DNASE2B (NM_021233) Human Tagged ORF Clone

CAT#: RC212192

DNASE2B (Myc-DDK-tagged)-Human deoxyribonuclease II beta (DNASE2B), transcript variant 1

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Size
    • 10 ug

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Specifications

Product Data
Product Name DNASE2B (NM_021233) Human Tagged ORF Clone
Symbol DNASE2B
Synonyms DLAD
Vector pCMV6-Entry
Sequence Data
ORF Nucleotide Sequence
>RC212192 representing NM_021233
Red=Cloning site Blue=ORF Green=Tags(s)

TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
GCCGCGATCGCC

ATGATGGCAAGACTGCTAAGAACATCCTTTGCTTTGCTCTTCCTTGGCCTCTTTGGGGTGCTGGGGGCAG
CAACAATTTCATGCAGAAATGAAGAAGGGAAAGCTGTGGACTGGTTTACTTTTTATAAGTTACCTAAAAA
ACAAAACAAGGAAAGTGGAGAGACTGGGTTAGAGTACCTGTACCTAGACTCTACAACTAGAAGCTGGAGG
AAGAGTGAGCAACTAATGAATGACACCAAGAGTGTTTTGGGAAGGACATTACAACAGCTATATGAAGCAT
ATGCCTCTAAGAGTAACAACACAGCCTATCTAATATACAATGATGGAGTCCCTAAACCTGTGAATTACAG
CAGAAAGTATGGACACACCAAAGGTTTACTGCTGTGGAACAGAGTTCAAGGGTTCTGGCTGATTCATTCC
ATCCCTCAGTTTCCTCCAATTCCGGAAGAAGGCTATGATTATCCACCCACAGGGAGACGAAATGGACAAA
GTGGCATCTGCATAACTTTCAAGTACAACCAGTATGAGGCAATAGATTCTCAGCTCTTGGTCTGCAACCC
CAACGTCTATAGCTGCTCCATCCCAGCCACCTTTCACCAGGAGCTCATTCACATGCCCCAGCTGTGCACC
AGGGCCAGCTCATCAGAGATTCCTGGCAGGCTCCTCACCACACTTCAGTCGGCCCAGGGACAAAAATTCC
TCCATTTTGCAAAGTCGGATTCTTTTCTTGACGACATCTTTGCAGCCTGGATGGCTCAACGGCTGAAGAC
ACACTTGTTAACAGAAACCTGGCAGCGAAAAAGACAAGAGCTTCCTTCAAACTGCTCCCTTCCTTACCAT
GTCTACAATATAAAAGCAATTAAATTATCACGACACTCTTATTTCAGTTCTTATCAAGATCACGCCAAGT
GGTGTATTTCCCAAAAGGGCACCAAAAATCGCTGGACATGTATTGGAGACCTAAATCGGAGTCCACACCA
AGCCTTCAGAAGTGGAGGATTCATTTGTACCCAGAATTGGCAAATTTACCAAGCATTTCAAGGATTAGTA
TTATACTATGAAAGCTGTAAG


ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
ACAAGGATGACGACGATAAG
GTTTAA
Protein Sequence
>RC212192 representing NM_021233
Red=Cloning site Green=Tags(s)

MMARLLRTSFALLFLGLFGVLGAATISCRNEEGKAVDWFTFYKLPKKQNKESGETGLEYLYLDSTTRSWR
KSEQLMNDTKSVLGRTLQQLYEAYASKSNNTAYLIYNDGVPKPVNYSRKYGHTKGLLLWNRVQGFWLIHS
IPQFPPIPEEGYDYPPTGRRNGQSGICITFKYNQYEAIDSQLLVCNPNVYSCSIPATFHQELIHMPQLCT
RASSSEIPGRLLTTLQSAQGQKFLHFAKSDSFLDDIFAAWMAQRLKTHLLTETWQRKRQELPSNCSLPYH
VYNIKAIKLSRHSYFSSYQDHAKWCISQKGTKNRWTCIGDLNRSPHQAFRSGGFICTQNWQIYQAFQGLV
LYYESCK

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Chromatograms CHROMATOGRAMS
Sequencher program is needed, download here.
Restriction Sites SgfI-MluI      Cloning Scheme for this gene      Plasmid Map     
Tag Myc-DDK
ACCN NM_021233
ORF Size 1071 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Product Components The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Reference Data
RefSeq NM_021233.1, NP_067056
RefSeq Size 1279
RefSeq ORF 1086
Locus ID 58511
Cytogenetics 1p31.1-p22.3
Protein Families Transmembrane
Protein Pathways Lysosome
MW 38.7 kDa
Gene Summary The protein encoded by this gene shares considerable sequence similarity to, and is structurally related to DNase II. The latter is a well characterized endonuclease that catalyzes DNA hydrolysis in the absence of divalent cations at acidic pH. Unlike DNase II which is ubiquitously expressed, expression of this gene product is restricted to the salivary gland and lungs. The gene has been localized to chromosome 1p22.3 adjacent (and in opposite orientation) to the uricase pseudogene. Two transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations