CLDN19 (NM_148960) Human Tagged ORF Clone

CAT#: RC216887L3

  • LentiORF®

Lenti ORF clone of Human claudin 19 (CLDN19), transcript variant 1 , Myc-DDK-tagged

  View "NM_148960" in other vectors (10)

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USD 620.00


Availability*
3 Weeks

Size
    • 10 ug


Product images

Specifications

Product Data
Product Name CLDN19 (NM_148960) Human Tagged ORF Clone
Symbol CLDN19
Synonyms HOMG5; HOMG5
Vector pLenti-C-Myc-DDK-P2A-Puro
Sequence Data
The ORF insert of this clone is exactly the same as(RC216887).
Restriction Sites SgfI-MluI      Cloning Scheme for this gene     
Tag Myc-DDK
ACCN NM_148960
ORF Size 672 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Product Components The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Reference Data
RefSeq NM_148960.1, NP_683763
RefSeq Size 2859
RefSeq ORF 675
Locus ID 149461
Cytogenetics 1p34.2
Protein Families Transmembrane
Protein Pathways Cell adhesion molecules (CAMs), Tight junction, Leukocyte transendothelial migration
MW 23 kDa
Gene Summary The product of this gene belongs to the claudin family. It plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Defects in this gene are the cause of hypomagnesemia renal with ocular involvement (HOMGO). HOMGO is a progressive renal disease characterized by primary renal magnesium wasting with hypomagnesemia, hypercalciuria and nephrocalcinosis associated with severe ocular abnormalities such as bilateral chorioretinal scars, macular colobomata, significant myopia and nystagmus. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jun 2010].

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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