COMP (NM_000095) Human Tagged ORF Clone

CAT#: RC211080L2

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  • LentiORF®

Lenti ORF clone of Human cartilage oligomeric matrix protein (COMP), mGFP tagged

  View "NM_000095" in other vectors (11)

USD 860.00


Availability*
3 Weeks

Size
    • 10 ug


Product images

Specifications

Product Data
Product Name COMP (NM_000095) Human Tagged ORF Clone
Symbol COMP
Synonyms EDM1; EPD1; MED; PSACH; THBS5; TSP5
Vector pLenti-C-mGFP
E. coli Selection Chloramphenicol (34 ug/mL)
Sequence Data
The ORF insert of this clone is exactly the same as(RC211080).
Restriction Sites SgfI-RsrII      Cloning Scheme for this gene     
Tag mGFP
ACCN NM_000095
ORF Size 2271 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Product Components The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Reference Data
RefSeq NM_000095.2, NP_000086
RefSeq Size 2471
RefSeq ORF 2274
Locus ID 1311
Cytogenetics 19p13.11
Domains EGF_CA, tsp_3, EGF, EGF
Protein Families Druggable Genome, Secreted Protein
Protein Pathways ECM-receptor interaction, Focal adhesion, TGF-beta signaling pathway
MW 82.9 kDa
Gene Summary The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Contraction or expansion of a 5 aa aspartate repeat and other mutations can cause pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED). [provided by RefSeq, Jul 2016]

Other Versions

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Rabbit Polyclonal Anti-COMP Antibody
    • 100 ul

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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