HFE (NM_139006) Human Tagged ORF Clone

CAT#: RC219316L1

Lenti ORF clone of Human hemochromatosis (HFE), transcript variant 6 , Myc-DDK-tagged

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  • LentiORF®

USD 618


Availability*
3 Weeks

Size
    • 10 ug

Product images

Specifications

Product Data
Product Name HFE (NM_139006) Human Tagged ORF Clone
Symbol HFE
Synonyms HFE1; HH; HLA-H; MVCD7; TFQTL2
Vector pLenti-C-Myc-DDK
Sequence Data
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC219316).
Restriction Sites SgfI-MluI      Cloning Scheme for this gene     
Tag Myc-DDK
ACCN NM_139006
ORF Size 1002 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Product Components The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Reference Data
RefSeq NM_139006.1, NP_620575
RefSeq Size 1045
RefSeq ORF 1005
Locus ID 3077
Cytogenetics 6p22.2
Domains MHC_I, ig, IGc1
Protein Families Transmembrane, Druggable Genome
MW 36.2 kDa
Gene Summary The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined. [provided by RefSeq, Jul 2008].
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.