCAGACTGTAGCCATGCAGGGTCCTGCACGGACTTTAACG ATGCAAAGAGGCATGAACATGAGTGTGAACCTGATGCCAGCGCCAGCCTACAATGTCAACTCTGTGAACA TGAACATGAACACTCTCAACGCCATGAATGGGTACAGCATGTCCCAGCCAATGATGAACAGTGGCTACCA CAGCAATCATGGCTATATGAATCAAACGCCCCAATACCCTATGCAGATGCAGATGGGCATGATGGGCACC CAGCCATATGCCCAGCAGCCAATGCAGACCCCACCCCACGGTAACATGATGTACACGGCCCCCGGACATC ACGGCTACATGAACACAGGCATGTCCAAACAGTCTCTCAATGGCTCCTACATGAGAAGG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC219702 representing NM_012330
Red=Cloning site Green=Tags(s) MVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSVLKVTNKGLAS YKDPDNPGRFSSVKPGTFPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEEPNGSSLKNIEKYLRSQSDLT STTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYGSLDGKGAPQYPSAFPSSLPPVSLLPHEKDQPRA DPIPICSFCLGTKESNREKKPEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGR NADNMLFCDSCDRGFHMECCDPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLK QRLLSVTSDEGSMNAFTGRGSPGRGQKTKVCTTPSSGHAASGKDSSSRLAVTDPTRPGATTKITTTSTYI SASTLKVNKKTKGLIDGLTKFFTPSPDGRRSRGEIIDFSKHYRPRKKVSQKQSCTSHVLATGTTQKLKPP PSSLPPPTPISGQSPSSQKSSTATSSPSPQSSSSQCSVPSLSSLTTNSQLKALFDGLSHTIPLRDSLAKR DTPSYAPPKRMRRKTELSSTAKSKAHFFGKRDIRSRFISHSSSSSWGMARGSIFKAIAHFKRTTFLKKHR MLGRLKYKVTPQMGTPSPGKGSLTDGRIKPDQDDDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQ ELSWEKIECESGVEDCGRYPSVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKK CGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTKNDEKGCHLV GYLSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSPEKPLSDLGRLSYLAYWKSVI LEYLYHHHERHISIKAISRATGMCPHDIATTLQHLHMIDKRDGRFVIIRREKLILSHMEKLKTCSRANEL DPDSLRWTPILISNAAVSEEEREAEKEAERLMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPE SRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVA IKRKRPFVLKKKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLR KAFQHQPGKKRQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPKGTKRGLSKWR QNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLPQEENRREETC APVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKE DSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVEKEELPRESFKEVLENQETFLDLNVQPGHSN PEVLMDCGVDLTASCNSEPKELAGDPEAVPESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSE TVQAVQSLTQESSEQDDTFQDCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSPVSSVHSHPGQS VRSVNSPSVPALENSYAQISPDQSAISVPSLQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTENY ENPSSYDSTMGGSICGNGSSQNSCSYSNLTSSSLTQSSCAVTQQMSNISGSCSMLQQTSISSPPTCSVKS PQGCVVERPPSSSQQLAQCSMAANFTPPMQLAEIPETSNANIGLYERMGQSDFGAGHYPQPSATFSLAKL QQLTNTLIDHSLPYSHSAAVTSYANSASLSTPLSNTGLVQLSQSPHSVPGGPQAQATMTPPPNLTPPPMN LPPPLLQRNMAASNIGISHSQRLQTQIASKGHISMRTKSASLSPAAATHQSQIYGRSQTVAMQGPARTLT MQRGMNMSVNLMPAPAYNVNSVNMNMNTLNAMNGYSMSQPMMNSGYHSNHGYMNQTPQYPMQMQMGMMGT QPYAQQPMQTPPHGNMMYTAPGHHGYMNTGMSKQSLNGSYMRR TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Chromatograms |
CHROMATOGRAMS
 Sequencher program is needed, download here. |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_012330 |
| ORF Size | 6219 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_012330.1, NP_036462.1 |
| RefSeq Size | 6537 bp |
| RefSeq ORF | 6222 bp |
| Locus ID | 23522 |
| UniProt ID | Q8WYB5 |
| Cytogenetics | 10q22.2 |
| Domains | PHD, MOZ_SAS, linker_histone |
| Protein Families | Druggable Genome |
| MW | 231.2 kDa |
| Gene Summary | The protein encoded by this gene is a histone acetyltransferase and component of the MOZ/MORF protein complex. In addition to its acetyltransferase activity, the encoded protein has transcriptional activation activity in its N-terminal end and transcriptional repression activity in its C-terminal end. This protein is necessary for RUNX2-dependent transcriptional activation and could be involved in brain development. Mutations have been found in patients with genitopatellar syndrome. A translocation of this gene and the CREBBP gene results in acute myeloid leukemias. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012] |
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